IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection N Kerur, MV Veettil, N Sharma-Walia, V Bottero, S Sadagopan, P Otageri, ... Cell host & microbe 9 (5), 363-375, 2011 | 781 | 2011 |
Therapeutic gene causing lymphoma NB Woods, V Bottero, M Schmidt, C Von Kalle, IM Verma Nature 440 (7088), 1123-1123, 2006 | 371 | 2006 |
Activation of transcription factor NF-κB requires ELKS, an IκB kinase regulatory subunit JLD Sigala, V Bottero, DB Young, A Shevchenko, F Mercurio, IM Verma Science 304 (5679), 1963-1967, 2004 | 301 | 2004 |
NF-κB modulation and ionizing radiation: mechanisms and future directions for cancer treatment N Magné, RA Toillon, V Bottero, C Didelot, P Van Houtte, JP Gérard, ... Cancer letters 231 (2), 158-168, 2006 | 237 | 2006 |
IκB kinase-independent IκBα degradation pathway: functional NF-κB activity and implications for cancer therapy V Tergaonkar, V Bottero, M Ikawa, Q Li, IM Verma Molecular and cellular biology 23 (22), 8070-8083, 2003 | 201 | 2003 |
Phosphorylation of p53 by IκB kinase 2 promotes its degradation by β-TrCP Y Xia, RC Padre, TH De Mendoza, V Bottero, VB Tergaonkar, IM Verma Proceedings of the National Academy of Sciences 106 (8), 2629-2634, 2009 | 188 | 2009 |
IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications KE Johnson, V Bottero, S Flaherty, S Dutta, VV Singh, B Chandran PLoS pathogens 10 (11), e1004503, 2014 | 170 | 2014 |
Kaposi's sarcoma-associated herpesvirus latency in endothelial and B cells activates gamma interferon-inducible protein 16-mediated inflammasomes VV Singh, N Kerur, V Bottero, S Dutta, S Chakraborty, MA Ansari, ... Journal of virology 87 (8), 4417-4431, 2013 | 167 | 2013 |
Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells V Bottero, V Busuttil, A Loubat, N Magné, JL Fischel, G Milano, JF Peyron Cancer research 61 (21), 7785-7791, 2001 | 165 | 2001 |
Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-κB activation and cell survival S Ghosh, V Tergaonkar, CV Rothlin, RG Correa, V Bottero, P Bist, ... Cancer cell 10 (3), 215-226, 2006 | 163 | 2006 |
Enhanced NF-κB activation and cellular function in macrophages lacking IκB kinase 1 (IKK1) Q Li, Q Lu, V Bottero, G Estepa, L Morrison, F Mercurio, IM Verma Proceedings of the National Academy of Sciences 102 (35), 12425-12430, 2005 | 163 | 2005 |
Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion N Sharma-Walia, AG Paul, V Bottero, S Sadagopan, MV Veettil, N Kerur, ... PLoS pathogens 6 (2), e1000777, 2010 | 140 | 2010 |
NF-κB and the regulation of hematopoiesis V Bottero, S Withoff, IM Verma Cell Death & Differentiation 13 (5), 785-797, 2006 | 139 | 2006 |
Kaposi's sarcoma-associated herpesvirus induces sustained NF-κB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential … S Sadagopan, N Sharma-Walia, MV Veettil, H Raghu, R Sivakumar, ... Journal of virology 81 (8), 3949-3968, 2007 | 135 | 2007 |
Kaposi’s sarcoma-associated herpesvirus interacts with EphrinA2 receptor to amplify signaling essential for productive infection S Chakraborty, MV Veettil, V Bottero, B Chandran Proceedings of the National Academy of Sciences 109 (19), E1163-E1172, 2012 | 122 | 2012 |
IκB-α, the NF-κB inhibitory subunit, interacts with ANT, the mitochondrial ATP/ADP translocator V Bottero, F Rossi, M Samson, M Mari, P Hofman, JF Peyron Journal of Biological Chemistry 276 (24), 21317-21324, 2001 | 111 | 2001 |
Monitoring NF-κB transactivation potential via real-time PCR quantification of IκB-α gene expression V Bottero, V Imbert, C Freiin, JL Formento, JF Peyron Molecular Diagnosis 7, 187-194, 2003 | 99 | 2003 |
Lipid rafts of primary endothelial cells are essential for Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8-induced phosphatidylinositol 3-kinase and RhoA-GTPases … H Raghu, N Sharma-Walia, MV Veettil, S Sadagopan, A Caballero, ... Journal of virology 81 (15), 7941-7959, 2007 | 98 | 2007 |
Kaposi's Sarcoma-Associated Herpesvirus Induces Nrf2 during De Novo Infection of Endothelial Cells to Create a Microenvironment Conducive to Infection O Gjyshi, V Bottero, MV Veettil, S Dutta, VV Singh, L Chikoti, B Chandran PLoS pathogens 10 (10), e1004460, 2014 | 91 | 2014 |
Biological and clinical implications of comorbidities in Parkinson’s disease JA Santiago, V Bottero, JA Potashkin Frontiers in aging neuroscience 9, 394, 2017 | 88 | 2017 |