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Pamela Lockyer
Pamela Lockyer
Verified email at med.unc.edu
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Cited by
Year
CHIP deficiency decreases longevity, with accelerated aging phenotypes accompanied by altered protein quality control
JN Min, RA Whaley, NE Sharpless, P Lockyer, AL Portbury, C Patterson
Molecular and cellular biology 28 (12), 4018-4025, 2008
2922008
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteins
HH Li, MS Willis, P Lockyer, N Miller, H McDonough, DJ Glass, ...
The Journal of clinical investigation 117 (11), 3211-3223, 2007
2812007
LRP1-dependent endocytic mechanism governs the signaling output of the bmp system in endothelial cells and in angiogenesis
X Pi, CE Schmitt, L Xie, AL Portbury, Y Wu, P Lockyer, LA Dyer, M Moser, ...
Circulation research 111 (5), 564-574, 2012
792012
CHIP protects against cardiac pressure overload through regulation of AMPK
JC Schisler, CE Rubel, C Zhang, P Lockyer, DM Cyr, C Patterson
The Journal of clinical investigation 123 (8), 2013
782013
The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun
HH Li, J Du, YN Fan, ML Zhang, DP Liu, L Li, P Lockyer, EY Kang, ...
The American journal of pathology 178 (3), 1043-1058, 2011
682011
Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ
H Mao, P Lockyer, L Li, CM Ballantyne, C Patterson, L Xie, X Pi
Nature communications 8 (1), 14960, 2017
572017
MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition
L Xu, CC Yates, P Lockyer, L Xie, A Bevilacqua, J He, C Lander, ...
Journal of molecular and cellular cardiology 77, 86-101, 2014
522014
Carboxyl terminus of Hsp70‐interacting protein (CHIP) is required to modulate cardiac hypertrophy and attenuate autophagy during exercise
MS Willis, JN Min, S Wang, H McDonough, P Lockyer, KM Wadosky, ...
Cell biochemistry and function 31 (8), 724-735, 2013
502013
LRP1 regulates retinal angiogenesis by inhibiting PARP-1 activity and endothelial cell proliferation
H Mao, P Lockyer, WHD Townley-Tilson, L Xie, X Pi
Arteriosclerosis, thrombosis, and vascular biology 36 (2), 350-360, 2016
482016
NADPH oxidase–generated reactive oxygen species are required for stromal cell–derived factor-1α–stimulated angiogenesis
X Pi, L Xie, AL Portbury, S Kumar, P Lockyer, X Li, C Patterson
Arteriosclerosis, Thrombosis, and Vascular Biology 34 (9), 2023-2032, 2014
462014
Muscle ring finger 1 and muscle ring finger 2 are necessary but functionally redundant during developmental cardiac growth and regulate E2F1‐mediated gene expression in vivo
MS Willis, KM Wadosky, JE Rodríguez, JC Schisler, P Lockyer, EG Hilliard, ...
Cell biochemistry and function 32 (1), 39-50, 2014
462014
Minireview: Won’t get fooled again: the nonmetabolic roles of peroxisome proliferator-activated receptors (PPARs) in the heart
P Lockyer, JC Schisler, C Patterson, MS Willis
Molecular Endocrinology 24 (6), 1111-1119, 2010
432010
Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis
X Pi, P Lockyer, LA Dyer, JC Schisler, B Russell, S Carey, DT Sweet, ...
Arteriosclerosis, thrombosis, and vascular biology 32 (9), 2214-2222, 2012
412012
BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice
N Patel, P Masaratana, J Diaz-Castro, GO Latunde-Dada, A Qureshi, ...
Journal of Biological Chemistry 287 (6), 4099-4106, 2012
352012
LRP1-dependent BMPER signaling regulates lipopolysaccharide-induced vascular inflammation
P Lockyer, H Mao, Q Fan, L Li, LY Yu-Lee, NT Eissa, C Patterson, L Xie, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (8), 1524-1535, 2017
302017
Efficient In Vivo Selection of a Novel Tumor-Associated Peptide from a Phage Display Library
AN Veleva, DB Nepal, CB Frederick, J Schwab, P Lockyer, H Yuan, ...
Molecules 16 (1), 900-914, 2011
262011
Development of a new positron emission tomography tracer for targeting tumor angiogenesis: Synthesis, small animal imaging, and radiation dosimetry
C Patterson, CB Frederick, H Yuan, LA Dyer, P Lockyer, DS Lalush, ...
Molecules 18 (5), 5594-5610, 2013
242013
BMPER promotes epithelial-mesenchymal transition in the developing cardiac cushions
L Dyer, P Lockyer, Y Wu, A Saha, C Cyr, M Moser, X Pi, C Patterson
PLoS One 10 (9), e0139209, 2015
222015
BMPER regulates cardiomyocyte size and vessel density in vivo
MS Willis, LA Dyer, R Ren, P Lockyer, I Moreno-Miralles, JC Schisler, ...
Cardiovascular Pathology 22 (3), 228-240, 2013
212013
Recombinant human interleukin-11 treatment enhances collateral vessel growth after femoral artery ligation
J Aitsebaomo, S Srivastava, H Zhang, S Jha, Z Wang, S Winnik, ...
Arteriosclerosis, thrombosis, and vascular biology 31 (2), 306-312, 2011
192011
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