Roman Lesyk

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	All	Since 2016
Citations	4932	2892
h-index	38	28
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Co-authors

Borys ZimenkovskyDanylo Halytsky Lviv National Medical UniversityVerified email at meduniv.lviv.ua
Dmytro HavrylyukResearch Assistant Professor, Department of Chemistry, University of KentuckyVerified email at uky.edu
Andrzej GzellaProfesor UM, Poznan University of Medical SciencesVerified email at ump.edu.pl
Danylo KaminskyyDanylo Halytsky Lviv National Medical University, Dep of Pharm., Org. Bioorg. ChemVerified email at meduniv.lviv.ua
Anna Kryshchyshyn-DylevychDanylo Halytsky Lviv National Medical UniversityVerified email at meduniv.lviv.ua
Dmytro AtamanyukSenior Scientist, AB-ScienceVerified email at ab-science.com
Rostyslav StoikaHead of Department, Institute of Cell Biology, NAS of Ukraine; Professor of Department of NormalVerified email at cellbiol.lviv.ua
Grellier PhilippeProfesseur, Muséum National d'Histoire Naturelle, Paris, FranceVerified email at mnhn.fr
Andrii LozynskyiDanylo Halytsky Lviv National Medical University, Department of Pharmaceutical, Organic andVerified email at meduniv.lviv.ua
Holota SerhiiPhD, Lviv National Medical University, Volyn National UniversityVerified email at vnu.edu.ua
Lucjusz ZaprutkoUniwersytet Medyczny wPoznaniuVerified email at ump.edu.pl
Ivanna Subtelna (Іванна Субтельна, I...Львівський державний медичний університет імені Данила ГалицькогоVerified email at meduniv.lviv.ua
Kobylinska Lesya Кобилінська Л.І.Danylo Halytsky Lviv National Medical University, Department of BiochemistryVerified email at meduniv.lviv.ua
Nataliya ZeliskoDanylo Halytsky Lviv National Medical UniversityVerified email at meduniv.lviv.ua
Людмила Маркіянівна Мосула, Liudm...к.фарм.н., доцент кафедри фармацевтичної хімії Тернопільського національного медичного університетуVerified email at tdmu.edu.ua
Oleg DevinyakUzhhorod National University (Ужгородський національний університет)Verified email at uzhnu.edu.ua
Rostyslav PanchukSenior Scientist, Institute of Cell Biology NAS of UkraineVerified email at cellbiol.lviv.ua
Roman KutsykПрофесор мікробіологіVerified email at ifnmu.edu.ua
Magdalena WojtyraDanylo Halytsky Lviv National Medical UniversityVerified email at meduniv.lviv.ua
Volodymyr HorishnyDanylo Halytsky Lviv National Medical UniversityVerified email at meduniv.lviv.ua

