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Karan Saini, Ph.D
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Design and synthesis of new bioisosteres of spirooxindoles (MI-63/219) as anti-breast cancer agents
A Kumar, G Gupta, AK Bishnoi, R Saxena, KS Saini, R Konwar, S Kumar, ...
Bioorganic & Medicinal Chemistry 23 (4), 839-848, 2015
642015
Polymorphic variations in IL-1β, IL-6 and IL-10 genes, their circulating serum levels and breast cancer risk in Indian women
S Pooja, P Chaudhary, LV Nayak, S Rajender, KS Saini, D Deol, S Kumar, ...
Cytokine 60 (1), 122-128, 2012
642012
Saraca indica bark extract shows in vitro antioxidant, antibreast cancer activity and does not exhibit toxicological effects
NK Yadav, KS Saini, Z Hossain, A Omer, C Sharma, JR Gayen, P Singh, ...
Oxidative medicine and cellular longevity 2015, 2015
522015
Quercetin-6-C-β-D-glucopyranoside, natural analog of quercetin exhibits anti-prostate cancer activity by inhibiting Akt-mTOR pathway via aryl hydrocarbon receptor
R Kumar, KS Saini, A Kumar, S Kumar, E Ramakrishna, R Maurya, ...
Biochimie 119, 68-79, 2015
412015
Synthesis and biological evaluation of some novel triazole hybrids of curcumin mimics and their selective anticancer activity against breast and prostate cancer cell lines
D Mandalapu, KS Saini, S Gupta, V Sharma, MY Malik, S Chaturvedi, ...
Bioorganic & Medicinal Chemistry Letters 26 (17), 4223-4232, 2016
382016
Strong impact of TGF-β1 gene polymorphisms on breast cancer risk in Indian women: a case-control and population-based study
S Pooja, A Francis, S Rajender, R Tamang, R Rajkumar, KS Saini, ...
PLoS One 8 (10), e75979, 2013
372013
Chemotherapeutic potential of 2-[piperidinoethoxyphenyl]-3-phenyl-2H-benzo (b) pyran in estrogen receptor-negative breast cancer cells: action via prevention of EGFR activation …
R Saxena, V Chandra, M Manohar, K Hajela, U Debnath, YS Prabhakar, ...
PLoS One 8 (6), e66246, 2013
292013
Triazole analog 1-(1-benzyl-5-(4-chlorophenyl)-1H-1, 2, 3-triazol-4-yl)-2-(4-bromophenylamino)-1-(4-chlorophenyl) ethanol induces reactive oxygen species and autophagy …
KS Saini, A Ajay, N Devender, A Bhattacharjee, S Das, S Dwivedi, ...
The International Journal of Biochemistry & Cell Biology 65, 275-287, 2015
282015
Berberine represses β-catenin translation involving 4E-BPs in hepatocellular carcinoma cells
K Vishnoi, R Ke, KS Saini, N Viswakarma, RS Nair, S Das, Z Chen, ...
Molecular Pharmacology 99 (1), 1-16, 2021
162021
New orally active DNA minor groove binding small molecule CT‐1 acts against breast cancer by targeting tumor DNA damage leading to p53‐dependent apoptosis
KS Saini, Hamidullah, R Ashraf, D Mandalapu, S Das, MQ Siddiqui, ...
Molecular Carcinogenesis 56 (4), 1266-1280, 2017
162017
Novel alkylphospholipid-DTC hybrids as promising agents against endocrine related cancers acting via modulation of Akt-pathway
S Jangir, V Bala, N Lal, L Kumar, A Sarswat, A Kumar, KS Saini, ...
European Journal of Medicinal Chemistry 85, 638-647, 2014
162014
Monocyte chemoattractant protein‐1 gene polymorphism and its serum level have an impact on anthropometric and biochemical risk factors of metabolic syndrome in Indian population
AK Madeshiya, S Singh, S Dwivedi, KS Saini, R Singh, S Tiwari, ...
International Journal of Immunogenetics 42 (2), 78-86, 2015
82015
Saraca indica bark extract shows in vitro antioxidant, antibreast cancer activity and does not exhibit toxicological effects, Oxid. Med. Cell Longev. 2015 (2015), 205360
NK Yadav, KS Saini, Z Hossain, A Omer, C Sharma, JR Gayen, P Singh, ...
3
Elucidating the role of mixed lineage kinase 3 (MLK3)-β-catenin axis in hepatocellular carcinoma
KS Saini, T Gheewala, S Das, G Sondarva, A Rana, B Rana
Cancer Research 78 (13_Supplement), 3450-3450, 2018
2018
Strong impact of TGF-β1 gene polymorphisms on breast cancer risk in Indian women: a case-control and population-based study.
SP Singh Pooja, AF Amirtharaj Francis, SR Singh Rajender, ...
2013
Polymorphic variations in IL-1β, IL-6 and IL-10 genes, their circulating serum levels and breast cancer risk in Indian women.
SP Singh Pooja, PC Preeti Chaudhary, LV Nayak, SR Singh Rajender, ...
2012
5a-dihydrotestosterone (DHT) inhibits Tumor Necrosis Factor-alpha (TNF-a) induced Janus Kinase-1 (JNK-1) activation and apoptosis in breast cancer in p21 dependent manner
KS Saini, V Turkar, R Konwar
apoptosis 23, 25, 0
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Articles 1–17