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Nagsen Gautam
Nagsen Gautam
Senior Scientist-ll (Clinical Pharmacology and DMPK, Arrowhead Pharmaceuticals, Inc.)
Verified email at arrowheadpharma.com
Title
Cited by
Cited by
Year
Sequential LASER ART and CRISPR treatments eliminate HIV-1 in a subset of infected humanized mice
PK Dash, R Kaminski, R Bella, H Su, S Mathews, TM Ahooyi, C Chen, ...
Nature communications 10 (1), 1-20, 2019
2932019
Quantitative analysis of endogenous compounds
R Thakare, YS Chhonker, N Gautam, JA Alamoudi, Y Alnouti
Journal of pharmaceutical and biomedical analysis 128, 426-437, 2016
2002016
Creation of a long-acting nanoformulated dolutegravir
B Sillman, AN Bade, PK Dash, B Bhargavan, T Kocher, S Mathews, H Su, ...
Nature communications 9 (1), 443, 2018
1112018
Species differences in bile acids I. Plasma and urine bile acid composition
R Thakare, JA Alamoudi, N Gautam, AD Rodrigues, Y Alnouti
Journal of applied toxicology 38 (10), 1323-1335, 2018
1022018
Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders
P Coiro, R Padmashri, A Suresh, E Spartz, G Pendyala, S Chou, Y Jung, ...
Brain, behavior, and immunity 50, 249-258, 2015
1012015
Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles
T Zhou, H Su, P Dash, Z Lin, BLD Shetty, T Kocher, A Szlachetka, ...
Biomaterials 151, 53-65, 2018
942018
A year-long extended release nanoformulated cabotegravir prodrug
TA Kulkarni, AN Bade, B Sillman, BLD Shetty, MS Wojtkiewicz, N Gautam, ...
Nature materials 19 (8), 910-920, 2020
832020
Preclinical pharmacokinetics and tissue distribution of long-acting nanoformulated antiretroviral therapy
N Gautam, U Roy, S Balkundi, P Puligujja, D Guo, N Smith, XM Liu, ...
Antimicrobial agents and chemotherapy 57 (7), 3110-3120, 2013
752013
Pharmacodynamic and antiretroviral activities of combination nanoformulated antiretrovirals in HIV-1–infected human peripheral blood lymphocyte–reconstituted mice
U Roy, JE McMillan, Y Alnouti, N Gautum, N Smith, S Balkundi, P Dash, ...
The Journal of infectious diseases 206 (10), 1577-1588, 2012
712012
Mononuclear phagocyte intercellular crosstalk facilitates transmission of cell-targeted nanoformulated antiretroviral drugs to human brain endothelial cells
GD Kanmogne, S Singh, U Roy, X Liu, JE McMillan, S Gorantla, ...
International journal of nanomedicine, 2373-2388, 2012
642012
Urinary bile acids as biomarkers for liver diseases I. Stability of the baseline profile in healthy subjects
SPR Bathena, R Thakare, N Gautam, S Mukherjee, M Olivera, J Meza, ...
Toxicological sciences 143 (2), 296-307, 2015
582015
Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugs
DP Gnanadhas, PK Dash, B Sillman, AN Bade, Z Lin, DL Palandri, ...
The Journal of clinical investigation 127 (3), 857-873, 2017
572017
Creation of a long-acting nanoformulated 2′, 3′-dideoxy-3′-thiacytidine
D Guo, T Zhou, M Araínga, D Palandri, N Gautam, T Bronich, Y Alnouti, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes 74 (3), e75-e83, 2017
552017
Development and characterization of a long-acting nanoformulated abacavir prodrug
D Singh, JE McMillan, J Hilaire, N Gautam, D Palandri, Y Alnouti, ...
Nanomedicine 11 (15), 1913-1927, 2016
542016
Species differences in bile acids II. Bile acid metabolism
R Thakare, JA Alamoudi, N Gautam, AD Rodrigues, Y Alnouti
Journal of applied toxicology 38 (10), 1336-1352, 2018
502018
UPLC–MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues
J Huang, N Gautam, SPR Bathena, U Roy, JE McMillan, HE Gendelman, ...
Journal of Chromatography B 879 (23), 2332-2338, 2011
472011
Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy
P Radhakrishnan, VC Bryant, EC Blowers, RN Rajule, N Gautam, ...
Clinical cancer research 19 (8), 2025-2035, 2013
402013
Peripherally cross-linking the shell of core-shell polymer micelles decreases premature release of physically loaded combretastatin A4 in whole blood and increases its mean …
RR Wakaskar, SPR Bathena, SB Tallapaka, VV Ambardekar, N Gautam, ...
Pharmaceutical research 32, 1028-1044, 2015
392015
Urinary bile acids as biomarkers for liver diseases II. Signature profiles in patients
SPR Bathena, R Thakare, N Gautam, S Mukherjee, M Olivera, J Meza, ...
Toxicological sciences 143 (2), 308-318, 2015
392015
Pharmacokinetics of a long-acting nanoformulated dolutegravir prodrug in rhesus macaques
JE McMillan, A Szlachetka, L Slack, B Sillman, B Lamberty, B Morsey, ...
Antimicrobial agents and chemotherapy 62 (1), 10.1128/aac. 01316-17, 2018
382018
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