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Dr. Ashutosh Arun
Dr. Ashutosh Arun
CSIR-Central Drug Research Institute
Verified email at wustl.edu - Homepage
Title
Cited by
Cited by
Year
Anti-colon cancer activity of Murraya koenigii leaves is due to constituent murrayazoline and O-methylmurrayamine A induced mTOR/AKT downregulation and mitochondrial apoptosis
A Arun, OPS Patel, D Saini, PP Yadav, R Konwar
Biomedicine & Pharmacotherapy 93, 510-521, 2017
442017
Synthesis of targeted dibenzo [b, f] thiepines and dibenzo [b, f] oxepines as potential lead molecules with promising anti-breast cancer activity
MI Ansari, MK Hussain, A Arun, B Chakravarti, R Konwar, K Hajela
European Journal of Medicinal Chemistry 99, 113-124, 2015
422015
piRNAs as modulators of disease pathogenesis
KJ Rayford, A Cooley, JT Rumph, A Arun, G Rachakonda, F Villalta, ...
International Journal of Molecular Sciences 22 (5), 2373, 2021
312021
Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors
K Upadhyaya, Hamidullah, K Singh, A Arun, M Shukla, N Srivastava, ...
Organic & biomolecular chemistry 14 (4), 1338-1358, 2016
292016
Design, synthesis and in vitro evaluation of coumarin–imidazo [1, 2-a] pyridine derivatives against cancer induced osteoporosis
KV Sashidhara, LR Singh, D Choudhary, A Arun, S Gupta, S Adhikary, ...
RSC Advances 6 (83), 80037-80048, 2016
262016
Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of …
OPS Patel, A Arun, PK Singh, D Saini, SS Karade, MK Chourasia, ...
European journal of medicinal chemistry 167, 226-244, 2019
242019
Bivalent approach for homodimeric estradiol based ligand: synthesis and evaluation for targeted theranosis of ER (+) breast carcinomas
K Chauhan, A Arun, S Singh, M Manohar, K Chuttani, R Konwar, ...
Bioconjugate Chemistry 27 (4), 961-972, 2016
232016
New piperidine derivative DTPEP acts as dual‐acting anti‐breast cancer agent by targeting ER α and downregulating PI 3K/Akt‐PKC α leading to caspase‐dependent apoptosis
A Arun, MI Ansari, P Popli, S Jaiswal, AK Mishra, A Dwivedi, K Hajela, ...
Cell proliferation 51 (6), e12501, 2018
172018
Discovery of 3, 4, 6‐Triaryl‐2‐pyridones as potential anticancer agents that promote ROS‐independent mitochondrial‐mediated apoptosis in human breast carcinoma cells
MI Ansari, A Arun, MK Hussain, R Konwar, K Hajela
ChemistrySelect 1 (14), 4255-4264, 2016
112016
Trypanosoma cruzi Modulates PIWI-Interacting RNA Expression in Primary Human Cardiac Myocytes during the Early Phase of Infection
KJ Rayford, A Cooley, A Arun, G Rachakonda, Y Kleschenko, F Villalta, ...
International Journal of Molecular Sciences 21 (24), 9439, 2020
102020
Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart …
A Arun, KJ Rayford, A Cooley, G Rachakonda, F Villalta, S Pratap, ...
International Journal of Molecular Sciences 21 (14), 4912, 2020
92020
Trypanosoma cruzi dysregulates expression profile of piRNAs in primary human cardiac fibroblasts during early infection phase
KJ Rayford, A Cooley, AW Strode, I Osi, A Arun, MF Lima, S Misra, ...
Frontiers in Cellular and Infection Microbiology 13, 1083379, 2023
42023
Xanthine Analogs Suppress Trypanosoma cruzi Infection In Vitro Using PDEs as Targets
AR Banga, KR Sekhar, KJ Rayford, A Arun, P Odiase, AP Garg, MF Lima, ...
Microbiology Research 13 (4), 721-739, 2022
32022
Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells
A Arun, KJ Rayford, A Cooley, T Rana, G Rachakonda, F Villalta, S Pratap, ...
PLoS Neglected Tropical Diseases 16 (1), e0010074, 2022
32022
Trypanosoma cruzi dysregulates expression of piRNA that can regulate IL‐6 signaling in human cardiac fibroblasts during the early phase of infection
KJ Rayford, A Cooley, A Arun, G Rachakonda, F Villalta, MF Lima, ...
The FASEB Journal 36, 2022
12022
Trypanasoma cruzi dystegulates piRNA computationally predicted to target proinflammatory molecules in Primary Human Cardiac Myocytes during Early Infection Phase
A Cooley, K Rayford, A Arun, P Nde, S Pratap
Journal of Biological Chemistry 299 (3), S683, 2023
2023
Trypanosoma cruzi dysregulates piRNAs targeting IL-6 signaling pathway in primary human cardiac fibroblasts during acute infection
K Rayford, A Cooley, A Strode, I Osi, A Arun, S Pratap, P Nde
Journal of Biological Chemistry 299 (3), S48, 2023
2023
Trypanosoma cruzi Dysregulates piRNAs Computationally Predicted to Target IL-6 Signaling Molecules During Early Infection of Primary Human Cardiac Fibroblasts
A Cooley, KJ Rayford, A Arun, F Villalta, MF Lima, S Pratap, PN Nde
Immune Network 22 (6), 2022
2022
Analysis Pipeline of PIWI‐Interacting RNA (piRNA) in an Inflammatory Parasitic Infectious Disease
A Cooley, K Rayford, A Arun, G Rachakonda, Y Kleschenko, F Villalta, ...
The FASEB Journal 35, 2021
2021
Thrombospondin‐1 Plays an Essential Role in Hippo Signaling During the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells
A Arun, K Rayford, A Cooley, G Rachakonda, F Villalta, S Pratap, M Lima, ...
The FASEB Journal 35, 2021
2021
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