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Dr. Ashutosh Arun
Dr. Ashutosh Arun
CSIR-Central Drug Research Institute
Verified email at mmc.edu - Homepage
Title
Cited by
Cited by
Year
Synthesis of targeted dibenzo [b, f] thiepines and dibenzo [b, f] oxepines as potential lead molecules with promising anti-breast cancer activity
MI Ansari, MK Hussain, A Arun, B Chakravarti, R Konwar, K Hajela
European Journal of Medicinal Chemistry 99, 113-124, 2015
362015
Anti-colon cancer activity of Murraya koenigii leaves is due to constituent murrayazoline and O-methylmurrayamine A induced mTOR/AKT downregulation and mitochondrial apoptosis
A Arun, OPS Patel, D Saini, PP Yadav, R Konwar
Biomedicine & Pharmacotherapy 93, 510-521, 2017
322017
Bivalent approach for homodimeric estradiol based ligand: synthesis and evaluation for targeted theranosis of ER (+) breast carcinomas
K Chauhan, A Arun, S Singh, M Manohar, K Chuttani, R Konwar, ...
Bioconjugate Chemistry 27 (4), 961-972, 2016
232016
Design, synthesis and in vitro evaluation of coumarin–imidazo [1, 2-a] pyridine derivatives against cancer induced osteoporosis
KV Sashidhara, LR Singh, D Choudhary, A Arun, S Gupta, S Adhikary, ...
RSC Advances 6 (83), 80037-80048, 2016
222016
Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors
K Upadhyaya, Hamidullah, K Singh, A Arun, M Shukla, N Srivastava, ...
Organic & biomolecular chemistry 14 (4), 1338-1358, 2016
222016
Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of …
OPS Patel, A Arun, PK Singh, D Saini, SS Karade, MK Chourasia, ...
European journal of medicinal chemistry 167, 226-244, 2019
182019
piRNAs as modulators of disease pathogenesis
KJ Rayford, A Cooley, JT Rumph, A Arun, G Rachakonda, F Villalta, ...
International Journal of Molecular Sciences 22 (5), 2373, 2021
142021
New piperidine derivative DTPEP acts as dual‐acting anti‐breast cancer agent by targeting ER α and downregulating PI 3K/Akt‐PKC α leading to caspase‐dependent apoptosis
A Arun, MI Ansari, P Popli, S Jaiswal, AK Mishra, A Dwivedi, K Hajela, ...
Cell proliferation 51 (6), e12501, 2018
132018
Discovery of 3, 4, 6‐Triaryl‐2‐pyridones as potential anticancer agents that promote ROS‐independent mitochondrial‐mediated apoptosis in human breast carcinoma cells
MI Ansari, A Arun, MK Hussain, R Konwar, K Hajela
ChemistrySelect 1 (14), 4255-4264, 2016
82016
Trypanosoma cruzi Modulates PIWI-Interacting RNA Expression in Primary Human Cardiac Myocytes during the Early Phase of Infection
KJ Rayford, A Cooley, A Arun, G Rachakonda, Y Kleschenko, F Villalta, ...
International journal of molecular sciences 21 (24), 9439, 2020
62020
Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart …
A Arun, KJ Rayford, A Cooley, G Rachakonda, F Villalta, S Pratap, ...
International Journal of Molecular Sciences 21 (14), 4912, 2020
62020
Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells
A Arun, KJ Rayford, A Cooley, T Rana, G Rachakonda, F Villalta, S Pratap, ...
PLOS Neglected Tropical Diseases 16 (1), e0010074, 2022
22022
Xanthine Analogs Suppress Trypanosoma cruzi Infection In Vitro Using PDEs as Targets
AR Banga, KR Sekhar, KJ Rayford, A Arun, P Odiase, AP Garg, MF Lima, ...
Microbiology Research 13 (4), 721-739, 2022
2022
Trypanosoma cruzi dysregulates expression of piRNA that can regulate IL‐6 signaling in human cardiac fibroblasts during the early phase of infection
KJ Rayford, A Cooley, A Arun, G Rachakonda, F Villalta, MF Lima, ...
The FASEB Journal 36, 2022
2022
Analysis Pipeline of PIWI-Interacting RNA (piRNA) in an Inflammatory Parasitic Infectious Disease
A Cooley, K Rayford, A Arun, G Rachakonda, Y Kleschenko, F Villalta, ...
The FASEB Journal 35, 2021
2021
Thrombospondin-1 Plays an Essential Role in Hippo Signaling During the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells
A Arun, K Rayford, A Cooley, G Rachakonda, F Villalta, S Pratap, M Lima, ...
The FASEB Journal 35, 2021
2021
Dysregulation of piwi-interacting RNA expression in primary human cardiac myocytes during early phase of Trypanosoma cruzi infection
K Rayford, A Cooley, A Arun, G Rachakonda, Y Kleschenko, F Villalta, ...
The FASEB Journal 35, 2021
2021
Identification of new anti-colon cancer agents from leaves of Murraya koenigii
A Arun
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Articles 1–18