Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 M Tahiliani, KP Koh, Y Shen, WA Pastor, H Bandukwala, Y Brudno, ... Science 324 (5929), 930-935, 2009 | 6556 | 2009 |
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells WA Pastor, UJ Pape, Y Huang, HR Henderson, R Lister, M Ko, ... Nature 473 (7347), 394-397, 2011 | 968 | 2011 |
Enhancing microvascular formation and vessel maturation through temporal control over multiple pro-angiogenic and pro-maturation factors Y Brudno, AB Ennett-Shepard, RR Chen, M Aizenberg, DJ Mooney Biomaterials 34 (36), 9201-9209, 2013 | 226 | 2013 |
Comparison of biomaterial delivery vehicles for improving acute retention of stem cells in the infarcted heart ET Roche, CL Hastings, SA Lewin, DE Shvartsman, Y Brudno, ... Biomaterials 35 (25), 6850-6858, 2014 | 184 | 2014 |
DNA-templated polymerization of side-chain-functionalized peptide nucleic acid aldehydes RE Kleiner, Y Brudno, ME Birnbaum, DR Liu Journal of the American Chemical Society 130 (14), 4646-4659, 2008 | 177 | 2008 |
On-demand drug delivery from local depots Y Brudno, DJ Mooney Journal of Controlled Release 219, 8-17, 2015 | 160 | 2015 |
Platelet‐inspired nanocells for targeted heart repair after ischemia/reperfusion injury T Su, K Huang, H Ma, H Liang, PU Dinh, J Chen, D Shen, TA Allen, ... Advanced functional materials 29 (4), 1803567, 2019 | 128 | 2019 |
Recent progress toward the templated synthesis and directed evolution of sequence-defined synthetic polymers Y Brudno, DR Liu Chemistry & biology 16 (3), 265-276, 2009 | 122 | 2009 |
An in vitro translation, selection and amplification system for peptide nucleic acids Y Brudno, ME Birnbaum, RE Kleiner, DR Liu Nature chemical biology 6 (2), 148-155, 2010 | 116 | 2010 |
Refilling drug delivery depots through the blood Y Brudno, EA Silva, CJ Kearney, SA Lewin, A Miller, KD Martinick, ... Proceedings of the National Academy of Sciences 111 (35), 12722-12727, 2014 | 108 | 2014 |
Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells P Agarwalla, EA Ogunnaike, S Ahn, KA Froehlich, A Jansson, FS Ligler, ... Nature biotechnology 40 (8), 1250-1258, 2022 | 107 | 2022 |
Three-Dimensional Human Tissue Models That Incorporate Diabetic Foot Ulcer-Derived Fibroblasts Mimic In Vivo Features of Chronic Wounds AG Maione, Y Brudno, O Stojadinovic, LK Park, A Smith, A Tellechea, ... Tissue Engineering Part C: Methods 21 (5), 499-508, 2015 | 107 | 2015 |
Sustained delivery of VEGF maintains innervation and promotes reperfusion in ischemic skeletal muscles via NGF/GDNF signaling D Shvartsman, H Storrie-White, K Lee, C Kearney, Y Brudno, N Ho, ... Molecular Therapy 22 (7), 1243-1253, 2014 | 103 | 2014 |
Replenishable drug depot to combat post-resection cancer recurrence Y Brudno, MJ Pezone, TK Snyder, O Uzun, CT Moody, M Aizenberg, ... Biomaterials 178, 373-382, 2018 | 62 | 2018 |
Click cross-linking improves retention and targeting of refillable alginate depots CT Moody, S Palvai, Y Brudno Acta biomaterialia 112, 112-121, 2020 | 41 | 2020 |
In vivo targeting through click chemistry Y Brudno, RM Desai, BJ Kwee, NS Joshi, M Aizenberg, DJ Mooney ChemMedChem 10 (4), 617-620, 2015 | 41 | 2015 |
Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo Y Shamis, EA Silva, KJ Hewitt, Y Brudno, S Levenberg, DJ Mooney, ... Plos one 8 (12), e83755, 2013 | 37 | 2013 |
Scaffold‐mediated static transduction of T cells for CAR‐T cell therapy P Agarwalla, EA Ogunnaike, S Ahn, FS Ligler, G Dotti, Y Brudno Advanced healthcare materials 9 (14), 2000275, 2020 | 22 | 2020 |
Clickable, acid labile immunosuppressive prodrugs for in vivo targeting H Wang, MC Sobral, T Snyder, Y Brudno, VS Gorantla, DJ Mooney Biomaterials science 8 (1), 266-277, 2020 | 19 | 2020 |
Refillable drug delivery devices and methods of use thereof Y Brudno, CJ Kearney, E Silva, M Aizenberg, B Kwee, R Desai, NS Joshi, ... US Patent App. 14/878,578, 2016 | 17 | 2016 |