A rapid method of cloning functional variable-region antibody genes in Escherichia coli as single-chain immunotoxins. VK Chaudhary, JK Batra, MG Gallo, MC Willingham, DJ FitzGerald, ... Proceedings of the National Academy of Sciences 87 (3), 1066-1070, 1990 | 367 | 1990 |
Direct correlation between DNA topoisomerase II activity and cytotoxicity in adriamycin-sensitive and-resistant P388 leukemia cell lines AM Deffie, JK Batra, GJ Goldenberg Cancer research 49 (1), 58-62, 1989 | 346 | 1989 |
Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin … AM Deffie, T Alam, C Seneviratne, SW Beenken, JK Batra, TC Shea, ... Cancer Research 48 (13), 3595-3602, 1988 | 257 | 1988 |
Recombinant anti-erbB2 immunotoxins containing Pseudomonas exotoxin. JK Batra, PG Kasprzyk, RE Bird, I Pastan, CR King Proceedings of the National Academy of Sciences 89 (13), 5867-5871, 1992 | 213 | 1992 |
Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium K Chang, LH Pai, JK Batra, I Pastan, MC Willingham Cancer research 52 (1), 181-186, 1992 | 193 | 1992 |
Anti-Tac (Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells. JK Batra, D FitzGerald, M Gately, VK Chaudhary, I Pastan Journal of Biological Chemistry 265 (25), 15198-15202, 1990 | 155 | 1990 |
Single-Chain Immunotoxins Directed at the Human Transferrin Receptor Containing Pseudomonas Exotoxin A or Diphtheria Toxin: Anti-TFR(Fv)-PE40 and DT388 … JK Batra, DJ Fitzgerald, VK Chaudhary, I Pastan Molecular and cellular biology 11 (4), 2200-2205, 1991 | 144 | 1991 |
The cytotoxic activity of ribosome-inactivating protein saporin-6 is attributed to its rRNA N-glycosidase and internucleosomal DNA fragmentation activities S Bagga, D Seth, JK Batra Journal of Biological Chemistry 278 (7), 4813-4820, 2003 | 113 | 2003 |
Anti-tumor activities of immunotoxins made of monoclonal antibody B3 and various forms of Pseudomonas exotoxin. LH Pai, JK Batra, DJ FitzGerald, MC Willingham, I Pastan Proceedings of the National Academy of Sciences 88 (8), 3358-3362, 1991 | 109 | 1991 |
Antitumor activity in mice of an immunotoxin made with anti-transferrin receptor and a recombinant form of Pseudomonas exotoxin. JK Batra, Y Jinno, VK Chaudhary, T Kondo, MC Willingham, DJ FitzGerald, ... Proceedings of the National Academy of Sciences 86 (21), 8545-8549, 1989 | 109 | 1989 |
Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: relative importance of the two toxin disulfide bonds RJ Kreitman, JK Batra, S Seetharam, VK Chaudhary, DJ FitzGerald, ... Bioconjugate chemistry 4 (2), 112-120, 1993 | 102 | 1993 |
Interaction of human pancreatic ribonuclease with human ribonuclease inhibitor: generation of inhibitor-resistant cytotoxic variants D Gaur, S Swaminathan, JK Batra Journal of Biological Chemistry 276 (27), 24978-24984, 2001 | 86 | 2001 |
Antimicrobial activity of human eosinophil granule proteins: involvement in host defence against pathogens A Malik, JK Batra Critical reviews in microbiology 38 (2), 168-181, 2012 | 82 | 2012 |
Ribosome inactivating protein saporin induces apoptosis through mitochondrial cascade, independent of translation inhibition D Sikriwal, P Ghosh, JK Batra The International Journal of Biochemistry & Cell Biology 40 (12), 2880-2888, 2008 | 81 | 2008 |
Inclusion of a furin-sensitive spacer enhances the cytotoxicity of ribotoxin restrictocin containing recombinant single-chain immunotoxins A Goyal, JK Batra Biochemical Journal 345 (2), 247-254, 2000 | 66 | 2000 |
Mycobacterium tuberculosis ClpC1: Characterization and role of the N‐terminal domain in its function NP Kar, D Sikriwal, P Rath, RK Choudhary, JK Batra The FEBS journal 275 (24), 6149-6158, 2008 | 58 | 2008 |
Structure-function studies with derivatives of 6-benzyl-1, 3-benzodioxole, a new class of synthetic compounds which inhibit tubulin polymerization and mitosis. JK Batra, L Jurd, E Hamel Molecular pharmacology 27 (1), 94-102, 1985 | 55 | 1985 |
Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin I Pastan, V Chaudhary, D FitzGerald, J Batra US Patent 6,099,842, 2000 | 53 | 2000 |
Antitumor effects of B3-PE and B3-LysPE40 in a nude mouse model of human breast cancer and the evaluation of B3-PE toxicity in monkeys LH Pai, JK Batra, DJ FitzGerald, MC Willingham, I Pastan Cancer research 52 (11), 3189-3193, 1992 | 48 | 1992 |
Expression of ribonucleolytic toxin restrictocin in Escherichia coli: purification and characterization D Rathore, SK Nayak, JK Batra FEBS letters 392 (3), 259-262, 1996 | 47 | 1996 |