Detection of aggregation-competent tau in neuron-derived extracellular vesicles FX Guix, GT Corbett, DJ Cha, M Mustapic, W Liu, D Mengel, Z Chen, ... International journal of molecular sciences 19 (3), 663, 2018 | 172 | 2018 |
Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α A Roy, M Jana, GT Corbett, S Ramaswamy, JH Kordower, FJ Gonzalez, ... Cell reports 4 (4), 724-737, 2013 | 163 | 2013 |
HMG-CoA reductase inhibitors bind to PPARα to upregulate neurotrophin expression in the brain and improve memory in mice A Roy, M Jana, M Kundu, GT Corbett, SB Rangaswamy, RK Mishra, ... Cell metabolism 22 (2), 253-265, 2015 | 156 | 2015 |
Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP GT Corbett, FJ Gonzalez, K Pahan Proceedings of the National Academy of Sciences 112 (27), 8445-8450, 2015 | 149 | 2015 |
Human brain-derived Aβ oligomers bind to synapses and disrupt synaptic activity in a manner that requires APP Z Wang, RJ Jackson, W Hong, WM Taylor, GT Corbett, A Moreno, W Liu, ... Journal of Neuroscience 37 (49), 11947-11966, 2017 | 136 | 2017 |
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins GT Corbett, Z Wang, W Hong, M Colom-Cadena, J Rose, M Liao, A Asfaw, ... Acta neuropathologica 139, 503-526, 2020 | 131 | 2020 |
Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer’s pathology SB Rangasamy, M Jana, A Roy, GT Corbett, M Kundu, S Chandra, ... The Journal of Clinical Investigation 128 (10), 4297-4312, 2018 | 112 | 2018 |
Altered spinal microRNA‐146a and the microRNA‐183 cluster contribute to osteoarthritic pain in knee joints X Li, JS Kroin, R Kc, G Gibson, D Chen, GT Corbett, K Pahan, S Fayyaz, ... Journal of Bone and Mineral Research 28 (12), 2512-2522, 2013 | 95 | 2013 |
Cellular prion protein mediates the disruption of hippocampal synaptic plasticity by soluble tau in vivo T Ondrejcak, I Klyubin, GT Corbett, G Fraser, W Hong, AJ Mably, ... Journal of Neuroscience 38 (50), 10595-10606, 2018 | 87 | 2018 |
Cryopreservation maintains functionality of human iPSC dopamine neurons and rescues parkinsonian phenotypes in vivo DR Wakeman, BM Hiller, DJ Marmion, CW McMahon, GT Corbett, ... Stem cell reports 9 (1), 149-161, 2017 | 80 | 2017 |
Extracellular forms of Aβ and tau from iPSC models of Alzheimer’s disease disrupt synaptic plasticity NW Hu, GT Corbett, S Moore, I Klyubin, TT O’Malley, DM Walsh, ... Cell Reports 23 (7), 1932-1938, 2018 | 78 | 2018 |
Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense GT Corbett, A Roy, K Pahan The Journal of Immunology 189 (2), 1002-1013, 2012 | 67 | 2012 |
Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications … GT Corbett, A Roy, K Pahan Journal of Biological Chemistry 288 (12), 8299-8312, 2013 | 59 | 2013 |
Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator … A Ghosh, GT Corbett, FJ Gonzalez, K Pahan Journal of Biological Chemistry 287 (46), 38922-38935, 2012 | 57 | 2012 |
Intranasal delivery of NEMO-binding domain peptide prevents memory loss in a mouse model of Alzheimer’s disease SB Rangasamy, GT Corbett, A Roy, KK Modi, DA Bennett, EJ Mufson, ... Journal of Alzheimer's Disease 47 (2), 385-402, 2015 | 48 | 2015 |
Soluble tau aggregates inhibit synaptic long-term depression and amyloid β-facilitated LTD in vivo T Ondrejcak, NW Hu, Y Qi, I Klyubin, GT Corbett, G Fraser, MS Perkinton, ... Neurobiology of Disease 127, 582-590, 2019 | 34 | 2019 |
Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer’s disease TF Musial, E Molina-Campos, LA Bean, N Ybarra, R Borenstein, ... Neurobiology of learning and memory 154, 141-157, 2018 | 18 | 2018 |
PrP-grafted antibodies bind certain amyloid β-protein aggregates, but do not prevent toxicity D Mengel, W Hong, GT Corbett, W Liu, A DeSousa, L Solforosi, C Fang, ... Brain research 1710, 125-135, 2019 | 14 | 2019 |
The native form of α‐Synuclein: Monomer, tetramer, or a combination in equilibrium GT Corbett, JH Kordower Movement Disorders 30 (14), 1870-1870, 2015 | 7 | 2015 |
Regulation of CREB and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α A Roy, M Jana, GT Corbett, S Ramaswamy, JH Kordower, FJ Gonzalez, ... Cell reports 4 (4), 724, 2013 | 6 | 2013 |