HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth KL Covello, J Kehler, H Yu, JD Gordan, AM Arsham, CJ Hu, PA Labosky, ... Genes & development 20 (5), 557-570, 2006 | 1034 | 2006 |
A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets AM Arsham, JJ Howell, MC Simon Journal of Biological Chemistry 278 (32), 29655-29660, 2003 | 586 | 2003 |
Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1α nor sufficient for HIF-1-dependent target gene transcription AM Arsham, DR Plas, CB Thompson, MC Simon Journal of Biological Chemistry 277 (17), 15162-15170, 2002 | 227 | 2002 |
Nutrient-dependent regulation of autophagy through the target of rapamycin pathway YY Chang, G Juhász, P Goraksha-Hicks, AM Arsham, DR Mallin, ... Biochemical Society Transactions 37 (1), 232-236, 2009 | 208 | 2009 |
Loss of pVHL is sufficient to cause HIF dysregulation in primary cells but does not promote tumor growth FA Mack, WK Rathmell, AM Arsham, J Gnarra, B Keith, MC Simon Cancer cell 3 (1), 75-88, 2003 | 172 | 2003 |
Thinking globally and acting locally with TOR AM Arsham, TP Neufeld Current opinion in cell biology 18 (6), 589-597, 2006 | 167 | 2006 |
Mxi1 is induced by hypoxia in a HIF-1-dependent manner and protects cells from c-Myc-induced apoptosis. PG Corn, MS Ricci, KA Scata, AM Arsham, MC Simon, DT Dicker, ... Cancer biology & therapy 4 (11), 1285, 2005 | 135 | 2005 |
Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis AM Arsham, DR Plas, CB Thompson, MC Simon Cancer research 64 (10), 3500-3507, 2004 | 119 | 2004 |
The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia E Maltepe, B Keith, AM Arsham, JR Brorson, MC Simon Biochemical and biophysical research communications 273 (1), 231-238, 2000 | 111 | 2000 |
A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway AM Arsham, TP Neufeld PloS one 4 (6), e6068, 2009 | 76 | 2009 |
Mechanisms of TSC-mediated control of synapse assembly and axon guidance S Knox, H Ge, BD Dimitroff, Y Ren, KA Howe, AM Arsham, MC Easterday, ... PloS one 2 (4), e375, 2007 | 65 | 2007 |
PI3-K/Akt signaling is neither required for hypoxic stabilization of HIF-1 nor sufficient for HIF-1-dependent target gene transcription AM Arsham, DR Plas, CB Thompson, MC Simon J Biol Chem 277, 15162-15170, 2002 | 9 | 2002 |
tRNA trafficking along the TOR pathway TP Neufeld, AM Arsham Cell Cycle 9 (16), 3146-3150, 2010 | 4 | 2010 |
Tumor suppression through angiogenesis inhibition AM Arsham, MC Simon Tumor Suppressor Genes: Volume 2 Regulation, Function, and Medicinal …, 2003 | 1 | 2003 |
Control of autophagy by target of rapamycin signaling RC Scott, YY Chang, AM Arsham, G Juhasz, TP Neufeld AUTOPHAGY 2 (4), 341-341, 2006 | | 2006 |
Oxygen, hypoxia-inducible factors, and phosphatidylinositol 3-kinase/Akt signaling in tumor growth and gene expression. AM Arsham | | 2004 |