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Usha Viswanathan
Usha Viswanathan
Janssen Scientist, Computer Aided Drug Design
Verified email at its.jnj.com
Title
Cited by
Cited by
Year
Targeting the multifunctional HBV core protein as a potential cure for chronic hepatitis B
U Viswanathan, N Mani, Z Hu, H Ban, Y Du, J Hu, J Chang, JT Guo
Antiviral research 182, 104917, 2020
762020
Identification of a novel inhibitor of dengue virus protease through use of a virtual screening drug discovery Web portal
U Viswanathan, SM Tomlinson, JM Fonner, SA Mock, SJ Watowich
Journal of chemical information and modeling 54 (10), 2816-2825, 2014
562014
Discovery and mechanistic study of a novel human-stimulator-of-interferon-genes agonist
X Zhang, B Liu, L Tang, Q Su, N Hwang, M Sehgal, J Cheng, J Ma, ...
ACS infectious diseases 5 (7), 1139-1149, 2019
502019
Importance of dynamic hydrogen bonds and reorientation barriers in proton transport
C Nagamani, U Viswanathan, C Versek, MT Tuominen, SM Auerbach, ...
Chemical communications 47 (23), 6638-6640, 2011
342011
Vibrational predissociation spectroscopy and theory of Ar-tagged, protonated Imidazole (Im) Im1–3H+· Ar clusters
HK Gerardi, GH Gardenier, U Viswanathan, SM Auerbach, MA Johnson
Chemical Physics Letters 501 (4-6), 172-178, 2011
242011
Modeling energy landscapes of proton motion in nonaqueous, tethered proton wires
U Viswanathan, D Basak, D Venkataraman, JT Fermann, SM Auerbach
The Journal of Physical Chemistry A 115 (21), 5423-5434, 2011
212011
CpAMs induce assembly of HBV capsids with altered electrophoresis mobility: Implications for mechanism of inhibiting pgRNA packaging
S Wu, Y Luo, U Viswanathan, J Kulp, J Cheng, Z Hu, Q Xu, Y Zhou, ...
Antiviral research 159, 1-12, 2018
202018
Modeling proton jumps in HY zeolite: effects of acid site heterogeneity
U Viswanathan, JT Fermann, LK Toy, SM Auerbach, T Vreven, MJ Frisch
The Journal of Physical Chemistry C 111 (49), 18341-18347, 2007
192007
Structure-based design of selective, orally available salt-inducible kinase inhibitors that stimulate bone formation in mice
T Sato, CDC Andrade, SH Yoon, Y Zhao, WJ Greenlee, PC Weber, ...
Proceedings of the National Academy of Sciences 119 (50), e2214396119, 2022
172022
Amino acid residues at core protein dimer-dimer interface modulate multiple steps of hepatitis B virus replication and HBeAg biogenesis
H Liu, J Cheng, U Viswanathan, J Chang, F Lu, JT Guo
PLoS pathogens 17 (11), e1010057, 2021
172021
Profiling the circulating mRNA transcriptome in human liver disease
A Sayeed, BE Dalvano, DE Kaplan, U Viswanathan, J Kulp, AH Janneh, ...
Oncotarget 11 (23), 2216, 2020
142020
Modeling nonaqueous proton wires built from helical peptides: biased proton transfer driven by helical dipoles
GE López, I Colón-Díaz, A Cruz, S Ghosh, SB Nicholls, U Viswanathan, ...
The Journal of Physical Chemistry A 116 (4), 1283-1288, 2012
142012
Simulating hydrogen-bond clustering and phase behaviour of imidazole oligomers
JA Harvey, D Basak, D Venkataraman, SM Auerbach
Molecular Physics 110 (9-10), 957-966, 2012
132012
Identification of hepatitis B virus core protein residues critical for capsid assembly, pgRNA encapsidation and resistance to capsid assembly modulators
Y Luo, J Cheng, Z Hu, H Ban, S Wu, N Hwang, J Kulp, Y Li, Y Du, J Chang, ...
Antiviral Research 191, 105080, 2021
102021
A putative amphipathic alpha helix in hepatitis B virus small envelope protein plays a critical role in the morphogenesis of subviral particles
S Yang, Z Shen, Y Kang, L Sun, U Viswanathan, H Guo, T Zhou, X Dai, ...
Journal of Virology 95 (8), 10.1128/jvi. 02399-20, 2021
52021
4-Oxooctahydroquinoline-1 (2H)-carboxamides as hepatitis B virus (HBV) capsid core protein assembly modulators
N Hwang, H Ban, S Wu, K McGuire, E Hernandez, J Chen, Q Zhao, ...
Bioorganic & medicinal chemistry letters 58, 128518, 2022
42022
Precision Discovery of Novel Inhibitors of Human Cancer Target HsMetAP1 from Vast Unexplored Metagenomic Diversity
OW Liu, S Akers, G Alvarez, S Brown, W Cai, Z Charlop-Powers, ...
bioRxiv, 2022.06. 11.495772, 2022
12022
Small-molecule inhibitors of dengue virus proteases
SJ Watowich, U Viswanathan
US Patent 9,408,813, 2016
12016
Identification of novel tetrahydroquinoxaline derived phenyl ureas as modulators of the hepatitis B virus nucleocapsid assembly
N Hwang, S Wu, H Ban, H Luo, J Ma, J Cheng, Q Zhao, JA Laney, N Du, ...
European Journal of Medicinal Chemistry 259, 115634, 2023
2023
Molecular modeling of proton transfer mechanisms, energetics and rates in zeolites and proton exchange membranes
U Viswanathan
University of Massachusetts Amherst, 2011
2011
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