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Thanh Bach
Thanh Bach
Verified email at uiowa.edu
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Year
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: a randomized, placebo-controlled first-in-human single-dose escalation study
G An, DJ Murry, K Gajurel, T Bach, G Deye, LV Stebounova, EE Codd, ...
Antimicrobial agents and chemotherapy 63 (4), 10.1128/aac. 02255-18, 2019
422019
Quantification of cefepime, meropenem, piperacillin, and tazobactam in human plasma using a sensitive and robust liquid chromatography-tandem mass spectrometry method, part 1 …
R D'Cunha, T Bach, BA Young, P Li, D Nalbant, J Zhang, P Winokur, G An
Antimicrobial agents and chemotherapy 62 (9), 10.1128/aac. 00859-18, 2018
422018
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy adults in an open-label phase 1 multiple ascending dose and food effect study
T Bach, S Galbiati, JK Kennedy, G Deye, EYH Nomicos, EE Codd, ...
Antimicrobial agents and chemotherapy 64 (11), 10.1128/aac. 01018-20, 2020
212020
Development and validation of a simple, fast, and sensitive LC/MS/MS method for the quantification of oxfendazole in human plasma and its application to clinical …
T Bach, SH Bae, R D’Cunha, P Winokur, G An
Journal of pharmaceutical and biomedical analysis 171, 111-117, 2019
132019
General pharmacokinetic features of small‐molecule compounds exhibiting target‐mediated drug disposition (TMDD): a simulation‐based study
T Bach, Y Jiang, X Zhang, G An
The Journal of Clinical Pharmacology 59 (3), 394-405, 2019
122019
Aspects of matrix and analyte effects in clinical pharmacokinetic sample analyses using LC-ESI/MS/MS–Two case examples
G An, T Bach, I Abdallah, D Nalbant
Journal of pharmaceutical and biomedical analysis 183, 113135, 2020
102020
Development and validation of a simple and sensitive LC-MS/MS method for the quantification of cefazolin in human plasma and its application to a clinical pharmacokinetic study
JA Reeder, IA Abdallah, T Bach, CT O’Sullivan, Y Xu, D Nalbant, G An
Journal of pharmaceutical and biomedical analysis 210, 114521, 2022
92022
Population pharmacokinetic model of oxfendazole and metabolites in healthy adults following single ascending doses
T Bach, DJ Murry, LV Stebounova, G Deye, P Winokur, G An
Antimicrobial agents and chemotherapy 65 (4), 10.1128/aac. 02129-20, 2021
62021
Importance of Utilizing Natural Isotopologue Transitions in Expanding the Linear Dynamic Range of LC-MS/MS Assay for Small-Molecule Pharmacokinetic Sample Analysis–A Mini-review
T Bach, G An
Journal of pharmaceutical sciences 111 (5), 1245-1249, 2022
32022
Population pharmacokinetic-pharmacodynamic model of oxfendazole in healthy adults in a multiple ascending dose and food effect study and target attainment analysis
T Bach, GA Deye, EE Codd, J Horton, P Winokur, G An
Antimicrobial agents and chemotherapy 66 (1), e01432-21, 2022
22022
Comparing the performance of first-order conditional estimation (FOCE) and different expectation–maximization (EM) methods in NONMEM: real data experience with complex …
T Bach, G An
Journal of pharmacokinetics and pharmacodynamics 48, 581-595, 2021
22021
Pharmacometric model of agalsidase–migalastat interaction in human: a novel mechanistic model of drug-drug interaction between a therapeutic protein and a small molecule
T Bach, N Wu, G An
Journal of pharmacokinetics and pharmacodynamics 50 (1), 63-74, 2023
12023
PHARMACOKINETICS, SAFETY, AND TOLERABILITY OF OXFENDAZOLE IN HEALTHY ADULTS IN AN OPEN LABEL PHASE 1 MULTIPLE ASCENDING DOSE AND FOOD EFFECT STUDY.
T Bach, S Galbiati, J Kennedy, G Deye, E Nomicos, E Codd, H Garcia, ...
CLINICAL PHARMACOLOGY & THERAPEUTICS 109, S17-S17, 2021
2021
Translation of Oxfendazole from Veterinary Medicine to Human for Antiparasitic and Anticancer Treatments – An Integrated in vitro, Clinical and Computational …
HYT Bach
The University of Iowa, 2021
2021
Pharmacokinetics, safety, and tolerability of oxfendazole in healthy volunteers: a randomized, placebo-controlled first-in-human single-dose escalation study.
AGH An GuoHua, DJ Murry, K Gajurel, T Bach, G Deye, LV Stebounova, ...
2019
Quantification of cefepime, meropenem, piperacillin, and tazobactam in human plasma using a sensitive and robust liquid chromatography-tandem mass spectrometry method, part 2 …
R D'Cunha, T Bach, BA Young, P Li, D Nalbant, J Zhang, P Winokur, G An
Antimicrobial agents and chemotherapy 62 (9), e00861-18, 2018
2018
Calmodulin Bound Aquaporin-0 Reveals Two Distinct Energy Profiles
LK Balcziak, TH Bach, LR Montgomery, ME Warwick, U Akgun
Computational Molecular Bioscience 6 (04), 66, 2016
2016
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