| TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals RK Adapala, RJ Thoppil, DJ Luther, S Paruchuri, JG Meszaros, ... Journal of molecular and cellular cardiology 54, 45-52, 2013 | 213 | 2013 |
| Leukotriene B4 is a physiologically relevant endogenous peroxisome proliferator-activated receptor-α agonist VR Narala, RK Adapala, MV Suresh, TG Brock, M Peters-Golden, ... Journal of Biological Chemistry 285 (29), 22067-22074, 2010 | 162 | 2010 |
| Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy RK Adapala, RJ Thoppil, K Ghosh, HC Cappelli, AC Dudley, S Paruchuri, ... Oncogene 35 (3), 314-322, 2016 | 148 | 2016 |
| Absence of type VI collagen paradoxically improves cardiac function, structure, and remodeling after myocardial infarction DJ Luther, CK Thodeti, PE Shamhart, RK Adapala, C Hodnichak, ... Circulation research 110 (6), 851-856, 2012 | 118 | 2012 |
| PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells RK Adapala, PK Talasila, IN Bratz, DX Zhang, M Suzuki, JG Meszaros, ... American Journal of Physiology-Heart and Circulatory Physiology 301 (3 …, 2011 | 115 | 2011 |
| TRPV4 channels regulate tumor angiogenesis via modulation of Rho/Rho kinase pathway RJ Thoppil, HC Cappelli, RK Adapala, AK Kanugula, S Paruchuri, ... Oncotarget 7 (18), 25849, 2016 | 86 | 2016 |
| Primary cilia regulates the directional migration and barrier integrity of endothelial cells through the modulation of hsp27 dependent actin cytoskeletal organization TJ Jones, RK Adapala, WJ Geldenhuys, C Bursley, WA AbouAlaiwi, ... Journal of cellular physiology 227 (1), 70-76, 2012 | 84 | 2012 |
| Cysteinyl leukotrienes regulate endothelial cell inflammatory and proliferative signals through CysLT2 and CysLT1 receptors E Duah, RK Adapala, N Al-Azzam, V Kondeti, F Gombedza, CK Thodeti, ... Scientific reports 3 (1), 3274, 2013 | 81 | 2013 |
| TRPV4 deletion protects heart from myocardial infarction-induced adverse remodeling via modulation of cardiac fibroblast differentiation RK Adapala, AK Kanugula, S Paruchuri, WM Chilian, CK Thodeti Basic research in cardiology 115, 1-14, 2020 | 74 | 2020 |
| TRPV4 channel activation selectively inhibits tumor endothelial cell proliferation RJ Thoppil, RK Adapala, HC Cappelli, V Kondeti, AC Dudley, ... Scientific reports 5 (1), 14257, 2015 | 68 | 2015 |
| Hyperglycemia enhances function and differentiation of adult rat cardiac fibroblasts PE Shamhart, DJ Luther, RK Adapala, JE Bryant, KA Petersen, ... Canadian journal of physiology and pharmacology 92 (7), 598-604, 2014 | 56 | 2014 |
| Mechanosensitive TRPV4 channels stabilize VE-cadherin junctions to regulate tumor vascular integrity and metastasis HC Cappelli, AK Kanugula, RK Adapala, V Amin, P Sharma, P Midha, ... Cancer letters 442, 15-20, 2019 | 53 | 2019 |
| Curcumin is not a ligand for peroxisome proliferator-activated receptor-γ VR Narala, MR Smith, RK Adapala, R Ranga, K Panati, BB Moore, T Leff, ... Gene therapy & molecular biology 13 (1), 20, 2009 | 53 | 2009 |
| Upregulation of thrombospondin-1 expression by leptin in vascular smooth muscle cells via JAK2-and MAPK-dependent pathways RJ Chavez, RM Haney, RH Cuadra, R Ganguly, RK Adapala, CK Thodeti, ... American Journal of Physiology-Cell Physiology 303 (2), C179-C191, 2012 | 49 | 2012 |
| Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis E Duah, LR Teegala, V Kondeti, RK Adapala, VG Keshamouni, ... Proceedings of the National Academy of Sciences 116 (1), 199-204, 2019 | 47 | 2019 |
| Endothelial TRPV4 channels prevent tumor growth and metastasis via modulation of tumor angiogenesis and vascular integrity AK Kanugula, RK Adapala, A Jamaiyar, N Lenkey, BD Guarino, W Liedtke, ... Angiogenesis 24, 647-656, 2021 | 42 | 2021 |
| Novel noncanonical regulation of soluble VEGF/VEGFR2 signaling by mechanosensitive ion channel TRPV4 AK Kanugula, RK Adapala, P Midha, HC Cappelli, JG Meszaros, ... The FASEB Journal 33 (1), 195, 2019 | 35 | 2019 |
| Extracellular vesicles from pathological microenvironment induce endothelial cell transformation and abnormal angiogenesis via modulation of TRPV4 channels BD Guarino, RK Adapala, AK Kanugula, NM Lenkey, JA Dougherty, ... Frontiers in cell and developmental biology 7, 344, 2019 | 19 | 2019 |
| TRPV4 mechanotransduction in fibrosis RK Adapala, V Katari, LR Teegala, S Thodeti, S Paruchuri, CK Thodeti Cells 10 (11), 3053, 2021 | 18 | 2021 |
| Tumor-derived extracellular vesicles induce abnormal angiogenesis via TRPV4 downregulation and subsequent activation of YAP and VEGFR2 B Guarino, V Katari, R Adapala, N Bhavnani, J Dougherty, M Khan, ... Frontiers in Bioengineering and Biotechnology 9, 790489, 2021 | 13 | 2021 |
