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Goutam Chowdhury
Goutam Chowdhury
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Cited by
Year
Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1, 4-di-N-oxide
B Ganley, G Chowdhury, J Bhansali, JS Daniels, KS Gates
Bioorganic & medicinal chemistry 9 (9), 2395-2401, 2001
1742001
Translesion synthesis across O6-alkylguanine DNA adducts by recombinant human DNA polymerases
JY Choi, G Chowdhury, H Zang, KC Angel, CC Vu, LA Peterson, ...
Journal of biological chemistry 281 (50), 38244-38256, 2006
1552006
Interstrand cross-links generated by abasic sites in duplex DNA
S Dutta, G Chowdhury, KS Gates
Journal of the American Chemical Society 129 (7), 1852-1853, 2007
1492007
DNA base damage by the antitumor agent 3-amino-1, 2, 4-benzotriazine 1, 4-dioxide (tirapazamine)
M Birincioglu, P Jaruga, G Chowdhury, H Rodriguez, M Dizdaroglu, ...
Journal of the American Chemical Society 125 (38), 11607-11615, 2003
1132003
3-Amino-1, 2, 4-benzotriazine 4-oxide: characterization of a new metabolite arising from bioreductive processing of the antitumor agent 3-amino-1, 2, 4-benzotriazine 1, 4 …
T Fuchs, G Chowdhury, CL Barnes, KS Gates
The Journal of organic chemistry 66 (1), 107-114, 2001
842001
Metabolism of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease
P Bajpai, MC Sangar, S Singh, W Tang, S Bansal, G Chowdhury, ...
Journal of Biological Chemistry 288 (6), 4436-4451, 2013
802013
DNA strand damage product analysis provides evidence that the tumor cell-specific cytotoxin tirapazamine produces hydroxyl radical and acts as a surrogate for O2
G Chowdhury, V Junnotula, JS Daniels, MM Greenberg, KS Gates
Journal of the American Chemical Society 129 (42), 12870-12877, 2007
722007
Oxidation of methyl and ethyl nitrosamines by cytochrome P450 2E1 and 2B1
G Chowdhury, MW Calcutt, LD Nagy, FP Guengerich
Biochemistry 51 (50), 9995-10007, 2012
702012
Multi-step oxidations catalyzed by cytochrome P450 enzymes: Processive vs. distributive kinetics and the issue of carbonyl oxidation in chemical mechanisms
FP Guengerich, CD Sohl, G Chowdhury
Archives of biochemistry and biophysics 507 (1), 126-134, 2011
702011
DNA Strand Cleavage by the Phenazine Di-N-oxide Natural Product Myxin under Both Aerobic and Anaerobic Conditions
G Chowdhury, U Sarkar, S Pullen, WR Wilson, A Rajapakse, ...
Chemical research in toxicology 25 (1), 197-206, 2012
642012
Oxidation of N-nitrosoalkylamines by human cytochrome P450 2A6: sequential oxidation to aldehydes and carboxylic acids and analysis of reaction steps
G Chowdhury, MW Calcutt, FP Guengerich
Journal of biological chemistry 285 (11), 8031-8044, 2010
642010
Repair of O6-G-Alkyl-O6-G Interstrand Cross-Links by Human O6-Alkylguanine-DNA Alkyltransferase
Q Fang, AM Noronha, SP Murphy, CJ Wilds, JL Tubbs, JA Tainer, ...
Biochemistry 47 (41), 10892-10903, 2008
602008
Enzyme-activated, hypoxia-selective DNA damage by 3-amino-2-quinoxalinecarbonitrile 1, 4-di-N-oxide
G Chowdhury, D Kotandeniya, JS Daniels, CL Barnes, KS Gates
Chemical research in toxicology 17 (11), 1399-1405, 2004
602004
Translesion Synthesis Past the C8- and N2-Deoxyguanosine Adducts of the Dietary Mutagen 2-Amino-3-methylimidazo[4,5-f]quinoline in the NarI Recognition …
JS Stover, G Chowdhury, H Zang, FP Guengerich, CJ Rizzo
Chemical research in toxicology 19 (11), 1506-1517, 2006
522006
Human liver microsomal cytochrome P450 3A enzymes involved in thalidomide 5-hydroxylation and formation of a glutathione conjugate
G Chowdhury, N Murayama, Y Okada, Y Uno, M Shimizu, N Shibata, ...
Chemical research in toxicology 23 (6), 1018-1024, 2010
452010
d-Amino Acid Oxidase Generates Agonists of the Aryl Hydrocarbon Receptor from d-Tryptophan
LP Nguyen, EL Hsu, G Chowdhury, M Dostalek, FP Guengerich, ...
Chemical research in toxicology 22 (12), 1897-1904, 2009
442009
The dihydroxy metabolite of the teratogen thalidomide causes oxidative DNA damage
TH Wani, A Chakrabarty, N Shibata, H Yamazaki, FP Guengerich, ...
Chemical research in toxicology 30 (8), 1622-1628, 2017
422017
Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase η selectively produces a two-base deletion in copying the N2-guanyl adduct of 2 …
JY Choi, JS Stover, KC Angel, G Chowdhury, CJ Rizzo, FP Guengerich
Journal of Biological Chemistry 281 (35), 25297-25306, 2006
422006
Small molecules that mimic the thiol-triggered alkylating properties seen in the natural product leinamycin
T Chatterji, M Kizil, K Keerthi, G Chowdhury, T Pospísil, KS Gates
Journal of the American Chemical Society 125 (17), 4996-4997, 2003
422003
In Vivo Formation of Dihydroxylated and Glutathione Conjugate Metabolites Derived from Thalidomide and 5-Hydroxythalidomide in Humanized TK-NOG Mice
H Yamazaki, H Suemizu, M Shimizu, S Igaya, N Shibata, M Nakamura, ...
Chemical research in toxicology 25 (2), 274-276, 2012
412012
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