| Characterization of the R263K mutation in HIV-1 integrase that confers low-level resistance to the second-generation integrase strand transfer inhibitor dolutegravir PK Quashie, T Mesplède, YS Han, M Oliveira, DN Singhroy, T Fujiwara, ... Journal of virology 86 (5), 2696-2705, 2012 | 260 | 2012 |
| A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa E Wilkinson, M Giovanetti, H Tegally, JE San, R Lessells, D Cuadros, ... Science 374 (6566), 423-431, 2021 | 187 | 2021 |
| Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure T Mesplède, PK Quashie, N Osman, Y Han, DN Singhroy, Y Lie, ... Retrovirology 10, 1-7, 2013 | 150 | 2013 |
| Compensation by the E138K mutation in HIV-1 reverse transcriptase for deficits in viral replication capacity and enzyme processivity associated with the M184I/V mutations HT Xu, EL Asahchop, M Oliveira, PK Quashie, Y Quan, BG Brenner, ... Journal of virology 85 (21), 11300-11308, 2011 | 115 | 2011 |
| Evolution of HIV integrase resistance mutations PK Quashie, T Mesplède, MA Wainberg Current opinion in infectious diseases 26 (1), 43-49, 2013 | 112 | 2013 |
| Novel therapeutic strategies targeting HIV integrase PK Quashie, RD Sloan, MA Wainberg BMC medicine 10, 1-11, 2012 | 95 | 2012 |
| The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness M Wares, T Mesplède, PK Quashie, N Osman, Y Han, MA Wainberg Retrovirology 11, 1-8, 2014 | 90 | 2014 |
| The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance H Tegally, JE San, M Cotten, M Moir, B Tegomoh, G Mboowa, DP Martin, ... Science 378 (6615), eabq5358, 2022 | 89 | 2022 |
| Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase PK Quashie, M Oliviera, T Veres, N Osman, YS Han, S Hassounah, Y Lie, ... Journal of virology 89 (6), 3163-3175, 2015 | 82 | 2015 |
| The development of novel HIV integrase inhibitors and the problem of drug resistance MA Wainberg, T Mesplède, PK Quashie Current opinion in virology 2 (5), 656-662, 2012 | 76 | 2012 |
| Resistance to HIV integrase inhibitors T Mesplède, PK Quashie, MA Wainberg Current opinion in HIV and AIDS 7 (5), 401-408, 2012 | 71 | 2012 |
| Biochemical analysis of the role of G118R-linked dolutegravir drug resistance substitutions in HIV-1 integrase PK Quashie, T Mesplède, YS Han, T Veres, N Osman, S Hassounah, ... Antimicrobial agents and chemotherapy 57 (12), 6223-6235, 2013 | 69 | 2013 |
| Resistance mutations against dolutegravir in HIV integrase impair the emergence of resistance against reverse transcriptase inhibitors M Oliveira, T Mesplede, PK Quashie, D Moïsi, MA Wainberg Aids 28 (6), 813-819, 2014 | 68 | 2014 |
| Automethylation of protein arginine methyltransferase 6 (PRMT6) regulates its stability and its anti-HIV-1 activity DN Singhroy, T Mesplède, A Sabbah, PK Quashie, JP Falgueyret, ... Retrovirology 10, 1-10, 2013 | 63 | 2013 |
| Integrase strand transfer inhibitors in the management of HIV-positive individuals T Mesplède, PK Quashie, V Zanichelli, MA Wainberg Annals of medicine 46 (3), 123-129, 2014 | 57 | 2014 |
| HIV drug resistance and the advent of integrase inhibitors PK Quashie, T Mesplède, MA Wainberg Current infectious disease reports 15, 85-100, 2013 | 56 | 2013 |
| Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity T Mesplede, N Osman, M Wares, PK Quashie, S Hassounah, K Anstett, ... Journal of Antimicrobial Chemotherapy 69 (10), 2733-2740, 2014 | 55 | 2014 |
| Evolution of a novel pathway leading to dolutegravir resistance in a patient harbouring N155H and multiclass drug resistance I Hardy, B Brenner, P Quashie, R Thomas, C Petropoulos, W Huang, ... Journal of Antimicrobial Chemotherapy 70 (2), 405-411, 2015 | 50 | 2015 |
| Identification of a pyridoxine-derived small-molecule inhibitor targeting dengue virus RNA-dependent RNA polymerase HT Xu, SP Colby-Germinario, S Hassounah, PK Quashie, Y Han, ... Antimicrobial agents and chemotherapy 60 (1), 600-608, 2016 | 43 | 2016 |
| Recommendations for empowering early career researchers to improve research culture and practice BA Kent, C Holman, E Amoako, A Antonietti, JM Azam, H Ballhausen, ... PLoS Biology 20 (7), e3001680, 2022 | 34 | 2022 |
