Junichi Iwata
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Loss of autophagy in the central nervous system causes neurodegeneration in mice
M Komatsu, S Waguri, T Chiba, S Murata, J Iwata, I Tanida, T Ueno, ...
Nature 441 (7095), 880-884, 2006
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
M Komatsu, S Waguri, T Ueno, J Iwata, S Murata, I Tanida, J Ezaki, ...
Journal of Cell Biology 169 (3), 425-434, 2005
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
M Komatsu, S Waguri, M Koike, Y Sou, T Ueno, T Hara, N Mizushima, ...
Cell 131 (6), 1149-1163, 2007
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
M Komatsu, QJ Wang, GR Holstein, VL Friedrich, J Iwata, E Kominami, ...
Proceedings of the National Academy of Sciences 104 (36), 14489-14494, 2007
The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice
Y Sou, S Waguri, J Iwata, T Ueno, T Fujimura, T Hara, N Sawada, ...
Molecular biology of the cell 19 (11), 4762-4775, 2008
Excess peroxisomes are degraded by autophagic machinery in mammals
J Iwata, J Ezaki, M Komatsu, S Yokota, T Ueno, I Tanida, T Chiba, ...
Journal of Biological Chemistry 281 (7), 4035-4041, 2006
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels
J Ezaki, N Matsumoto, M Takeda-Ezaki, M Komatsu, K Takahashi, ...
Autophagy 7 (7), 727-736, 2011
Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice
J Iwata, JG Hacia, A Suzuki, PA Sanchez-Lara, M Urata, Y Chai
The Journal of clinical investigation 122 (3), 873-885, 2012
The mechanism of TGF‐β signaling during palate development
J Iwata, C Parada, Y Chai
Oral diseases 17 (8), 733-744, 2011
Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface
T Kawakubo, K Okamoto, J Iwata, M Shin, Y Okamoto, A Yasukochi, ...
Cancer research 67 (22), 10869-10878, 2007
The FaceBase Consortium: a comprehensive program to facilitate craniofacial research
H Hochheiser, BJ Aronow, K Artinger, TH Beaty, JF Brinkley, Y Chai, ...
Developmental biology 355 (2), 175-182, 2011
Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice
J Iwata, A Suzuki, RC Pelikan, TV Ho, PA Sanchez-Lara, M Urata, ...
Development 140 (6), 1220-1230, 2013
TGF-β mediated FGF10 signaling in cranial neural crest cells controls development of myogenic progenitor cells through tissue–tissue interactions during tongue morphogenesis
R Hosokawa, K Oka, T Yamaza, J Iwata, M Urata, X Xu, P Bringas Jr, ...
Developmental biology 341 (1), 186-195, 2010
Transforming growth factor-β regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derivedá…
J Iwata, R Hosokawa, PA Sanchez-Lara, M Urata, H Slavkin, Y Chai
Journal of Biological Chemistry 285 (7), 4975-4982, 2010
WNT/β-catenin signaling regulates multiple steps of myogenesis by regulating step-specific targets
A Suzuki, RC Pelikan, J Iwata
Molecular and cellular biology 35 (10), 1763-1776, 2015
Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatalá…
J Iwata, L Tung, M Urata, JG Hacia, R Pelikan, A Suzuki, L Ramenzoni, ...
Journal of Biological Chemistry 287 (4), 2353-2363, 2012
CTGF mediates Smad-dependent transforming growth factor β signaling to regulate mesenchymal cell proliferation during palate development
C Parada, J Li, J Iwata, A Suzuki, Y Chai
Molecular and cellular biology 33 (17), 3482-3493, 2013
Mice with Tak1 deficiency in neural crest lineage exhibit cleft palate associated with abnormal tongue development
Z Song, C Liu, J Iwata, S Gu, A Suzuki, C Sun, W He, R Shu, L Li, Y Chai, ...
Journal of Biological Chemistry 288 (15), 10440-10450, 2013
Molecular mechanisms of midfacial developmental defects
A Suzuki, DR Sangani, A Ansari, J Iwata
Developmental Dynamics 245 (3), 276-293, 2016
Msx1 and Dlx5 function synergistically to regulate frontal bone development
IH Chung, J Han, J Iwata, Y Chai
genesis 48 (11), 645-655, 2010
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