Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment S Müller, G Kohanbash, SJ Liu, B Alvarado, D Carrera, A Bhaduri, ... Genome biology 18, 1-14, 2017 | 548 | 2017 |
Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas G Kohanbash, DA Carrera, S Shrivastav, BJ Ahn, N Jahan, T Mazor, ... The Journal of clinical investigation 127 (4), 1425-1437, 2017 | 364 | 2017 |
Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice PB Watchmaker, K Lahl, M Lee, D Baumjohann, J Morton, SJ Kim, R Zeng, ... Nature immunology 15 (1), 98-108, 2014 | 292 | 2014 |
SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma JH Choe, PB Watchmaker, MS Simic, RD Gilbert, AW Li, NA Krasnow, ... Science translational medicine 13 (591), eabe7378, 2021 | 270 | 2021 |
Novel and shared neoantigen derived from histone 3 variant H3. 3K27M mutation for glioma T cell therapy ZS Chheda, G Kohanbash, K Okada, N Jahan, J Sidney, M Pecoraro, ... Journal of Experimental Medicine 215 (1), 141-157, 2018 | 210 | 2018 |
Mass cytometry detects H3. 3K27M-specific vaccine responses in diffuse midline glioma S Mueller, JM Taitt, JE Villanueva-Meyer, ER Bonner, T Nejo, RR Lulla, ... The Journal of clinical investigation 130 (12), 2022 | 91 | 2022 |
Type-1 polarized dendritic cells primed for high IL-12 production show enhanced activity as cancer vaccines AS Giermasz, JA Urban, Y Nakamura, P Watchmaker, RL Cumberland, ... Cancer immunology, immunotherapy 58, 1329-1336, 2009 | 88 | 2009 |
Independent regulation of chemokine responsiveness and cytolytic function versus CD8+ T cell expansion by dendritic cells PB Watchmaker, E Berk, R Muthuswamy, RB Mailliard, JA Urban, ... The journal of immunology 184 (2), 591-597, 2010 | 85 | 2010 |
Helper roles of NK and CD8+ T cells in the induction of tumor immunity: Polarized dendritic cells as cancer vaccines P Kalinski, Y Nakamura, P Watchmaker, A Giermasz, R Muthuswamy, ... Immunologic research 36, 137-146, 2006 | 75 | 2006 |
Unique challenges for glioblastoma immunotherapy—discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno … P Chuntova, F Chow, PB Watchmaker, M Galvez, AB Heimberger, ... Neuro-oncology 23 (3), 356-375, 2021 | 64 | 2021 |
Memory CD8+ T cells protect dendritic cells from CTL killing PB Watchmaker, JA Urban, E Berk, Y Nakamura, RB Mailliard, ... The Journal of Immunology 180 (6), 3857-3865, 2008 | 60 | 2008 |
Helper function of memory CD8+ T cells: heterologous CD8+ T cells support the induction of therapeutic cancer immunity Y Nakamura, P Watchmaker, J Urban, B Sheridan, A Giermasz, ... Cancer research 67 (20), 10012-10018, 2007 | 44 | 2007 |
Randomized trial of neoadjuvant vaccination with tumor-cell lysate induces T cell response in low-grade gliomas H Ogino, JW Taylor, T Nejo, D Gibson, PB Watchmaker, K Okada, A Saijo, ... The Journal of clinical investigation 132 (3), 2022 | 37 | 2022 |
Transcriptional and functional profiling of human intestinal dendritic cells reveals conserved specialization and a role for Bcl-6 and Blimp-1 in terminal subset differentiation PB Watchmaker, K Lahl, M Lee, D Baumjohann, J Morton, SJ Kim, R Zeng, ... Nature immunology 15 (1), 98, 2014 | 11 | 2014 |
Antigen-dependent inducible T-cell reporter system for PET imaging of breast cancer and glioblastoma J Shin, MFL Parker, I Zhu, A Alanizi, CI Rodriguez, R Liu, PB Watchmaker, ... Journal of Nuclear Medicine 64 (1), 137-144, 2023 | 7 | 2023 |
Multi-antigen recognition circuits overcome challenges of specificity, heterogeneity, and durability in T cell therapy for glioblastoma JH Choe, PB Watchmaker, MS Simic, RD Gilbert, AW Li, NA Krasnow, ... bioRxiv, 2021.01. 07.425632, 2021 | 4 | 2021 |
Tumor-wide RNA splicing aberrations generate immunogenic public neoantigens DW Kwok, NO Stevers, T Nejo, LH Chen, I Etxeberria, J Jung, K Okada, ... bioRxiv, 2023.10. 19.563178, 2023 | 3 | 2023 |
Glioma-neuronal circuit remodeling induces regional immunosuppression T Nejo, S Krishna, C Jimenez, A Yamamichi, JS Young, ... bioRxiv, 2023.08. 04.548295, 2023 | 3 | 2023 |
Glioma-induced neuronal remodeling promotes regional immunosuppression T Nejo, S Krishna, C Jimenez, A Yamamichi, JS Young, T Chen, ... Cancer Research 83 (7_Supplement), 2497-2497, 2023 | 1 | 2023 |
Future development of chimeric antigen receptor T cell therapies for patients suffering from malignant glioma PB Watchmaker, M Colton, PL Pineo-Cavanaugh, H Okada Current opinion in oncology 34 (6), 661-669, 2022 | 1 | 2022 |