| Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell–derived factor-1 JA Burger, N Tsukada, M Burger, NJ Zvaifler, M Dell'Aquila, TJ Kipps Blood, The Journal of the American Society of Hematology 96 (8), 2655-2663, 2000 | 1001 | 2000 |
| Chronic lymphocytic leukemia B cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells JA Burger, M Burger, TJ Kipps Blood, The Journal of the American Society of Hematology 94 (11), 3658-3667, 1999 | 666 | 1999 |
| Small peptide inhibitors of the CXCR4 chemokine receptor (CD184) antagonize the activation, migration, and antiapoptotic responses of CXCL12 in chronic lymphocytic leukemia B cells M Burger, T Hartmann, M Krome, J Rawluk, H Tamamura, N Fujii, ... Blood 106 (5), 1824-1830, 2005 | 378 | 2005 |
| CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells TN Hartmann, JA Burger, A Glodek, N Fujii, M Burger Oncogene 24 (27), 4462-4471, 2005 | 360 | 2005 |
| IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways IU Schraufstatter, J Chung, M Burger American Journal of Physiology-Lung Cellular and Molecular Physiology 280 (6 …, 2001 | 348 | 2001 |
| Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells M Burger, A Glodek, T Hartmann, A Schmitt-Gräff, LE Silberstein, N Fujii, ... Oncogene 22 (50), 8093-8101, 2003 | 344 | 2003 |
| Spleen tyrosine kinase is overexpressed and represents a potential therapeutic target in chronic lymphocytic leukemia M Buchner, S Fuchs, G Prinz, D Pfeifer, K Bartholomé, M Burger, ... Cancer research 69 (13), 5424-5432, 2009 | 218 | 2009 |
| Spleen tyrosine kinase inhibition prevents chemokine-and integrin-mediated stromal protective effects in chronic lymphocytic leukemia M Buchner, C Baer, G Prinz, C Dierks, M Burger, T Zenz, S Stilgenbauer, ... Blood, The Journal of the American Society of Hematology 115 (22), 4497-4506, 2010 | 214 | 2010 |
| Point mutation causing constitutive signaling of CXCR2 leads to transforming activity similar to Kaposi’s sarcoma herpesvirus-G protein-coupled receptor M Burger, JA Burger, RC Hoch, Z Oades, H Takamori, IU Schraufstatter The Journal of Immunology 163 (4), 2017-2022, 1999 | 191 | 1999 |
| Autocrine growth effect of IL-8 and GROα on a human pancreatic cancer cell line, Capan-1 H Takamori, ZG Oades, RC Hoch, M Burger, IU Schraufstatter Pancreas 21 (1), 52-56, 2000 | 188 | 2000 |
| IL-8-mediated cell migration in endothelial cells depends on cathepsin B activity and transactivation of the epidermal growth factor receptor IU Schraufstatter, K Trieu, M Zhao, DM Rose, RA Terkeltaub, M Burger The Journal of Immunology 171 (12), 6714-6722, 2003 | 115 | 2003 |
| KSHV-GPCR and CXCR2 transforming capacity and angiogenic responses are mediated through a JAK2-STAT3-dependent pathway M Burger, T Hartmann, JA Burger, I Schraufstatter Oncogene 24 (12), 2067-2075, 2005 | 106 | 2005 |
| CXCR4 chemokine receptors (CD184) and α4β1 integrins mediate spontaneous migration of human CD34+ progenitors and acute myeloid leukaemia cells … JA Burger, A Spoo, A Dwenger, M Burger, D Behringer British journal of haematology 122 (4), 579-589, 2003 | 103 | 2003 |
| Circulating B-cell chronic lymphocytic leukemia cells display impaired migration to lymph nodes and bone marrow TN Hartmann, V Grabovsky, W Wang, P Desch, G Rubenzer, S Wollner, ... Cancer research 69 (7), 3121-3130, 2009 | 101 | 2009 |
| CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM‐B M Leick, J Catusse, M Follo, RJ Nibbs, TN Hartmann, H Veelken, ... Immunology 129 (4), 536-546, 2010 | 95 | 2010 |
| The therapeutic potential of CXCR4 antagonists in the treatment of HIV infection, cancer metastasis and rheumatoid arthritis H Tamamura, N Fujii Expert opinion on therapeutic targets 9 (6), 1267-1282, 2005 | 89 | 2005 |
| Sphingosine-1-phosphate receptors control B-cell migration through signaling components associated with primary immunodeficiencies, chronic lymphocytic leukemia, and multiple … H Sic, H Kraus, J Madl, KA Flittner, AL von Münchow, K Pieper, M Rizzi, ... Journal of Allergy and Clinical Immunology 134 (2), 420-428. e15, 2014 | 86 | 2014 |
| PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1) S Decker, J Finter, AJ Forde, S Kissel, J Schwaller, TS Mack, A Kuhn, ... Molecular cancer therapeutics 13 (5), 1231-1245, 2014 | 84 | 2014 |
| Tumor cell heterogeneity in Small Cell Lung Cancer (SCLC): phenotypical and functional differences associated with Epithelial-Mesenchymal Transition (EMT) and DNA methylation … A Krohn, T Ahrens, A Yalcin, T Plönes, J Wehrle, S Taromi, S Wollner, ... PloS one 9 (6), e100249, 2014 | 76 | 2014 |
| Insulin-like growth factor-1 receptor (IGF1R) as a novel target in chronic lymphocytic leukemia N Yaktapour, R Übelhart, J Schüler, K Aumann, C Dierks, M Burger, ... Blood, The Journal of the American Society of Hematology 122 (9), 1621-1633, 2013 | 76 | 2013 |
