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Leon M Tai
Leon M Tai
Assistant Professor of Anatomy and Cell Biology, University of Illinois at Chicago
Verified email at uic.edu
Title
Cited by
Cited by
Year
APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease
KL Youmans, LM Tai, E Nwabuisi-Heath, L Jungbauer, T Kanekiyo, ...
Journal of Biological Chemistry 287 (50), 41774-41786, 2012
2802012
APOE genotype alters glial activation and loss of synaptic markers in mice
Y Zhu, E Nwabuisi‐Heath, SB Dumanis, LM Tai, C Yu, GW Rebeck, ...
Glia 60 (4), 559-569, 2012
2292012
Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition
GA Rodriguez, LM Tai, MJ LaDu, GW Rebeck
Journal of neuroinflammation 11, 1-14, 2014
1912014
The role of APOE in cerebrovascular dysfunction
LM Tai, R Thomas, FM Marottoli, KP Koster, T Kanekiyo, AWJ Morris, G Bu
Acta neuropathologica 131, 709-723, 2016
1842016
Levels of Soluble Apolipoprotein E/Amyloid-β (Aβ) Complex Are Reduced and Oligomeric Aβ Increased with APOE4 and Alzheimer Disease in a Transgenic Mouse Model and Human Samples …
LM Tai, T Bilousova, L Jungbauer, SK Roeske, KL Youmans, C Yu, ...
Journal of Biological Chemistry 288 (8), 5914-5926, 2013
1812013
Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody
KL Youmans, LM Tai, T Kanekiyo, WB Stine Jr, SC Michon, ...
Molecular neurodegeneration 7, 1-14, 2012
1742012
APOE‐modulated Aβ‐induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective
LM Tai, S Ghura, KP Koster, V Liakaite, M Maienschein‐Cline, P Kanabar, ...
Journal of neurochemistry 133 (4), 465-488, 2015
1672015
Dietary docosahexaenoic acid (DHA) as lysophosphatidylcholine, but not as free acid, enriches brain DHA and improves memory in adult mice
D Sugasini, R Thomas, PCR Yalagala, LM Tai, PV Subbaiah
Scientific Reports 7 (1), 11263, 2017
1662017
Amyloid‐β‐induced occludin down‐regulation and increased permeability in human brain endothelial cells is mediated by MAPK activation
LM Tai, KA Holloway, DK Male, AJ Loughlin, IA Romero
Journal of cellular and molecular medicine 14 (5), 1101-1112, 2010
1492010
P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-β
LM Tai, AJ Loughlin, DK Male, IA Romero
Journal of Cerebral Blood Flow & Metabolism 29 (6), 1079-1083, 2009
1402009
Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk
LM Tai, S Mehra, V Shete, S Estus, GW Rebeck, G Bu, MJ LaDu
Molecular neurodegeneration 9, 1-14, 2014
1352014
APOE4 enhances age-dependent decline in cognitive function by down-regulating an NMDA receptor pathway in EFAD-Tg mice
D Liu, X Pan, J Zhang, H Shen, NC Collins, AM Cole, KP Koster, ...
Molecular neurodegeneration 10, 1-17, 2015
992015
Amyloid-β pathology and APOE genotype modulate retinoid X receptor agonist activity in vivo
LM Tai, KP Koster, J Luo, SH Lee, Y Wang, NC Collins, MB Aissa, ...
Journal of Biological Chemistry 289 (44), 30538-30555, 2014
982014
Enrichment of brain docosahexaenoic acid (DHA) is highly dependent upon the molecular carrier of dietary DHA: Lysophosphatidylcholine is more efficient than either …
D Sugasini, PCR Yalagala, A Goggin, LM Tai, PV Subbaiah
The Journal of nutritional biochemistry 74, 108231, 2019
782019
EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimerʼns disease [S]
LM Tai, D Balu, E Avila-Munoz, L Abdullah, R Thomas, N Collins, ...
Journal of lipid research 58 (9), 1733-1755, 2017
752017
Polarized P-glycoprotein expression by the immortalised human brain endothelial cell line, hCMEC/D3, restricts apical-to-basolateral permeability to rhodamine 123
LM Tai, PS Reddy, MA Lopez-Ramirez, HA Davies, ADK Male, ...
Brain research 1292, 14-24, 2009
722009
Peripheral Inflammation, Apolipoprotein E4, and Amyloid-β Interact to Induce Cognitive and Cerebrovascular Dysfunction
FM Marottoli, Y Katsumata, KP Koster, R Thomas, DW Fardo, LM Tai
ASN neuro 9 (4), 1759091417719201, 2017
682017
Introducing human APOE into Aβ transgenic mouse models
LM Tai, KL Youmans, L Jungbauer, C Yu, MJ LaDu
International journal of Alzheimer’s disease 2011, 2011
622011
N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability
K Kruse, QS Lee, Y Sun, J Klomp, X Yang, F Huang, MY Sun, S Zhao, ...
Journal of Cell Biology 218 (1), 299-316, 2019
612019
Epidermal growth factor prevents APOE4 and amyloid-beta-induced cognitive and cerebrovascular deficits in female mice
R Thomas, P Zuchowska, AWJ Morris, FM Marottoli, S Sunny, R Deaton, ...
Acta neuropathologica communications 4, 1-14, 2016
502016
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