DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed … C Szabó, B Zingarelli, M O'Connor, AL SALzMAN Proceedings of the National Academy of Sciences 93 (5), 1753-1758, 1996 | 802 | 1996 |
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite. C Szabó, S Cuzzocrea, B Zingarelli, M O'Connor, AL Salzman The Journal of clinical investigation 100 (3), 723-735, 1997 | 462 | 1997 |
Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury B Zingarelli, AL Salzman, C Szabó Circulation research 83 (1), 85-94, 1998 | 441 | 1998 |
Melatonin is a scavenger of peroxynitrite E Gilad, S Cuzzocrea, B Zingarelli, AL Salzman, C Szabó Life sciences 60 (10), PL169-PL174, 1997 | 427 | 1997 |
Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury Z Yang, B Zingarelli, C Szabó Circulation 101 (9), 1019-1026, 2000 | 421 | 2000 |
Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial … B Zingarelli, M O'Connor, H Wong, AL Salzman, C Szabó Journal of immunology (Baltimore, Md.: 1950) 156 (1), 350-358, 1996 | 376 | 1996 |
Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction K Essandoh, L Yang, X Wang, W Huang, D Qin, J Hao, Y Wang, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (11 …, 2015 | 375 | 2015 |
Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFκB activation E Gilad, HR Wong, B Zingarelli, L Virág, M O'connor, AL Salzman, ... The FASEB Journal 12 (9), 685-693, 1998 | 348 | 1998 |
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly (ADP-ribose) synthase C Szabó, L Virág, S Cuzzocrea, GS Scott, P Hake, MP O’Connor, ... Proceedings of the National Academy of Sciences 95 (7), 3867-3872, 1998 | 339 | 1998 |
Protective effect of melatonin in carrageenan‐induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite … S Cuzzocrea, B Zingarelli, E Gilad, P Hake, AL Salzman, C Szabó Journal of pineal research 23 (2), 106-116, 1997 | 330 | 1997 |
Exosomal miR-223 contributes to mesenchymal stem cell-elicited cardioprotection in polymicrobial sepsis X Wang, H Gu, D Qin, L Yang, W Huang, K Essandoh, Y Wang, ... Scientific reports 5 (1), 13721, 2015 | 322 | 2015 |
Nuclear factor-κB as a therapeutic target in critical care medicine B Zingarelli, M Sheehan, HR Wong Critical Care Medicine 31 (1), S105-S111, 2003 | 291 | 2003 |
Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation S Cuzzocrea, B Zingarelli, P Hake, AL Salzman, C Szabo Free Radical Biology and Medicine 24 (3), 450-459, 1998 | 282 | 1998 |
Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite C Szabó, B Zingarelli, AL Salzman Circulation Research 78 (6), 1051-1063, 1996 | 275 | 1996 |
Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects C Szabó, LHK Lim, S Cuzzocrea, SJ Getting, B Zingarelli, RJ Flower, ... The Journal of experimental medicine 186 (7), 1041-1049, 1997 | 269 | 1997 |
Peroxisome proliferator activator receptor-γ ligands, 15-deoxy-Δ12, 14-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of … B Zingarelli, M Sheehan, PW Hake, M O’Connor, A Denenberg, JA Cook The Journal of Immunology 171 (12), 6827-6837, 2003 | 265 | 2003 |
Epigallocatechin, a green tea polyphenol, attenuates myocardial ischemia reperfusion injury in rats R Aneja, PW Hake, TJ Burroughs, AG Denenberg, HR Wong, B Zingarelli Molecular Medicine 10, 55-62, 2004 | 263 | 2004 |
Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase B Zingarelli, S Cuzzocrea, Z Zsengellér, AL Salzman, C Szabó Cardiovascular research 36 (2), 205-215, 1997 | 255 | 1997 |
Minimum quality threshold in pre-clinical sepsis studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis MF Osuchowski, A Ayala, S Bahrami, M Bauer, M Boros, JM Cavaillon, ... Intensive care medicine experimental 6, 1-6, 2018 | 250 | 2018 |
Role of biomarkers in sepsis care RS Samraj, B Zingarelli, HR Wong Shock 40 (5), 358-365, 2013 | 223 | 2013 |