| Primary structures of PYY, [Pro34]PYY, and PYY-(3–36) confer different conformations and receptor selectivity DA Keire, P Mannon, M Kobayashi, JH Walsh, TE Solomon, JR Reeve Jr American Journal of Physiology-Gastrointestinal and Liver Physiology 279 (1 …, 2000 | 181 | 2000 |
| Kinetics and equilibria of thiol/disulfide interchange reactions of selected biological thiols and related molecules with oxidized glutathione DA Keire, E Strauss, W Guo, B Noszal, DL Rabenstein The Journal of Organic Chemistry 57 (1), 123-127, 1992 | 164 | 1992 |
| Daily, intermittent intravenous infusion of peptide YY (3-36) reduces daily food intake and adiposity in rats PK Chelikani, AC Haver, JR Reeve Jr, DA Keire, RD Reidelberger American Journal of Physiology-Regulatory, Integrative and Comparative …, 2006 | 134 | 2006 |
| Structure and receptor binding of PYY analogs DA Keire, CW Bowers, TE Solomon, JR Reeve Jr Peptides 23 (2), 305-321, 2002 | 133 | 2002 |
| The US regulatory and pharmacopeia response to the global heparin contamination crisis AY Szajek, E Chess, K Johansen, G Gratzl, E Gray, D Keire, RJ Linhardt, ... Nature biotechnology 34 (6), 625-630, 2016 | 116 | 2016 |
| CCK-58 is the only detectable endocrine form of cholecystokinin in rat JR Reeve Jr, GM Green, P Chew, VE Eysselein, DA Keire American Journal of Physiology-Gastrointestinal and Liver Physiology 285 (2 …, 2003 | 111 | 2003 |
| A retrospective evaluation of the use of mass spectrometry in FDA biologics license applications S Rogstad, A Faustino, A Ruth, D Keire, M Boyne, J Park Journal of the American Society for Mass Spectrometry 28 (5), 786-794, 2016 | 110 | 2016 |
| Mechanism and energetics for complexation of 90Y with 1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid (DOTA), a model for cancer radioimmunotherapy YH Jang, M Blanco, S Dasgupta, DA Keire, JE Shively, WA Goddard Journal of the American Chemical Society 121 (26), 6142-6151, 1999 | 105 | 1999 |
| The RAPID method for blood processing yields new insight in plasma concentrations and molecular forms of circulating gut peptides A Stengel, D Keire, M Goebel, L Evilevitch, B Wiggins, Y Tache, ... Endocrinology 150 (11), 5113-5118, 2009 | 96 | 2009 |
| Solution Structure of Monomeric Peptide YY Supports the Functional Significance of the PP-Fold, DA Keire, M Kobayashi, TE Solomon, JR Reeve Biochemistry 39 (32), 9935-9942, 2000 | 92 | 2000 |
| Analysis of crude heparin by 1H NMR, capillary electrophoresis, and strong-anion-exchange-HPLC for contamination by over sulfated chondroitin sulfate DA Keire, ML Trehy, JC Reepmeyer, RE Kolinski, W Ye, J Dunn, ... Journal of pharmaceutical and biomedical analysis 51 (4), 921-926, 2010 | 81 | 2010 |
| Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics RG Brinson, JP Marino, F Delaglio, LW Arbogast, RM Evans, A Kearsley, ... MAbs 11 (1), 94-105, 2019 | 74 | 2019 |
| The conformation of substance P in lipid environments DA Keire, TG Fletcher Biophysical journal 70 (4), 1716-1727, 1996 | 69 | 1996 |
| Precision and robustness of 2D-NMR for structure assessment of filgrastim biosimilars H Ghasriani, DJ Hodgson, RG Brinson, I McEwen, LF Buhse, S Kozlowski, ... Nature biotechnology 34 (2), 139-141, 2016 | 68 | 2016 |
| The interaction of β‐amyloid protein fragment (12‐28) with lipid environments TG Fletcher, DA Keire Protein science 6 (3), 666-675, 1997 | 68 | 1997 |
| Diversifying the global heparin supply chain: reintroduction of bovine heparin in the United States? A Szajek, E Gray, D Keire, B Mulloy, A Al-Hakim, C Chase, MDLC Soares, ... Pharmaceutical Technology 39 (11), 2015 | 67 | 2015 |
| Structural comparison of two anti-CD20 monoclonal antibody drug products using middle-down mass spectrometry B Wang, AC Gucinski, DA Keire, LF Buhse, MT Boyne II Analyst 138 (10), 3058-3065, 2013 | 58 | 2013 |
| Characterization of currently marketed heparin products: reversed-phase ion-pairing liquid chromatography mass spectrometry of heparin digests AM Brustkern, LF Buhse, M Nasr, A Al-Hakim, DA Keire Analytical chemistry 82 (23), 9865-9870, 2010 | 56 | 2010 |
| A Cautionary Tale: Quantitative LC-HRMS Analytical Procedures for the Analysis of N-Nitrosodimethylamine in Metformin J Yang, W Ye, CD Sommers, JD Rodriguez, DA Keire The AAPS Journal 22, 1-8, 2020 | 51 | 2020 |
| Comparison of NMR and dynamic light scattering for measuring diffusion coefficients of formulated insulin: implications for particle size distribution measurements in drug products SM Patil, DA Keire, K Chen The AAPS journal 19, 1760-1766, 2017 | 51 | 2017 |
Michael T. Boyne IICo-founder and Principal, CatalystBioVerified email at catalystbio.co
