| Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis D Sebastián, MI Hernández-Alvarez, J Segalés, E Sorianello, JP Muñoz, ... Proceedings of the National Academy of Sciences 109 (14), 5523-5528, 2012 | 687 | 2012 |
| The gut microbiota modulates host energy and lipid metabolism in mice [S] VR Velagapudi, R Hezaveh, CS Reigstad, P Gopalacharyulu, L Yetukuri, ... Journal of lipid research 51 (5), 1101-1112, 2010 | 662 | 2010 |
| Metabolome in progression to Alzheimer's disease M Orešič, T Hyötyläinen, SK Herukka, M Sysi-Aho, I Mattila, ... Translational psychiatry 1 (12), e57-e57, 2011 | 285 | 2011 |
| Association of lipidome remodeling in the adipocyte membrane with acquired obesity in humans KH Pietiläinen, T Rog, T Seppänen-Laakso, S Virtue, P Gopalacharyulu, ... PLoS biology 9 (6), e1000623, 2011 | 272 | 2011 |
| Deficient endoplasmic reticulum-mitochondrial phosphatidylserine transfer causes liver disease MI Hernández-Alvarez, D Sebastián, S Vives, S Ivanova, P Bartoccioni, ... Cell 177 (4), 881-895. e17, 2019 | 260 | 2019 |
| Algorithms and tools for the preprocessing of LC–MS metabolomics data S Castillo, P Gopalacharyulu, L Yetukuri, M Orešič Chemometrics and Intelligent Laboratory Systems 108 (1), 23-32, 2011 | 210 | 2011 |
| Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids M Orešič, T Hyötyläinen, A Kotronen, P Gopalacharyulu, H Nygren, ... Diabetologia 56, 2266-2274, 2013 | 165 | 2013 |
| Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open … J Guinney, T Wang, TD Laajala, KK Winner, JC Bare, EC Neto, SA Khan, ... The Lancet Oncology 18 (1), 132-142, 2017 | 161 | 2017 |
| Noninvasive detection of nonalcoholic steatohepatitis using clinical markers and circulating levels of lipids and metabolites Y Zhou, M Orešič, M Leivonen, P Gopalacharyulu, J Hyysalo, J Arola, ... Clinical Gastroenterology and Hepatology 14 (10), 1463-1472. e6, 2016 | 143 | 2016 |
| Drug target commons: a community effort to build a consensus knowledge base for drug-target interactions J Tang, B Ravikumar, Z Alam, A Rebane, M Vähä-Koskela, G Peddinti, ... Cell chemical biology 25 (2), 224-229. e2, 2018 | 127 | 2018 |
| Early metabolic markers identify potential targets for the prevention of type 2 diabetes G Peddinti, J Cobb, L Yengo, P Froguel, J Kravić, B Balkau, T Tuomi, ... Diabetologia 60 (9), 1740-1750, 2017 | 121 | 2017 |
| MPEA—metabolite pathway enrichment analysis M Kankainen, P Gopalacharyulu, L Holm, M Orešič Bioinformatics 27 (13), 1878-1879, 2011 | 108 | 2011 |
| Metabolic regulation in progression to autoimmune diabetes M Sysi-Aho, A Ermolov, PV Gopalacharyulu, A Tripathi, ... PLoS Computational Biology 7 (10), e1002257, 2011 | 101 | 2011 |
| Cord serum lipidome in prediction of islet autoimmunity and type 1 diabetes M Orešič, P Gopalacharyulu, J Mykkänen, N Lietzen, M Mäkinen, ... Diabetes 62 (9), 3268-3274, 2013 | 100 | 2013 |
| Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis SK Sieberts, F Zhu, J García-García, E Stahl, A Pratap, G Pandey, ... Nature communications 7 (1), 12460, 2016 | 92 | 2016 |
| Accumulated metabolites of hydroxybutyric acid serve as diagnostic and prognostic biomarkers of ovarian high-grade serous carcinomas M Hilvo, I De Santiago, P Gopalacharyulu, WD Schmitt, J Budczies, ... Cancer research 76 (4), 796-804, 2016 | 91 | 2016 |
| Insulin signaling regulates fatty acid catabolism at the level of CoA activation X Xu, P Gopalacharyulu, T Seppänen-Laakso, AL Ruskeepää, CC Aye, ... PLoS Genetics 8 (1), e1002478, 2012 | 89 | 2012 |
| Characterization of microbial metabolism of Syrah grape products in an in vitro colon model using targeted and non-targeted analytical approaches AM Aura, I Mattila, T Hyötyläinen, P Gopalacharyulu, V Cheynier, ... European journal of nutrition 52, 833-846, 2013 | 76 | 2013 |
| Dietary carbohydrate modification alters serum metabolic profiles in individuals with the metabolic syndrome M Lankinen, U Schwab, PV Gopalacharyulu, T Seppänen-Laakso, ... Nutrition, Metabolism and Cardiovascular Diseases 20 (4), 249-257, 2010 | 74 | 2010 |
| 1-hour post-OGTT glucose improves the early prediction of type 2 diabetes by clinical and metabolic markers G Peddinti, M Bergman, T Tuomi, L Groop The Journal of Clinical Endocrinology & Metabolism 104 (4), 1131-1140, 2019 | 72 | 2019 |
Matej OrešičProfessor of Medicine (Systems Medicine), Örebro University & University of TurkuVerified email at oru.se
