Identification of potent, selective, and orally bioavailable small-molecule GSPT1/2 degraders from a focused library of cereblon modulators G Nishiguchi, F Keramatnia, J Min, Y Chang, B Jonchere, S Das, M Actis, ... Journal of medicinal chemistry 64 (11), 7296-7311, 2021 | 58 | 2021 |
Sensitive screening of abused drugs in dried blood samples using ultra-high-performance liquid chromatography-ion booster-quadrupole time-of-flight mass spectrometry D Chepyala, IL Tsai, HW Liao, GY Chen, HC Chao, CH Kuo Journal of Chromatography a 1491, 57-66, 2017 | 46 | 2017 |
Development and validation of a high-performance liquid chromatography-fluorescence detection method for the accurate quantification of colistin in human plasma D Chepyala, IL Tsai, HY Sun, SW Lin, CH Kuo Journal of Chromatography B 980, 48-54, 2015 | 40 | 2015 |
Degradation of Janus kinases in CRLF2-rearranged acute lymphoblastic leukemia Y Chang, J Min, JA Jarusiewicz, M Actis, S Yu-Chen Bradford, ... Blood, The Journal of the American Society of Hematology 138 (23), 2313-2326, 2021 | 38 | 2021 |
Improved dried blood spot-based metabolomics analysis by a postcolumn infused-internal standard assisted liquid chromatography-electrospray ionization mass spectrometry method D Chepyala, HC Kuo, KY Su, HW Liao, SY Wang, SR Chepyala, ... Analytical chemistry 91 (16), 10702-10712, 2019 | 16 | 2019 |
Using matrix-induced ion suppression combined with LC-MS/MS for quantification of trimethylamine-N-oxide, choline, carnitine and acetylcarnitine in dried blood spot samples WH Lu, HH Chiu, HC Kuo, GY Chen, D Chepyala, CH Kuo Analytica Chimica Acta 1149, 338214, 2021 | 14 | 2021 |
Preclinical evaluation of proteolytic targeting of LCK as a therapeutic approach in T cell acute lymphoblastic leukemia J Hu, J Jarusiewicz, G Du, G Nishiguchi, S Yoshimura, JC Panetta, Z Li, ... Science translational medicine 14 (659), eabo5228, 2022 | 11 | 2022 |
The orally bioavailable GSPT1/2 degrader SJ6986 exhibits in vivo efficacy in acute lymphoblastic leukemia Y Chang, F Keramatnia, PS Ghate, G Nishiguchi, Q Gao, I Iacobucci, ... Blood 142 (7), 629-642, 2023 | 7 | 2023 |
An on-spot internal standard addition approach for accurately determining colistin A and colistin B in dried blood spots using ultra high-performance liquid chromatography … IL Tsai, CH Kuo, HY Sun, YC Chuang, D Chepyala, SW Lin, YJ Tsai Journal of Pharmaceutical and Biomedical Analysis 145, 783-793, 2017 | 7 | 2017 |
MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma M Zuckermann, C He, J Andrews, R Sloan-Henry, B Bianski, J Xie, ... Neuro-Oncology 24 (Supplement_1), i169-i169, 2022 | 2 | 2022 |
Development of Proteolytic Targeting Chimeras to Target Lck in T-Cell Acute Lymphoblastic Leukemia J Hu, J Jarusiewicz, J Min, L Yang, D Chepyala, M Actis, L Rowland, G Du, ... Blood 138 (Supplement 1), 867-867, 2021 | 2 | 2021 |
Additive effects of TPMT and NUDT15 on thiopurine toxicity in children with acute lymphoblastic leukemia across multiethnic populations M Maillard, R Nishii, W Yang, K Hoshitsuki, D Chepyala, SHR Lee, ... JNCI: Journal of the National Cancer Institute, djae004, 2024 | | 2024 |
ALL-594 Preclinical Assessment of Dual FLT3 and BCL-2 Inhibition in Lineage Ambiguous Leukemia L Montefiori, I Iacobucci, A Budhraja, J Moore, R Baskin-Doerfler, ... Clinical Lymphoma Myeloma and Leukemia 23, S255-S256, 2023 | | 2023 |
POSTER: ALL-594 Preclinical Assessment of Dual FLT3 and BCL-2 Inhibition in Lineage Ambiguous Leukemia L Montefiori, I Iacobucci, A Budhraja, J Moore, R Baskin-Doerfler, ... Clinical Lymphoma Myeloma and Leukemia 23, S153, 2023 | | 2023 |
Poster: ALL-090 Highly Effective Combination of FLT3 and BCL2 Inhibitors in a Preclinical Model of Lineage Ambiguous Leukemia L Montefiori, I Iacobucci, A Budhraja, J Moore, R Baskin, R DeVries, ... Clinical Lymphoma Myeloma and Leukemia 22, S120, 2022 | | 2022 |
ALL-090 Highly Effective Combination of FLT3 and BCL2 Inhibitors in a Preclinical Model of Lineage Ambiguous Leukemia L Montefiori, A Budhraja, J Moore, R Baskin, R DeVries, E Backhaus, ... Clinical Lymphoma Myeloma and Leukemia 22, S193-S194, 2022 | | 2022 |
Induced proximity and proteolytic targeting of LCK as a novel therapeutic approach in T-cell leukemia J Hu, J Jarusiewicz, J Min, L Yang, D Chepyala, M Actis, G Du, B Smart, ... Cancer Research 82 (12_Supplement), 423-423, 2022 | | 2022 |