Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides. RF Schinazi, RM Lloyd, MH Nguyen, DL Cannon, A McMillan, N Ilksoy, ... Antimicrobial agents and chemotherapy 37 (4), 875-881, 1993 | 474 | 1993 |
Activities of the four optical isomers of 2', 3'-dideoxy-3'-thiacytidine (BCH-189) against human immunodeficiency virus type 1 in human lymphocytes. RF Schinazi, CK Chu, A Peck, A McMillan, R Mathis, D Cannon, LS Jeong, ... Antimicrobial Agents and Chemotherapy 36 (3), 672-676, 1992 | 408 | 1992 |
Chemistry and antiviral activities of acyclonucleosides CK Chu, SJ Cutler Journal of heterocyclic chemistry 23 (2), 289-319, 1986 | 359 | 1986 |
Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2', 3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication. CN Chang, SL Doong, JH Zhou, JW Beach, LS Jeong, CK Chu, CH Tsai, ... Journal of Biological Chemistry 267 (20), 13938-13942, 1992 | 353 | 1992 |
Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2 J Friedman, WK Cho, CK Chu, KS Keedy, NM Archin, DM Margolis, J Karn Journal of virology 85 (17), 9078-9089, 2011 | 338 | 2011 |
Use of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil as a novel antiviral agent for hepatitis B virus and Epstein-Barr virus. CK Chu, T Ma, K Shanmuganathan, C Wang, Y Xiang, SB Pai, GQ Yao, ... Antimicrobial agents and chemotherapy 39 (4), 979-981, 1995 | 324 | 1995 |
Ribonucleoside analogue that blocks replication of bovine viral diarrhea and hepatitis C viruses in culture LJ Stuyver, T Whitaker, TR McBrayer, BI Hernandez-Santiago, S Lostia, ... Antimicrobial agents and chemotherapy 47 (1), 244-254, 2003 | 270 | 2003 |
Nucleosides and nucleotides as antitumor and antiviral agents DC Baker, C Chu Springer, 2013 | 268 | 2013 |
Nucleosidesand Nucleotides as Antitumor and Antiviral Agents CK Chu, DC Baker, RP Panzica Journal of Medicinal Chemistry 37 (10), 1543-1543, 1994 | 268* | 1994 |
Synthesis of enantiomerically pure (2'R, 5'S)-(-)-1-(2-hydroxymethyloxathiolan-5-yl) cytosine as a potent antiviral agent against hepatitis B virus (HBV) and human … JW Beach, LS Jeong, AJ Alves, D Pohl, HO Kim, CN Chang, SL Doong, ... The Journal of Organic Chemistry 57 (8), 2217-2219, 1992 | 250 | 1992 |
Fluorinated nucleosides: Synthesis and biological implication P Liu, A Sharon, CK Chu Journal of fluorine chemistry 129 (9), 743-766, 2008 | 231 | 2008 |
Anthraquinones as a new class of antiviral agents against human immunodeficiency virus RF Schinazi, CK Chu, JR Babu, BJ Oswald, V Saalmann, DL Cannon, ... Antiviral research 13 (5), 265-272, 1990 | 231 | 1990 |
Asymmetric synthesis and biological evaluation of. beta.-L-(2R, 5S)-and. alpha.-L-(2R, 5R)-1, 3-oxathiolane-pyrimidine and-purine nucleosides as potential anti-HIV agents LS Jeong, RF Schinazi, JW Beach, HO Kim, S Nampalli, ... Journal of medicinal chemistry 36 (2), 181-195, 1993 | 224 | 1993 |
Therapy for hepatitis B virus infection; antiproliferative agents; antitumor agents; anticancer agents RF Schinazi, DC Liotta, CK Chu, JJ McAtee, J Shi, Y Choi, K Lee, ... US Patent 7,307,065, 2007 | 220* | 2007 |
2′-fluoronucleosides RF Schinazi, DC Liotta, CK Chu, JJ McAtee, J Shi, Y Choi, K Lee, ... US Patent 6,911,424, 2005 | 219 | 2005 |
2-fluoronucleosides RF Schinazi, DC Liotta, CK Chu, JJ McAtee, J Shi, Y Choi, K Lee, ... US Patent 8,168,583, 2012 | 218* | 2012 |
2'-fluoronucleosides RF Schinazi, DC Liotta, CK Chu, JJ McAtee US Patent App. 13/437,676, 2012 | 213* | 2012 |
Therapy for hepatitis B virus infection; antiproliferative agents; antitumor agents; anticancer agents; HIV RF Schinazi, DC Liotta, CK Chu, JJ McAtee, J Shi, Y Choi, K Lee, ... US Patent App. 11/942,551, 2007 | 212* | 2007 |
Purine or pyrimidine base derivatives; anticancer, antitumor and antiproliferative agents; treating hiv and hepatitis RF Schinazi, DC Liotta, CK Chu, JJ McAtee, J Shi, Y Choi, K Lee, ... US Patent 6,348,587, 2002 | 211* | 2002 |
Anticancer activity of β-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration KL Grove, X Guo, SH Liu, Z Gao, CK Chu, YC Cheng Cancer Research 55 (14), 3008-3011, 1995 | 202 | 1995 |