Amal Kamal Abdel-Aziz
Amal Kamal Abdel-Aziz
Other namesAmal Kamal Saadeldin
Associate Professor of Pharmacology & Toxicology, ASU and Postdoctoral Pharmacologist, IEO, Italy
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Discovery of potent VEGFR-2 inhibitors based on furopyrimidine and thienopyrimidne scaffolds as cancer targeting agents
MA Aziz, RAT Serya, DS Lasheen, AK Abdel-Aziz, A Esmat, AM Mansour, ...
Scientific reports 6 (1), 24460, 2016
Astaxanthin ameliorates doxorubicin-induced cognitive impairment (chemobrain) in experimental rat model: impact on oxidative, inflammatory, and apoptotic machineries
SE El-Agamy, AK Abdel-Aziz, S Wahdan, A Esmat, SS Azab
Molecular neurobiology 55, 5727-5740, 2018
Chloroquine synergizes sunitinib cytotoxicity via modulating autophagic, apoptotic and angiogenic machineries
AK Abdel-Aziz, S Shouman, E El-Demerdash, M Elgendy, AB Abdel-Naim
Chemico-biological interactions 217, 28-40, 2014
Chemotherapy and cognition: comprehensive review on doxorubicin-induced chemobrain
SE El-Agamy, AK Abdel-Aziz, A Esmat, SS Azab
Cancer chemotherapy and pharmacology 84, 1-14, 2019
Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner
M Elgendy, M Ciro, AK Abdel-Aziz, G Belmonte, RD Zuffo, C Mercurio, ...
Nature communications 5 (1), 5637, 2014
Dual modulation of MCL-1 and mTOR determines the response to sunitinib
M Elgendy, AK Abdel-Aziz, SL Renne, V Bornaghi, G Procopio, ...
The Journal of clinical investigation 127 (1), 153-168, 2017
Surmounting the resistance against EGFR inhibitors through the development of thieno [2, 3-d] pyrimidine-based dual EGFR/HER2 inhibitors
SN Milik, AK Abdel-Aziz, DS Lasheen, RAT Serya, S Minucci, ...
European Journal of Medicinal Chemistry 155, 316-336, 2018
Mechanistic approach of the inhibitory effect of chrysin on inflammatory and apoptotic events implicated in radiation-induced premature ovarian failure: emphasis on TGF-β/MAPKs …
EM Mantawy, RS Said, AK Abdel-Aziz
Biomedicine & Pharmacotherapy 109, 293-303, 2019
The tyrosine kinase inhibitor, sunitinib malate, induces cognitive impairment in vivo via dysregulating VEGFR signaling, apoptotic and autophagic machineries
AK Abdel-Aziz, EM Mantawy, RS Said, R Helwa
Experimental neurology 283, 129-141, 2016
Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis
MK Saadeldin, AK Abdel-Aziz, A Abdellatif
Medical hypotheses 146, 110365, 2021
Serum sclerostin and irisin as predictive markers for atherosclerosis in Egyptian type II diabetic female patients: A case control study
MK Saadeldin, SS Elshaer, IA Emara, M Maged, AK Abdel-Aziz
PLoS One 13 (11), e0206761, 2018
Rational design, synthesis and molecular modeling studies of novel anti-oncological alkaloids against melanoma
AS Girgis, SS Panda, AM Srour, H Farag, NSM Ismail, M Elgendy, ...
Organic & Biomolecular Chemistry 13 (23), 6619-6633, 2015
Modulation of imatinib cytotoxicity by selenite in HCT 116 colorectal cancer cells
AK Abdel‐Aziz, SSE Azab, SS Youssef, AM El‐Sayed, E El‐Demerdash, ...
Basic & clinical pharmacology & toxicology 116 (1), 37-46, 2015
Tuning mTORC1 activity dictates the response of acute myeloid leukemia to LSD1 inhibition
AK Abdel-Aziz, I Pallavicini, E Ceccacci, G Meroni, MK Saadeldin, ...
haematologica 105 (8), 2105, 2020
From resistance to sensitivity: insights and implications of biphasic modulation of autophagy by sunitinib
AK Abdel-Aziz, AB Abdel-Naim, S Shouman, S Minucci, M Elgendy
Frontiers in Pharmacology 8, 718, 2017
Comparative study of anti-VEGF Ranibizumab and Interleukin-6 receptor antagonist Tocilizumab in Adjuvant-induced Arthritis
AES Abdel-Maged, AM Gad, AK Abdel-Aziz, MM Aboulwafa, SS Azab
Toxicology and Applied Pharmacology 356, 65-75, 2018
Chloroquine as a promising adjuvant chemotherapy together with sunitinib
AK Abdel-Aziz, S Shouman, E El-Demerdash, M Elgendy, AB Abdel-Naim
strategies 12, 15, 2014
Discovery of a benzimidazole-based dual FLT3/TrKA inhibitor targeting acute myeloid leukemia
EME Dokla, AK Abdel-Aziz, SN Milik, MJ McPhillie, S Minucci, ...
Bioorganic & Medicinal Chemistry 56, 116596, 2022
Novel molecular mechanisms underlying the ameliorative effect of N-acetyl-L-cysteine against ϒ-radiation-induced premature ovarian failure in rats
EM Mantawy, RS Said, DH Kassem, AK Abdel-Aziz, AM Badr
Ecotoxicology and Environmental Safety 206, 111190, 2020
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