APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease KL Youmans, LM Tai, E Nwabuisi-Heath, L Jungbauer, T Kanekiyo, ... Journal of Biological Chemistry 287 (50), 41774-41786, 2012 | 280 | 2012 |
APOE genotype alters glial activation and loss of synaptic markers in mice Y Zhu, E Nwabuisi‐Heath, SB Dumanis, LM Tai, C Yu, GW Rebeck, ... Glia 60 (4), 559-569, 2012 | 229 | 2012 |
Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition GA Rodriguez, LM Tai, MJ LaDu, GW Rebeck Journal of neuroinflammation 11, 1-14, 2014 | 191 | 2014 |
The role of APOE in cerebrovascular dysfunction LM Tai, R Thomas, FM Marottoli, KP Koster, T Kanekiyo, AWJ Morris, G Bu Acta neuropathologica 131, 709-723, 2016 | 184 | 2016 |
Levels of Soluble Apolipoprotein E/Amyloid-β (Aβ) Complex Are Reduced and Oligomeric Aβ Increased with APOE4 and Alzheimer Disease in a Transgenic Mouse Model and Human Samples … LM Tai, T Bilousova, L Jungbauer, SK Roeske, KL Youmans, C Yu, ... Journal of Biological Chemistry 288 (8), 5914-5926, 2013 | 181 | 2013 |
Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody KL Youmans, LM Tai, T Kanekiyo, WB Stine Jr, SC Michon, ... Molecular neurodegeneration 7, 1-14, 2012 | 174 | 2012 |
APOE‐modulated Aβ‐induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective LM Tai, S Ghura, KP Koster, V Liakaite, M Maienschein‐Cline, P Kanabar, ... Journal of neurochemistry 133 (4), 465-488, 2015 | 167 | 2015 |
Dietary docosahexaenoic acid (DHA) as lysophosphatidylcholine, but not as free acid, enriches brain DHA and improves memory in adult mice D Sugasini, R Thomas, PCR Yalagala, LM Tai, PV Subbaiah Scientific Reports 7 (1), 11263, 2017 | 166 | 2017 |
Amyloid‐β‐induced occludin down‐regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation LM Tai, KA Holloway, DK Male, AJ Loughlin, IA Romero Journal of cellular and molecular medicine 14 (5), 1101-1112, 2010 | 149 | 2010 |
P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-β LM Tai, AJ Loughlin, DK Male, IA Romero Journal of Cerebral Blood Flow & Metabolism 29 (6), 1079-1083, 2009 | 140 | 2009 |
Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk LM Tai, S Mehra, V Shete, S Estus, GW Rebeck, G Bu, MJ LaDu Molecular neurodegeneration 9, 1-14, 2014 | 135 | 2014 |
APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice D Liu, X Pan, J Zhang, H Shen, NC Collins, AM Cole, KP Koster, ... Molecular neurodegeneration 10, 1-17, 2015 | 99 | 2015 |
Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo LM Tai, KP Koster, J Luo, SH Lee, Y Wang, NC Collins, MB Aissa, ... Journal of Biological Chemistry 289 (44), 30538-30555, 2014 | 98 | 2014 |
Enrichment of brain docosahexaenoic acid (DHA) is highly dependent upon the molecular carrier of dietary DHA: Lysophosphatidylcholine is more efficient than either … D Sugasini, PCR Yalagala, A Goggin, LM Tai, PV Subbaiah The Journal of nutritional biochemistry 74, 108231, 2019 | 78 | 2019 |
EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimerʼns disease [S] LM Tai, D Balu, E Avila-Munoz, L Abdullah, R Thomas, N Collins, ... Journal of lipid research 58 (9), 1733-1755, 2017 | 75 | 2017 |
Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123 LM Tai, PS Reddy, MA Lopez-Ramirez, HA Davies, ADK Male, ... Brain research 1292, 14-24, 2009 | 72 | 2009 |
Peripheral Inflammation, Apolipoprotein E4, and Amyloid-β Interact to Induce Cognitive and Cerebrovascular Dysfunction FM Marottoli, Y Katsumata, KP Koster, R Thomas, DW Fardo, LM Tai ASN neuro 9 (4), 1759091417719201, 2017 | 68 | 2017 |
Introducing human APOE into Aβ transgenic mouse models LM Tai, KL Youmans, L Jungbauer, C Yu, MJ LaDu International journal of Alzheimer’s disease 2011, 2011 | 62 | 2011 |
N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability K Kruse, QS Lee, Y Sun, J Klomp, X Yang, F Huang, MY Sun, S Zhao, ... Journal of Cell Biology 218 (1), 299-316, 2019 | 61 | 2019 |
Epidermal growth factor prevents APOE4 and amyloid-beta-induced cognitive and cerebrovascular deficits in female mice R Thomas, P Zuchowska, AWJ Morris, FM Marottoli, S Sunny, R Deaton, ... Acta neuropathologica communications 4, 1-14, 2016 | 50 | 2016 |