The molecular basis of drug resistance against hepatitis C virus NS3/4A protease inhibitors KP Romano, A Ali, C Aydin, D Soumana, A Özen, LM Deveau, C Silver, ... PLoS Pathog 8 (7), e1002832, 2012 | 246 | 2012 |
The photolyase/cryptochrome family of proteins as DNA repair enzymes and transcriptional repressors IH Kavakli, I Baris, M Tardu, Ş Gül, H Öner, S Çal, S Bulut, D Yarparvar, ... Photochemistry and photobiology 93 (1), 93-103, 2017 | 88 | 2017 |
Evaluating the role of macrocycles in the susceptibility of hepatitis C virus NS3/4A protease inhibitors to drug resistance A Ali, C Aydin, R Gildemeister, KP Romano, H Cao, A Özen, D Soumana, ... ACS chemical biology 8 (7), 1469-1478, 2013 | 71 | 2013 |
Gene editing and RNAi approaches for COVID-19 diagnostics and therapeutics B Berber, C Aydin, F Kocabas, G Guney-Esken, K Yilancioglu, ... Gene therapy 28 (6), 290-305, 2021 | 48 | 2021 |
Structural and thermodynamic effects of macrocyclization in HCV NS3/4A inhibitor MK-5172 DI Soumana, N Kurt Yilmaz, KL Prachanronarong, C Aydin, A Ali, ... ACS chemical biology 11 (4), 900-909, 2016 | 45 | 2016 |
Human CRY1 variants associate with attention deficit/hyperactivity disorder OE Onat, ME Kars, Ş Gül, K Bilguvar, Y Wu, A Özhan, C Aydın, AN Başak, ... The Journal of Clinical Investigation 130 (7), 2020 | 39 | 2020 |
The interdomain interface in bifunctional enzyme protein 3/4A (NS3/4A) regulates protease and helicase activities C Aydin, S Mukherjee, AM Hanson, DN Frick, CA Schiffer Protein Science 22 (12), 1786-1798, 2013 | 25 | 2013 |
Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling S Muratcioglu, C Aydin, E Odabasi, ES Ozdemir, EN Firat-Karalar, H Jang, ... Journal of Molecular Biology 432 (4), 1199-1215, 2020 | 20 | 2020 |
The Arg-293 of Cryptochrome1 is responsible for the allosteric regulation of CLOCK-CRY1 binding in circadian rhythm S Gul, C Aydin, O Ozcan, B Gurkan, S Surme, I Baris, IH Kavakli Journal of Biological Chemistry 295 (50), 17187-17199, 2020 | 14 | 2020 |
Simultaneously targeting the NS3 protease and helicase activities for more effective hepatitis C virus therapy J Ndjomou, MJ Corby, NL Sweeney, AM Hanson, C Aydin, A Ali, ... ACS chemical biology 10 (8), 1887-1896, 2015 | 11 | 2015 |
Resistance from Afar: Distal Mutation V36M Allosterically Modulates the Active Site to Accentuate Drug Resistance in HCV NS3/4A Protease A Özen, KH Lin, KP Romano, D Tavella, A Newton, CJ Petropoulos, ... bioRxiv, 452284, 2018 | 4 | 2018 |
Expression analyses of soluble starch synthase and starch branching enzyme isoforms in stem and leaf tissues under different photoperiods in lentil (Lens culinaris Medik.) YC Gercek, K Boztas, C Aydin, H Morgil, I Baris, GC Oz, I Tulum Biologia 77 (2), 593-607, 2022 | 1 | 2022 |
TW68, cryptochromes stabilizer, regulates fasting blood glucose levels in diabetic ob/ob and high fat-diet-induced obese mice S Surme, C Ergun, S Gul, YK Akyel, ZM Gul, O Ozcan, OS Ipek, BA Akarlar, ... Biochemical Pharmacology 218, 115896, 2023 | | 2023 |
Hepatitis C Virus Non-Structural Protein 3/4A: A Tale of Two Domains: A Dissertation C Aydin | | 2012 |