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Jacqueline Phan
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A High-Fat/High-Protein, Atkins-Type Diet Exacerbates Clostridioides (Clostridium) difficile Infection in Mice, whereas a High-Carbohydrate Diet Protects
CC Mefferd, SS Bhute, JR Phan, JV Villarama, DM Do, S Alarcia, ...
Msystems 5 (1), 10.1128/msystems. 00765-19, 2020
492020
Effect of the synthetic bile salt analog CamSA on the hamster model of Clostridium difficile infection
A Howerton, CO Seymour, SK Murugapiran, Z Liao, JR Phan, A Estrada, ...
Antimicrobial agents and chemotherapy 62 (10), 10.1128/aac. 02251-17, 2018
292018
An aniline-substituted bile salt analog protects both mice and hamsters from multiple Clostridioides difficile strains
JR Phan, DM Do, MC Truong, C Ngo, JH Phan, SK Sharma, A Schilke, ...
Antimicrobial Agents and Chemotherapy 66 (1), e01435-21, 2022
82022
A high-carbohydrate diet prolongs dysbiosis and Clostridioides difficile carriage and increases delayed mortality in a hamster model of infection
SS Bhute, CC Mefferd, JR Phan, M Ahmed, AE Fox-King, S Alarcia, ...
Microbiology Spectrum 10 (4), e01804-21, 2022
62022
Studies on the Importance of the 7α-, and 12α-hydroxyl groups of N-Aryl-3α, 7α, 12α-trihydroxy-5β-cholan-24-amides on their Antigermination Activity Against a Hypervirulent …
SK Sharma, C Yip, MP Simon, J Phan, E Abel-Santos, SM Firestine
Bioorganic & medicinal chemistry 52, 116503, 2021
52021
Treatment of Clostridium difficile Infections
C Yip, J Phan, E Abel-Santos
52017
Mechanism of germination inhibition of Clostridioides difficile spores by an aniline substituted cholate derivative (CaPA)
C Yip, JR Phan, E Abel-Santos
The Journal of antibiotics 76 (6), 335-345, 2023
32023
A Potential Solution to a Poopy Problem: Bile Salt Analogs as Prophylactics Against Clostridium difficile Infection (CDI)
JR Phan
University of Nevada, Las Vegas, 2017
22017
The design, synthesis, and inhibition of Clostridioides difficile spore germination by acyclic and bicyclic tertiary amide analogs of cholate
SK Sharma, AR Schilke, JR Phan, C Yip, PV Sharma, E Abel-Santos, ...
European Journal of Medicinal Chemistry 261, 115788, 2023
2023
Effects of sexual dimorphism and estrous cycle on C. difficile infections in rodent models
JR Phan, MK Washington, DM Do, TV Mata, M Niamba, E Heredia, ...
bioRxiv, 2023.07. 05.547871, 2023
2023
5, 6-Fused Heterocycle Cholate Derivatives as Spore Germination Inhibitors of Clostridioides difficile
S Sharma, J Phan, E Abel-Santos, S Firestine
2023
Inhibitors of c. difficile spore germination
E Abel-Santos, S Firestine, S Sharma, A Schilke, C Yip, J Phan
US Patent App. 17/941,611, 2023
2023
Poop! There It Is! Anti-Germinants and Biological Variables as Modulators of Clostridioides difficile Infection (CDI)
JR Phan
University of Nevada, Las Vegas, 2023
2023
An Aniline-substituted Bile Salt Analog Protects Both Mice And Hamsters From Multiple Clostridioides difficile Strains
J Phan, DM Do, MC Truong, C Ngo, JH Phan, SK Sharma, A Schilke, ...
Journal of Biological Chemistry 299 (3), S2, 2023
2023
BILE SALT ANALOGS AS PROPHYLACTICS AGAINST CLOSTRIDIOIDES DIFFICILE INFECTION
J Phan
2019 Annual Meeting, 2019
2019
Vancomycin Delays Clindamycin-Induced Fatality in the Hamster Model of Clostridioides [Clostridium] Difficile Infection
AE Fox-King, C Mefferd, JR Phan, NO Nou, E Abel-Santos, BP Hedlund
University of Nevada, Las Vegas; Center for Academic Enrichment and Outreach, 2018
2018
AN ANILINE-SUBSTITUTED BILE SALT ANALOG PROTECTS AGAINST C. DIFFICILE INFECTION
J Phan
2023 Annual Meeting, 0
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Articles 1–17