The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations S Nag, DV Trivedi, SS Sarkar, AS Adhikari, MS Sunitha, S Sutton, ... Nature structural & molecular biology 24 (6), 525-533, 2017 | 194 | 2017 |
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale X Li, Z Li, H Zhou, SM Gaynor, Y Liu, H Chen, R Sun, R Dey, DK Arnett, ... Nature genetics 52 (9), 969-983, 2020 | 162 | 2020 |
Multidimensional structure-function relationships in human β-cardiac myosin from population-scale genetic variation JR Homburger, EM Green, C Caleshu, MS Sunitha, RE Taylor, ... Proceedings of the National Academy of Sciences 113 (24), 6701-6706, 2016 | 119 | 2016 |
Genome sequencing of herb Tulsi (Ocimum tenuiflorum) unravels key genes behind its strong medicinal properties AK Upadhyay, AR Chacko, A Gandhimathi, P Ghosh, K Harini, AP Joseph, ... BMC plant biology 15, 1-20, 2015 | 111 | 2015 |
Mechanistic heterogeneity in contractile properties of α-tropomyosin (TPM1) mutants associated with inherited cardiomyopathies TM Gupte, F Haque, B Gangadharan, MS Sunitha, S Mukherjee, ... Journal of Biological Chemistry 290 (11), 7003-7015, 2015 | 51 | 2015 |
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies Z Li, X Li, H Zhou, SM Gaynor, MS Selvaraj, T Arapoglou, C Quick, Y Liu, ... Nature methods 19 (12), 1599-1611, 2022 | 44 | 2022 |
Molecular mechanisms and structural features of cardiomyopathy-causing troponin T mutants in the tropomyosin overlap region B Gangadharan, MS Sunitha, S Mukherjee, RR Chowdhury, F Haque, ... Proceedings of the National Academy of Sciences 114 (42), 11115-11120, 2017 | 38 | 2017 |
Whole genome sequence analysis of blood lipid levels in> 66,000 individuals MS Selvaraj, X Li, Z Li, A Pampana, DY Zhang, J Park, S Aslibekyan, ... Nature communications 13 (1), 5995, 2022 | 34 | 2022 |
Multiancestry genome-wide association study of aortic stenosis identifies multiple novel loci in the Million Veteran Program AM Small, GM Peloso, J Linefsky, J Aragam, A Galloway, V Tanukonda, ... Circulation 147 (12), 942-955, 2023 | 29 | 2023 |
Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes G Hindy, P Dornbos, MD Chaffin, DJ Liu, M Wang, MS Selvaraj, D Zhang, ... The American Journal of Human Genetics 109 (1), 81-96, 2022 | 27 | 2022 |
The transcriptome enables the identification of candidate genes behind medicinal value of Drumstick tree (Moringa oleifera) SN Pasha, KM Shafi, AG Joshi, I Meenakshi, K Harini, J Mahita, ... Genomics 112 (1), 621-628, 2020 | 27 | 2020 |
Polygenic prediction of preeclampsia and gestational hypertension MC Honigberg, B Truong, RR Khan, B Xiao, L Bhatta, HMT Vy, ... Nature medicine 29 (6), 1540-1549, 2023 | 23 | 2023 |
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies X Li, C Quick, H Zhou, SM Gaynor, Y Liu, H Chen, MS Selvaraj, R Sun, ... Nature genetics 55 (1), 154-164, 2023 | 21 | 2023 |
Structural attributes for the recognition of weak and anomalous regions in coiled-coils of myosins and other motor proteins MS Sunitha, AG Nair, A Charya, K Jadhav, S Mukhopadhyay, ... BMC research notes 5, 1-16, 2012 | 16 | 2012 |
Myosinome: A database of myosins from select eukaryotic genomes to facilitate analysis of sequence-structure-function relationships DP Syamaladevi, MS Sunitha, S Kalaimathy, CC Reddy, M Iftekhar, ... Bioinformatics and Biology Insights 6, BBI. S9902, 2012 | 10 | 2012 |
Beyond the myosin mesa: A potential unifying hypothesis on the underlying molecular basis of hyper-contractility caused by a majority of hypertrophic cardiomyopathy mutations S Nag, DV Trivedi, SS Sarkar, S Sutton, KM Ruppel, JA Spudich bioRxiv, 065508, 2016 | 7 | 2016 |
Dataset for the combined transcriptome assembly of M. oleifera and functional annotation KM Shafi, AG Joshi, I Meenakshi, SN Pasha, K Harini, J Mahita, ... Data in Brief 30, 105416, 2020 | 5 | 2020 |
Identification and stratification of systemic lupus erythematosus patients into two transcriptionally distinct clusters based on IFN-I signature V Shobha, A Mohan, AV Malini, P Chopra, P Karunanithi, ... Lupus 30 (5), 762-774, 2021 | 4 | 2021 |
Integrative structural modelling of the cardiac thin filament: energetics at the interface and conservation patterns reveal a spotlight on period 2 of tropomyosin SS Margaret, JA Mercer, JA Spudich, R Sowdhamini Bioinformatics and Biology Insights 6, BBI. S9798, 2012 | 4 | 2012 |
Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study Y Wang, MS Selvaraj, X Li, Z Li, JA Holdcraft, DK Arnett, JC Bis, ... The American Journal of Human Genetics 110 (10), 1704-1717, 2023 | 3 | 2023 |