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Pradeepkumar PI
Pradeepkumar PI
Professor of Chemistry, IIT Bombay
Verified email at chem.iitb.ac.in
Title
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Cited by
Year
Thioflavin T as an efficient inducer and selective fluorescent sensor for the human telomeric G-quadruplex DNA
J Mohanty, N Barooah, V Dhamodharan, S Harikrishna, PI Pradeepkumar, ...
Journal of the American Chemical Society 135 (1), 367-376, 2013
6112013
Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook
S Shukla, CS Sumaria, PI Pradeepkumar
ChemMedChem 5 (3), 328-349, 2010
2362010
A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H
E Zamaratski, PI Pradeepkumar, J Chattopadhyaya
Journal of biochemical and biophysical methods 48 (3), 189-208, 2001
1812001
DNA-catalyzed formation of nucleopeptide linkages
PI Pradeepkumar, C Hobartner, DA Baum, SK Silverman
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH- 47 (9), 1753, 2008
1012008
Selective G-quadruplex DNA stabilizing agents based on bisquinolinium and bispyridinium derivatives of 1, 8-naphthyridine
V Dhamodharan, S Harikrishna, C Jagadeeswaran, K Halder, ...
The Journal of organic chemistry 77 (1), 229-242, 2012
772012
Synthesis of [Ru(phen)2dppz]2+-Tethered Oligo-DNA and Studies on the Metallointercalation Mode into the DNA Duplex
D Ossipov, PI Pradeepkumar, M Holmer, J Chattopadhyaya
Journal of the American Chemical Society 123 (15), 3551-3562, 2001
762001
Synthesis, Physicochemical and Biochemical Studies of 1 ‘, 2 ‘-Oxetane Constrained Adenosine and Guanosine Modified Oligonucleotides, and Their Comparison with Those of the …
PI Pradeepkumar, P Cheruku, O Plashkevych, P Acharya, S Gohil, ...
Journal of the American Chemical Society 126 (37), 11484-11499, 2004
642004
Specific Stabilization of c-MYC and c-KIT G-Quadruplex DNA Structures by Indolylmethyleneindanone Scaffolds
KV Diveshkumar, S Sakrikar, F Rosu, S Harikrishna, V Gabelica, ...
Biochemistry 55 (25), 3571-3585, 2016
632016
Specific recognition of promoter G-quadruplex DNAs by small molecule ligands and light-up probes
V Dhamodharan, PI Pradeepkumar
ACS Chemical Biology 14 (10), 2102-2114, 2019
582019
Topology specific stabilization of promoter over telomeric G-quadruplex DNAs by bisbenzimidazole carboxamide derivatives
V Dhamodharan, S Harikrishna, AC Bhasikuttan, PI Pradeepkumar
ACS chemical biology 10 (3), 821-833, 2015
582015
An Electrochemical Probe of DNA Stacking in an Antisense Oligonucleotide Containing a C3′‐endo‐Locked Sugar
EM Boon, JK Barton, PI Pradeepkumar, J Isaksson, C Petit, ...
Angewandte Chemie 114 (18), 3552-3555, 2002
522002
Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to …
PI Pradeepkumar, NV Amirkhanov, J Chattopadhyaya
Organic & biomolecular chemistry 1 (1), 81-92, 2003
492003
Targeting Promoter G‐Quadruplex DNAs by Indenopyrimidine‐Based Ligands
KV Diveshkumar, S Sakrikar, S Harikrishna, V Dhamodharan, ...
ChemMedChem 9 (12), 2754-2765, 2014
442014
G-quadruplex forming structural motifs in the genome of Deinococcus radiodurans and their regulatory roles in promoter functions
S Kota, V Dhamodharan, PI Pradeepkumar, HS Misra
Applied microbiology and biotechnology 99, 9761-9769, 2015
432015
DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates
OY Wong, PI Pradeepkumar, SK Silverman
Biochemistry 50 (21), 4741-4749, 2011
402011
Oxetane modified, conformationally constrained, antisense oligodeoxyribonucleotides function efficiently as gene silencing molecules
JB Opalinska, A Kalota, LK Gifford, P Lu, KY Jen, PI Pradeepkumar, ...
Nucleic Acids Research 32 (19), 5791-5799, 2004
392004
Synthesis, Gene Silencing, and Molecular Modeling Studies of 4′-C-Aminomethyl-2′-O-methyl Modified Small Interfering RNAs
KR Gore, GN Nawale, S Harikrishna, VG Chittoor, SK Pandey, ...
The Journal of Organic Chemistry 77 (7), 3233-3245, 2012
372012
Oxetane modified antisense oligonucleotides promote RNase H cleavage of the complementary RNA strand in the hybrid duplex as efficiently as the native, and offer improved …
PI Pradeepkumar, J Chattopadhyaya
Journal of the Chemical Society, Perkin Transactions 2, 2074-2083, 2001
372001
Conformation-specific cleavage of antisense oligonucleotide-RNA duplexes by RNase H
PI Pradeepkumar, E Zamaratski, A Földesi, J Chattopadhyaya
Journal of the Chemical Society, Perkin Transactions 2, 402-408, 2001
352001
Site-selective depurination by a periodate-dependent deoxyribozyme
C Höbartner, PI Pradeepkumar, SK Silverman
Chemical communications, 2255-2257, 2007
332007
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