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Dr. Senthilkumar Krishnamoorthi
Dr. Senthilkumar Krishnamoorthi
Hong Kong Baptist University
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Year
Balancing mTOR signaling and autophagy in the treatment of Parkinson’s disease
Z Zhu, C Yang, A Iyaswamy, S Krishnamoorthi, SG Sreenivasmurthy, J Liu, ...
International journal of molecular sciences 20 (3), 728, 2019
1902019
Effects of Cissus quadrangularis on the proliferation, differentiation and matrix mineralization of human osteoblast like SaOS‐2 cells
S Muthusami, K Senthilkumar, C Vignesh, R Ilangovan, J Stanley, ...
Journal of Cellular Biochemistry 112 (4), 1035-1045, 2011
882011
Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology: Implications for Alzheimer's disease therapy
C Yang, C Su, A Iyaswamy, SK Krishnamoorthi, Z Zhu, S Yang, BC Tong, ...
Acta Pharmaceutica Sinica B 12 (4), 1707-1722, 2022
602022
Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer’s disease mouse model
RCL Ng, M Jian, OKF Ma, M Bunting, JSC Kwan, GJ Zhou, ...
Molecular psychiatry 26 (10), 5669-5689, 2021
552021
A stress response p38 MAP kinase inhibitor SB202190 promoted TFEB/TFE3-dependent autophagy and lysosomal biogenesis independent of p38
C Yang, Z Zhu, BCK Tong, A Iyaswamy, WJ Xie, Y Zhu, ...
Redox biology 32, 101445, 2020
452020
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models
A Iyaswamy, X Wang, S Krishnamoorthi, V Kaliamoorthy, ...
Redox biology 51, 102280, 2022
432022
Targeting aggrephagy for the treatment of Alzheimer’s disease
S Malampati, JX Song, B Chun-Kit Tong, A Nalluri, CB Yang, Z Wang, ...
Cells 9 (2), 311, 2020
432020
Cissus quadrangularis augments IGF system components in human osteoblast like SaOS-2 cells
S Muthusami, I Ramachandran, S Krishnamoorthy, R Govindan, ...
Growth Hormone & IGF Research 21 (6), 343-348, 2011
402011
Amyloid-β oligomer targeted theranostic probes for in vivo NIR imaging and inhibition of self-aggregation and amyloid-β induced ROS generation
X Wang, C Wang, HN Chan, I Ashok, SK Krishnamoorthi, M Li, HW Li, ...
Talanta 224, 121830, 2021
382021
Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease
A Iyaswamy, SK Krishnamoorthi, H Zhang, SG Sreenivasmurthy, Z Zhu, ...
Phytomedicine 91, 153648, 2021
372021
Di 2-ethyl hexyl phthalate affects differentiation and matrix mineralization of rat calvarial osteoblasts–in vitro
FA Bhat, G Ramajayam, S Parameswari, RC Vignesh, S Karthikeyan, ...
Toxicology in Vitro 27 (1), 250-256, 2013
372013
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition
SG Sreenivasmurthy, A Iyaswamy, S Krishnamoorthi, S Senapati, ...
Phytomedicine 96, 153887, 2022
342022
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease
BCK Tong, AJ Wu, AS Huang, R Dong, S Malampati, A Iyaswamy, ...
Autophagy 18 (3), 624-642, 2022
332022
NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models
A Iyaswamy, SK Krishnamoorthi, JX Song, CB Yang, V Kaliyamoorthy, ...
Journal of food and drug analysis 28 (1), 132-146, 2020
312020
Real-Time Detection and Visualization of Amyloid-β Aggregates Induced by Hydrogen Peroxide in Cell and Mouse Models of Alzheimer’s Disease
ACS Appl. Mater. Interfaces, 2022
302022
Regulation of insulin-like growth factors and their binding proteins by thyroid stimulating hormone in human osteoblast-like (SaOS2) cells
G Ramajayam, RC Vignesh, S Karthikeyan, K Senthil Kumar, ...
Molecular and cellular biochemistry 368, 77-88, 2012
252012
Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy
SG Sreenivasmurthy, A Iyaswamy, S Krishnamoorthi, RN Reddi, ...
Frontiers in Molecular Biosciences 9, 1030534, 2022
232022
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy
Z Zhu, L Liu, C Su, J Liu, BCK Tong, A Iyaswamy, S Krishnamoorthi, ...
Acta Pharmacologica Sinica 43 (10), 2511-2526, 2022
232022
Yuan-Hu Zhi tong prescription mitigates tau pathology and alleviates memory deficiency in the preclinical models of Alzheimer’s Disease
A Iyaswamy, JX Song, AK Kammala, SG Sreenivasmurthy, S Malampati, ...
Frontiers in Pharmacology 11, 584770, 2020
232020
Klotho an autophagy stimulator as a potential therapeutic target for Alzheimer’s disease: A review
TY Fung, A Iyaswamy, SG Sreenivasmurthy, S Krishnamoorthi, XJ Guan, ...
Biomedicines 10 (3), 705, 2022
222022
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