Balancing mTOR signaling and autophagy in the treatment of Parkinson’s disease Z Zhu, C Yang, A Iyaswamy, S Krishnamoorthi, SG Sreenivasmurthy, J Liu, ... International journal of molecular sciences 20 (3), 728, 2019 | 190 | 2019 |
Effects of Cissus quadrangularis on the proliferation, differentiation and matrix mineralization of human osteoblast like SaOS‐2 cells S Muthusami, K Senthilkumar, C Vignesh, R Ilangovan, J Stanley, ... Journal of Cellular Biochemistry 112 (4), 1035-1045, 2011 | 88 | 2011 |
Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy C Yang, C Su, A Iyaswamy, SK Krishnamoorthi, Z Zhu, S Yang, BC Tong, ... Acta Pharmaceutica Sinica B 12 (4), 1707-1722, 2022 | 60 | 2022 |
Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer’s disease mouse model RCL Ng, M Jian, OKF Ma, M Bunting, JSC Kwan, GJ Zhou, ... Molecular psychiatry 26 (10), 5669-5689, 2021 | 55 | 2021 |
A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38 C Yang, Z Zhu, BCK Tong, A Iyaswamy, WJ Xie, Y Zhu, ... Redox biology 32, 101445, 2020 | 45 | 2020 |
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models A Iyaswamy, X Wang, S Krishnamoorthi, V Kaliamoorthy, ... Redox biology 51, 102280, 2022 | 43 | 2022 |
Targeting aggrephagy for the treatment of Alzheimer’s disease S Malampati, JX Song, B Chun-Kit Tong, A Nalluri, CB Yang, Z Wang, ... Cells 9 (2), 311, 2020 | 43 | 2020 |
Cissus quadrangularis augments IGF system components in human osteoblast like SaOS-2 cells S Muthusami, I Ramachandran, S Krishnamoorthy, R Govindan, ... Growth Hormone & IGF Research 21 (6), 343-348, 2011 | 40 | 2011 |
Amyloid-β oligomer targeted theranostic probes for in vivo NIR imaging and inhibition of self-aggregation and amyloid-β induced ROS generation X Wang, C Wang, HN Chan, I Ashok, SK Krishnamoorthi, M Li, HW Li, ... Talanta 224, 121830, 2021 | 38 | 2021 |
Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease A Iyaswamy, SK Krishnamoorthi, H Zhang, SG Sreenivasmurthy, Z Zhu, ... Phytomedicine 91, 153648, 2021 | 37 | 2021 |
Di 2-ethyl hexyl phthalate affects differentiation and matrix mineralization of rat calvarial osteoblasts–in vitro FA Bhat, G Ramajayam, S Parameswari, RC Vignesh, S Karthikeyan, ... Toxicology in Vitro 27 (1), 250-256, 2013 | 37 | 2013 |
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition SG Sreenivasmurthy, A Iyaswamy, S Krishnamoorthi, S Senapati, ... Phytomedicine 96, 153887, 2022 | 34 | 2022 |
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease BCK Tong, AJ Wu, AS Huang, R Dong, S Malampati, A Iyaswamy, ... Autophagy 18 (3), 624-642, 2022 | 33 | 2022 |
NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models A Iyaswamy, SK Krishnamoorthi, JX Song, CB Yang, V Kaliyamoorthy, ... Journal of food and drug analysis 28 (1), 132-146, 2020 | 31 | 2020 |
Real-Time Detection and Visualization of Amyloid-β Aggregates Induced by Hydrogen Peroxide in Cell and Mouse Models of Alzheimer’s Disease ACS Appl. Mater. Interfaces, 2022 | 30 | 2022 |
Regulation of insulin-like growth factors and their binding proteins by thyroid stimulating hormone in human osteoblast-like (SaOS2) cells G Ramajayam, RC Vignesh, S Karthikeyan, K Senthil Kumar, ... Molecular and cellular biochemistry 368, 77-88, 2012 | 25 | 2012 |
Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy SG Sreenivasmurthy, A Iyaswamy, S Krishnamoorthi, RN Reddi, ... Frontiers in Molecular Biosciences 9, 1030534, 2022 | 23 | 2022 |
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Z Zhu, L Liu, C Su, J Liu, BCK Tong, A Iyaswamy, S Krishnamoorthi, ... Acta Pharmacologica Sinica 43 (10), 2511-2526, 2022 | 23 | 2022 |
Yuan-Hu Zhi tong prescription mitigates tau pathology and alleviates memory deficiency in the preclinical models of Alzheimer’s Disease A Iyaswamy, JX Song, AK Kammala, SG Sreenivasmurthy, S Malampati, ... Frontiers in Pharmacology 11, 584770, 2020 | 23 | 2020 |
Klotho an autophagy stimulator as a potential therapeutic target for Alzheimer’s disease: A review TY Fung, A Iyaswamy, SG Sreenivasmurthy, S Krishnamoorthi, XJ Guan, ... Biomedicines 10 (3), 705, 2022 | 22 | 2022 |