Roman Lesyk

Danylo Halytsky Lviv National Medical University

Verified email at org.lviv.net

medicinal chemistry heterocyclic chemistry synthesis


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4-Thiazolidones: centenarian history, current status and perspectives for modern organic and medicinal chemistry RB Lesyk, BS Zimenkovsky Current Organic Chemistry 8 (16), 1547-1577, 2004	328	2004
Synthesis of novel thiazolone-based compounds containing pyrazoline moiety and evaluation of their anticancer activity D Havrylyuk, B Zimenkovsky, O Vasylenko, L Zaprutko, A Gzella, R Lesyk European journal of medicinal chemistry 44 (4), 1396-1404, 2009	319	2009
Synthesis and anticancer activity evaluation of 4-thiazolidinones containing benzothiazole moiety D Havrylyuk, L Mosula, B Zimenkovsky, O Vasylenko, A Gzella, R Lesyk European journal of medicinal chemistry 45 (11), 5012-5021, 2010	267	2010
Synthesis of new 4-thiazolidinone-, pyrazoline-, and isatin-based conjugates with promising antitumor activity D Havrylyuk, B Zimenkovsky, O Vasylenko, A Gzella, R Lesyk Journal of Medicinal Chemistry 55 (20), 8630-8641, 2012	210	2012
New 5-substituted thiazolo [3, 2-b][1, 2, 4] triazol-6-ones: synthesis and anticancer evaluation R Lesyk, O Vladzimirska, S Holota, L Zaprutko, A Gzella European journal of medicinal chemistry 42 (5), 641-648, 2007	178	2007
Anticancer thiopyrano [2,3-d][1,3] thiazol-2-ones with norbornane moiety. Synthesis, cytotoxicity, physico-chemical properties, and computational studies R Lesyk, B Zimenkovsky, D Atamanyuk, F Jensen, K Kieć-Kononowicz, ... Bioorganic & medicinal chemistry 14 (15), 5230-5240, 2006	121	2006
Thiazolidinone motif in anticancer drug discovery. Experience of DH LNMU medicinal chemistry scientific group RB Lesyk, BS Zimenkovsky, DV Kaminskyy, AP Kryshchyshyn, ... Вiopolymers and Cell, 2011	113	2011
Synthesis and anticancer activity of isatin‐based pyrazolines and thiazolidines conjugates D Havrylyuk, N Kovach, B Zimenkovsky, O Vasylenko, R Lesyk Archiv der Pharmazie 344 (8), 514-522, 2011	112	2011
Synthesis and in vitro anticancer activity of 2, 4-azolidinedione-acetic acids derivatives D Kaminskyy, B Zimenkovsky, R Lesyk European journal of medicinal chemistry 44 (9), 3627-3636, 2009	107	2009
Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones D Havrylyuk, B Zimenkovsky, O Vasylenko, CW Day, DF Smee, P Grellier, ... European journal of medicinal chemistry 66, 228-237, 2013	100	2013
Synthesis of 5-arylidene-2-amino-4-azolones and evaluation of their anticancer activity I Subtel’na, D Atamanyuk, E Szymańska, K Kieć-Kononowicz, ... Bioorganic & medicinal chemistry 18 (14), 5090-5102, 2010	98	2010
A facile synthesis and anticancer activity evaluation of spiro [thiazolidinone-isatin] conjugates D Kaminskyy, D Khyluk, O Vasylenko, L Zaprutko, R Lesyk Scientia pharmaceutica 79 (4), 763-778, 2011	97	2011
Synthetic approaches, structure activity relationship and biological applications for pharmacologically attractive pyrazole/pyrazoline–thiazolidine-based hybrids D Havrylyuk, O Roman, R Lesyk European journal of medicinal chemistry 113, 145-166, 2016	89	2016
5-Ene-4-thiazolidinones–An efficient tool in medicinal chemistry D Kaminskyy, A Kryshchyshyn, R Lesyk European journal of medicinal chemistry 140, 542-594, 2017	85	2017
Manganic encephalopathy due to “ephedrone” abuse Y Sanotsky, R Lesyk, L Fedoryshyn, I Komnatska, Y Matviyenko, S Fahn Movement disorders: official journal of the Movement Disorder Society 22 (9 …, 2007	85	2007
3D-MoRSE descriptors explained O Devinyak, D Havrylyuk, R Lesyk Journal of Molecular Graphics and Modelling 54, 194-203, 2014	82	2014
Recent developments with rhodanine as a scaffold for drug discovery D Kaminskyy, A Kryshchyshyn, R Lesyk Expert opinion on drug discovery 12 (12), 1233-1252, 2017	77	2017
Synthesis and antitrypanosomal activity of new 6, 6, 7-trisubstituted thiopyrano [2, 3-d][1, 3] thiazoles N Zelisko, D Atamanyuk, O Vasylenko, P Grellier, R Lesyk Bioorganic & medicinal chemistry letters 22 (23), 7071-7074, 2012	76	2012
Фармацевтична хімія (стероїдні гормони, їх синтетичні замінники і гетероциклічні сполуки як лікарські засоби): Підручник/За ред. БС Зіменковського ММ Туркевич, ОВ Владзімірська, РБ Лесик Вінниця: Нова Книга 464, 11, 2003	76*	2003
A new domino-Knoevenagel–hetero-Diels–Alder reaction VS Matiychuk, RB Lesyk, MD Obushak, A Gzella, DV Atamanyuk, ... Tetrahedron Letters 49 (31), 4648-4651, 2008	75*	2008

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