Mycobacterium tuberculosis lipomannan blocks TNF biosynthesis by regulating macrophage MAPK-activated protein kinase 2 (MK2) and microRNA miR-125b MVS Rajaram, B Ni, JD Morris, MN Brooks, TK Carlson, B Bakthavachalu, ... Proceedings of the National Academy of Sciences 108 (42), 17408-17413, 2011 | 337 | 2011 |
Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice N Wein, A Vulin, MS Falzarano, CAK Szigyarto, B Maiti, A Findlay, ... Nature medicine 20 (9), 992-1000, 2014 | 131 | 2014 |
RNP-granule assembly via Ataxin-2 disordered domains is required for long-term memory and neurodegeneration B Bakthavachalu, J Huelsmeier, IP Sudhakaran, J Hillebrand, A Singh, ... Neuron 98 (4), 754-766. e4, 2018 | 120 | 2018 |
Identification of cytoplasmic capping targets reveals a role for cap homeostasis in translation and mRNA stability C Mukherjee, DP Patil, BA Kennedy, B Bakthavachalu, R Bundschuh, ... Cell reports 2 (3), 674-684, 2012 | 107 | 2012 |
The cytoplasmic capping complex assembles on adapter protein nck1 bound to the proline-rich C-terminus of Mammalian capping enzyme C Mukherjee, B Bakthavachalu, DR Schoenberg PLoS biology 12 (8), e1001933, 2014 | 53 | 2014 |
Glucose-stimulated translation regulation of insulin by the 5′ UTR-binding proteins SD Kulkarni, B Muralidharan, AC Panda, B Bakthavachalu, A Vindu, ... Journal of Biological Chemistry 286 (16), 14146-14156, 2011 | 47 | 2011 |
The long 3′ UTR mRNA of CaMKII is essential for translation-dependent plasticity of spontaneous release in Drosophila melanogaster EA Kuklin, S Alkins, B Bakthavachalu, MC Genco, I Sudhakaran, ... Journal of Neuroscience 37 (44), 10554-10566, 2017 | 31 | 2017 |
Antagonistic roles for Ataxin-2 structured and disordered domains in RNP condensation A Singh, J Hulsmeier, AR Kandi, SS Pothapragada, J Hillebrand, ... Elife 10, e60326, 2021 | 24 | 2021 |
A minimal element in 5′ UTR of insulin mRNA mediates its translational regulation by glucose B Muralidharan, B Bakthavachalu, A Pathak, V Seshadri FEBS letters 581 (21), 4103-4108, 2007 | 24 | 2007 |
Local translation provides the asymmetric distribution of CaMKII required for associative memory formation N Chen, Y Zhang, M Adel, EA Kuklin, ML Reed, JD Mardovin, ... Current biology 32 (12), 2730-2738. e5, 2022 | 14 | 2022 |
Identification of the human PMR1 mRNA endonuclease as an alternatively processed product of the gene for peroxidasin-like protein SQ Gu, B Bakthavachalu, J Han, DP Patil, Y Otsuka, C Guda, ... RNA 18 (6), 1186-1196, 2012 | 14 | 2012 |
Dense cataract and microphthalmia (dcm) in BALB/c mice is caused by mutations in the GJA8 locus B Bakthavachalu, S Kalanke, S Galande, B Ramanamurthy, P Parab, ... Journal of genetics 89, 147-154, 2010 | 12 | 2010 |
Novel splice variant of mouse insulin2 mRNA: implications for insulin expression AC Panda, SD Kulkarni, B Muralidharan, B Bakthavachalu, V Seshadri FEBS letters 584 (6), 1169-1173, 2010 | 11 | 2010 |
A C-terminal ataxin-2 disordered region promotes Huntingtin protein aggregation and neurodegeneration in Drosophila models of Huntington’s disease J Huelsmeier, E Walker, B Bakthavachalu, M Ramaswami G3 11 (12), jkab355, 2021 | 9 | 2021 |
The transcriptional response to oxidative stress is independent of stress-granule formation A Singh, AR Kandi, D Jayaprakashappa, G Thuery, DJ Purohit, ... Molecular Biology of the Cell 33 (3), ar25, 2022 | 8 | 2022 |
Structured and disordered regions of Ataxin-2 contribute differently to the specificity and efficiency of mRNP granule formation A Petrauskas, DL Fortunati, AR Kandi, SS Pothapragada, K Agrawal, ... PLoS genetics 20 (5), e1011251, 2024 | 4 | 2024 |
Eggs of the mosquito Aedes aegypti survive desiccation by rewiring their polyamine and lipid metabolism A Prasad, S Sreedharan, B Bakthavachalu, S Laxman PLOS Biology 21 (10), e3002342, 2023 | 3 | 2023 |
Aedes aegypti eggs use rewired polyamine and lipid metabolism to survive extreme desiccation A Prasad, S Sreedharan, B Bakthavachalu, S Laxman bioRxiv, 2022.12. 30.522323, 2022 | 2 | 2022 |
Distinct developmental patterns in Anopheles stephensi organ systems K Agrawal, S Prabhakar, B Bakthavachalu, D Chaturvedi Developmental biology 508, 107-122, 2024 | | 2024 |
Ataxin-2 Disordered Region Promote Huntingtin Protein Aggregation And Neurodegeneration In Drosophila Models Of Huntington's Disease. J Huelsmeier, E Walker, B Bakthavachalu, M Ramaswami bioRxiv, 2021 | | 2021 |