Quantification of cefepime, meropenem, piperacillin, and tazobactam in human plasma using a sensitive and robust liquid chromatography-tandem mass spectrometry method, part 1 … R D'Cunha, T Bach, BA Young, P Li, D Nalbant, J Zhang, P Winokur, G An Antimicrobial agents and chemotherapy 62 (9), 10.1128/aac. 00859-18, 2018 | 51 | 2018 |
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: a randomized, placebo-controlled first-in-human single-dose escalation study G An, DJ Murry, K Gajurel, T Bach, G Deye, LV Stebounova, EE Codd, ... Antimicrobial agents and chemotherapy 63 (4), 10.1128/aac. 02255-18, 2019 | 42 | 2019 |
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy adults in an open-label phase 1 multiple ascending dose and food effect study T Bach, S Galbiati, JK Kennedy, G Deye, EYH Nomicos, EE Codd, ... Antimicrobial agents and chemotherapy 64 (11), 10.1128/aac. 01018-20, 2020 | 22 | 2020 |
Development and validation of a simple, fast, and sensitive LC/MS/MS method for the quantification of oxfendazole in human plasma and its application to clinical … T Bach, SH Bae, R D’Cunha, P Winokur, G An Journal of pharmaceutical and biomedical analysis 171, 111-117, 2019 | 13 | 2019 |
General pharmacokinetic features of small‐molecule compounds exhibiting target‐mediated drug disposition (TMDD): a simulation‐based study T Bach, Y Jiang, X Zhang, G An The Journal of Clinical Pharmacology 59 (3), 394-405, 2019 | 12 | 2019 |
Aspects of matrix and analyte effects in clinical pharmacokinetic sample analyses using LC-ESI/MS/MS–Two case examples G An, T Bach, I Abdallah, D Nalbant Journal of pharmaceutical and biomedical analysis 183, 113135, 2020 | 10 | 2020 |
Development and validation of a simple and sensitive LC-MS/MS method for the quantification of cefazolin in human plasma and its application to a clinical pharmacokinetic study JA Reeder, IA Abdallah, T Bach, CT O’Sullivan, Y Xu, D Nalbant, G An Journal of pharmaceutical and biomedical analysis 210, 114521, 2022 | 9 | 2022 |
Population pharmacokinetic model of oxfendazole and metabolites in healthy adults following single ascending doses T Bach, DJ Murry, LV Stebounova, G Deye, P Winokur, G An Antimicrobial agents and chemotherapy 65 (4), 10.1128/aac. 02129-20, 2021 | 6 | 2021 |
Importance of Utilizing Natural Isotopologue Transitions in Expanding the Linear Dynamic Range of LC-MS/MS Assay for Small-Molecule Pharmacokinetic Sample Analysis–A Mini-review T Bach, G An Journal of pharmaceutical sciences 111 (5), 1245-1249, 2022 | 3 | 2022 |
Population pharmacokinetic-pharmacodynamic model of oxfendazole in healthy adults in a multiple ascending dose and food effect study and target attainment analysis T Bach, GA Deye, EE Codd, J Horton, P Winokur, G An Antimicrobial agents and chemotherapy 66 (1), e01432-21, 2022 | 2 | 2022 |
Comparing the performance of first-order conditional estimation (FOCE) and different expectation–maximization (EM) methods in NONMEM: real data experience with complex … T Bach, G An Journal of pharmacokinetics and pharmacodynamics 48, 581-595, 2021 | 2 | 2021 |
Pharmacometric model of agalsidase–migalastat interaction in human: a novel mechanistic model of drug-drug interaction between a therapeutic protein and a small molecule T Bach, N Wu, G An Journal of pharmacokinetics and pharmacodynamics 50 (1), 63-74, 2023 | 1 | 2023 |
PHARMACOKINETICS, SAFETY, AND TOLERABILITY OF OXFENDAZOLE IN HEALTHY ADULTS IN AN OPEN LABEL PHASE 1 MULTIPLE ASCENDING DOSE AND FOOD EFFECT STUDY. T Bach, S Galbiati, J Kennedy, G Deye, E Nomicos, E Codd, H Garcia, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 109, S17-S17, 2021 | | 2021 |
Translation of Oxfendazole from Veterinary Medicine to Human for Antiparasitic and Anticancer Treatments – An Integrated in vitro, Clinical and Computational … HYT Bach The University of Iowa, 2021 | | 2021 |
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: a randomized, placebo-controlled first-in-human single-dose escalation study. AGH An GuoHua, DJ Murry, K Gajurel, T Bach, G Deye, LV Stebounova, ... | | 2019 |
Quantification of cefepime, meropenem, piperacillin, and tazobactam in human plasma using a sensitive and robust liquid chromatography-tandem mass spectrometry method, part 2 … R D'Cunha, T Bach, BA Young, P Li, D Nalbant, J Zhang, P Winokur, G An Antimicrobial agents and chemotherapy 62 (9), e00861-18, 2018 | | 2018 |
Calmodulin Bound Aquaporin-0 Reveals Two Distinct Energy Profiles LK Balcziak, TH Bach, LR Montgomery, ME Warwick, U Akgun Computational Molecular Bioscience 6 (04), 66, 2016 | | 2016 |