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Sachini Umedi Siriwardena
Sachini Umedi Siriwardena
Broad Institute of MIT and Harvard
Verified email at broadinstitute.org
Title
Cited by
Cited by
Year
A high-throughput platform to identify small-molecule inhibitors of CRISPR-Cas9
B Maji, SA Gangopadhyay, M Lee, M Shi, P Wu, R Heler, B Mok, D Lim, ...
Cell 177 (4), 1067-1079. e19, 2019
1642019
Functions and malfunctions of mammalian DNA-cytosine deaminases
SU Siriwardena, K Chen, AS Bhagwat
Chemical reviews 116 (20), 12688-12710, 2016
1262016
Phosphorylation-inducing chimeric small molecules
SU Siriwardena, DNP Munkanatta Godage, VM Shoba, S Lai, M Shi, ...
Journal of the American Chemical Society 142 (33), 14052-14057, 2020
1032020
Characterization of the catalytic domain of human APOBEC3B and the critical structural role for a conserved methionine
SU Siriwardena, TA Guruge, AS Bhagwat
Journal of molecular biology 427 (19), 3042-3055, 2015
392015
A tumor-promoting phorbol ester causes a large increase in APOBEC3A expression and a moderate increase in APOBEC3B expression in a normal human keratinocyte cell line without …
SU Siriwardena, MLW Perera, V Senevirathne, J Stewart, AS Bhagwat
Molecular and cellular biology 39 (1), e00238-18, 2019
242019
Chemical and optical control of CRISPR-associated nucleases
AE Modell, SU Siriwardena, VM Shoba, X Li, A Choudhary
Current Opinion in Chemical Biology 60, 113-121, 2020
112020
The functions and malfunctions of AID/APOBEC family deaminases: the known knowns and the known unknowns
S Siriwardena, K Chen, AS Bhagwat
Chemical reviews 116 (20), 12688, 2016
102016
Synthetic reprogramming of kinases expands cellular activities of proteins
VM Shoba, DNP Munkanatta Godage, SK Chaudhary, A Deb, ...
Angewandte Chemie 134 (29), e202202770, 2022
92022
APOBEC3 enzymes mediate efficacy of cisplatin and are epistatic with base excision repair and mismatch repair in platinum response
KL Conner, AN Shaik, KA Marshall, AM Floyd, E Ekinci, J Lindquist, ...
NAR cancer 2 (4), zcaa033, 2020
62020
Development and applications of chimera platforms for tyrosine phosphorylation
R Pergu, VM Shoba, SK Chaudhary, DNP Munkanatta Godage, A Deb, ...
ACS Central Science 9 (8), 1558-1566, 2023
52023
A Jumbo Phage Forms a Nucleus-like Compartment to Evade Bacterial Defense Systems
SU Siriwardena, AE Modell, A Choudhary
Biochemistry, 2020
22020
Bifunctional molecules for selective modification of target substrates
A Choudhary, V SHOBA, A Deb, T Nguyen, LAI Sophia, DM GODAGE, ...
12022
Bifunctional molecules for selective modification of target substrates
A Choudhary, V Shoba, A Deb, T Nguyen, LAI Sophia, DM GODAGE, ...
US Patent App. 17/999,364, 2024
2024
Multi-functional chimeric molecules
A Choudhary, LAI Sophia, V Shoba, P Kokkonda, DM GODAGE, ...
US Patent App. 17/791,811, 2023
2023
Small-Molecule Inhibitors of CRISPR-Cas9
D Trauner, M Reynders
Synfacts 15 (08), 0936, 2019
2019
Biochemical And Cellular Studies Of Apobec3 Family Dna-Cytosine Deaminases
SU Siriwardena
Wayne State University, 2018
2018
Inflammation, Innate Immunity, and APOBEC3 Family DNA-Cytosine Deaminases.
AS Bhagwat, SU Siriwardena
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 57, S56-S56, 2016
2016
Use of magnetic nanoparticles for the extraction of DNA
SU Siriwardena, KMN de Silva, NV Chandrasekharan, RM de Silva
Sri Lanka Association for the Advancement of Science (SLAAS) 67th Annual …, 2011
2011
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