| Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemia JM Gidday, YG Gasche, JC Copin, AR Shah, RS Perez, SD Shapiro, ... American Journal of Physiology-Heart and Circulatory Physiology 289 (2 …, 2005 | 630 | 2005 |
| Early appearance of activated matrix metalloproteinase-9 after focal cerebral ischemia in mice: a possible role in blood—brain barrier dysfunction Y Gasche, M Fujimura, Y Morita-Fujimura, JC Copin, M Kawase, ... Journal of Cerebral Blood Flow & Metabolism 19 (9), 1020-1028, 1999 | 571 | 1999 |
| Matrix metalloproteinase inhibition prevents oxidative stress-associated blood–brain barrier disruption after transient focal cerebral ischemia Y Gasche, JC Copin, T Sugawara, M Fujimura, PH Chan Journal of Cerebral Blood Flow & Metabolism 21 (12), 1393-1400, 2001 | 481 | 2001 |
| Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice M Fujimura, Y Morita-Fujimura, M Kawase, JC Copin, B Calagui, ... Journal of Neuroscience 19 (9), 3414-3422, 1999 | 384 | 1999 |
| Neurodegeneration in striatum induced by the mitochondrial toxin 3-nitropropionic acid: role of matrix metalloproteinase-9 in early blood-brain barrier disruption? GW Kim, Y Gasche, S Grzeschik, JC Copin, CM Maier, PH Chan Journal of Neuroscience 23 (25), 8733-8742, 2003 | 186 | 2003 |
| Matrix metalloproteinases and diseases of the central nervous system with a special emphasis on ischemic brain Y Gasche, PM Soccal, M Kanemitsu, JC Copin Front Biosci 11 (5), 1289-1301, 2006 | 153 | 2006 |
| Overexpression of copper and zinc superoxide dismutase in transgenic mice prevents the induction and activation of matrix metalloproteinases after cold injury-induced brain trauma Y Morita-Fujimura, M Fujimura, Y Gasche, JC Copin, PH Chan Journal of Cerebral Blood Flow & Metabolism 20 (1), 130-138, 2000 | 149 | 2000 |
| The cytosolic antioxidant, copper/zinc superoxide dismutase, attenuates blood–brain barrier disruption and oxidative cellular injury after photothrombotic cortical ischemia in mice GW Kim, A Lewen, JC Copin, BD Watson, PH Chan Neuroscience 105 (4), 1007-1018, 2001 | 145 | 2001 |
| Excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid GW Kim, JC Copin, M Kawase, SF Chen, S Sato, GT Gobbel, PH Chan Journal of Cerebral Blood Flow & Metabolism 20 (1), 119-129, 2000 | 137 | 2000 |
| Oxidative Stress–Dependent Release of Mitochondrial Cytochrome c after Traumatic Brain Injury A Lewén, M Fujimura, T Sugawara, P Matz, JC Copin, PH Chan Journal of Cerebral Blood Flow & Metabolism 21 (8), 914-920, 2001 | 136 | 2001 |
| Overexpression of copper/zinc superoxide dismutase does not prevent neonatal lethality in mutant mice that lack manganese superoxide dismutase JC Copin, Y Gasche, PH Chan Free Radical Biology and Medicine 28 (10), 1571-1576, 2000 | 135 | 2000 |
| Transgenic mice and knockout mutants in the study of oxidative stress in brain injury PH Chan, CJ Epstein, Y Li, TT Huang, E Carlson, H Kinouchi, G Yang, ... Journal of neurotrauma 12 (5), 815-824, 1995 | 125 | 1995 |
| Copper-zinc superoxide dismutase prevents the early decrease of apurinic/apyrimidinic endonuclease and subsequent DNA fragmentation after transient focal cerebral ischemia in mice M Fujimura, Y Morita-Fujimura, P Narasimhan, JC Copin, M Kawase, ... Stroke 30 (11), 2408-2415, 1999 | 120 | 1999 |
| Copper-zinc superoxide dismutase prevents the early decrease of apurinic/apyrimidinic endonuclease and subsequent DNA fragmentation after transient focal cerebral ischemia in mice M Fujimura, Y Morita-Fujimura, P Narasimhan, JC Copin, M Kawase, ... Stroke 30 (11), 2408-2415, 1999 | 120 | 1999 |
| Cell Death After Exposure to Subarachnoid Hemolysate Correlates Inversely With Expression of CuZn–Superoxide Dismutase PG Matz, JC Copin, PH Chan Stroke 31 (10), 2450-2459, 2000 | 92 | 2000 |
| Role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice JC Copin, MC Goodyear, JM Gidday, AR Shah, E Gascon, A Dayer, ... European Journal of Neuroscience 22 (7), 1597-1608, 2005 | 77 | 2005 |
| Paternal alcohol exposure: developmental and behavioral effects on the offspring of rats M Ledig, R Misslin, E Vogel, A Holownia, JC Copin, G Tholey Neuropharmacology 37 (1), 57-66, 1998 | 75 | 1998 |
| Recombinant tissue plasminogen activator induces blood–brain barrier breakdown by a matrix metalloproteinase‐9‐independent pathway after transient focal cerebral ischemia in mouse JC Copin, DJ Bengualid, RF Da Silva, O Kargiotis, K Schaller, Y Gasche European Journal of Neuroscience 34 (7), 1085-1092, 2011 | 67 | 2011 |
| Treatment with Evasin-3 reduces atherosclerotic vulnerability for ischemic stroke, but not brain injury in mice JC Copin, RF Da Silva, RA Fraga-Silva, L Capettini, S Quintao, S Lenglet, ... Journal of Cerebral Blood Flow & Metabolism 33 (4), 490-498, 2013 | 66 | 2013 |
| Reduced mitochondrial manganese-superoxide dismutase activity exacerbates glutamate toxicity in cultured mouse cortical neurons Y Li, JC Copin, LF Reola, B Calagui, GT Gobbel, SF Chen, S Sato, ... Brain research 814 (1-2), 164-170, 1998 | 63 | 1998 |
