| In the thick of it: HCM-causing mutations in myosin binding proteins of the thick filament SP Harris, RG Lyons, KL Bezold Circulation research 108 (6), 751-764, 2011 | 248 | 2011 |
| Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes JW McNamara, A Li, NJ Smith, S Lal, RM Graham, KB Kooiker, ... Journal of molecular and cellular cardiology 94, 65-71, 2016 | 130 | 2016 |
| Altered cardiac energetics and mitochondrial dysfunction in hypertrophic cardiomyopathy S Ranjbarvaziri, KB Kooiker, M Ellenberger, G Fajardo, M Zhao, ... Circulation 144 (21), 1714-1731, 2021 | 114 | 2021 |
| Physiological mitochondrial fragmentation is a normal cardiac adaptation to increased energy demand M Coronado, G Fajardo, K Nguyen, M Zhao, K Kooiker, G Jung, DQ Hu, ... Circulation research 122 (2), 282-295, 2018 | 104 | 2018 |
| Early-onset hypertrophic cardiomyopathy mutations significantly increase the velocity, force, and actin-activated ATPase activity of human β-cardiac myosin AS Adhikari, KB Kooiker, SS Sarkar, C Liu, D Bernstein, JA Spudich, ... Cell reports 17 (11), 2857-2864, 2016 | 88 | 2016 |
| Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment E Quarles, N Basisty, YA Chiao, G Merrihew, H Gu, MT Sweetwyne, ... Aging Cell 19 (2), e13086, 2020 | 77 | 2020 |
| Time-dependent evolution of functional vs. remodeling signaling in induced pluripotent stem cell-derived cardiomyocytes and induced maturation with biomechanical stimulation G Jung, G Fajardo, AJS Ribeiro, KB Kooiker, M Coronado, M Zhao, ... The FASEB Journal 30 (4), 1464, 2016 | 72 | 2016 |
| β-Cardiac myosin hypertrophic cardiomyopathy mutations release sequestered heads and increase enzymatic activity AS Adhikari, DV Trivedi, SS Sarkar, D Song, KB Kooiker, D Bernstein, ... Nature communications 10 (1), 2685, 2019 | 65 | 2019 |
| Contribution of the myosin binding protein C motif to functional effects in permeabilized rat trabeculae MV Razumova, KL Bezold, AY Tu, M Regnier, SP Harris The Journal of general physiology 132 (5), 575-585, 2008 | 59 | 2008 |
| Earning stripes: myosin binding protein-C interactions with actin SJ van Dijk, KL Bezold, SP Harris Pflügers Archiv-European Journal of Physiology 466, 445-450, 2014 | 58 | 2014 |
| Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super relaxed state AS Vander Roest, C Liu, MM Morck, KB Kooiker, G Jung, D Song, ... Proceedings of the National Academy of Sciences 118 (24), e2025030118, 2021 | 54 | 2021 |
| A gain-of-function mutation in the M-domain of cardiac myosin-binding protein-C increases binding to actin KL Bezold, JF Shaffer, JK Khosa, ER Hoye, SP Harris Journal of Biological Chemistry 288 (30), 21496-21505, 2013 | 46 | 2013 |
| miR-21 is associated with fibrosis and right ventricular failure S Reddy, DQ Hu, M Zhao, E Blay Jr, N Sandeep, SG Ong, G Jung, ... JCI insight 2 (9), 2017 | 40 | 2017 |
| Functional differences between the N-terminal domains of mouse and human myosin binding protein-C JF Shaffer, P Wong, KL Bezold, SP Harris Journal of Biomedicine and Biotechnology 2010, 2010 | 35 | 2010 |
| The A31P missense mutation in cardiac myosin binding protein C alters protein structure but does not cause haploinsufficiency SJ van Dijk, KB Kooiker, S Mazzalupo, Y Yang, AS Kostyukova, ... Archives of biochemistry and biophysics 601, 133-140, 2016 | 28 | 2016 |
| Modulating the tension-time integral of the cardiac twitch prevents dilated cardiomyopathy in murine hearts JD Powers, KB Kooiker, AB Mason, AE Teitgen, GV Flint, JC Tardiff, ... JCI insight 5 (20), 2020 | 21 | 2020 |
| Point mutations in the tri-helix bundle of the M-domain of cardiac myosin binding protein-C influence systolic duration and delay cardiac relaxation SJ van Dijk, KB Kooiker, NC Napierski, KD Touma, S Mazzalupo, ... Journal of molecular and cellular cardiology 119, 116-124, 2018 | 18 | 2018 |
| 4HNE impairs myocardial bioenergetics in congenital heart disease-induced right ventricular failure HTV Hwang, N Sandeep, SL Paige, S Ranjbarvaziri, DQ Hu, M Zhao, ... Circulation 142 (17), 1667-1683, 2020 | 17 | 2020 |
| Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle KB Kooiker, S Mohran, KL Turner, W Ma, G Flint, L Qi, C Gao, Y Zheng, ... bioRxiv, 2023.01. 31.526380, 2023 | 3 | 2023 |
| Correcting dilated cardiomyopathy with fibroblast-targeted p38 deficiency RC Bretherton, IM Reichardt, KA Zabrecky, AJ Goldstein, LRJ Bailey, ... bioRxiv, 2023.01. 23.523684, 2023 | 3 | 2023 |
