|The epithelial-mesenchymal transition generates cells with properties of stem cells|
SA Mani, W Guo, MJ Liao, EN Eaton, A Ayyanan, AY Zhou, M Brooks, ...
Cell 133 (4), 704-715, 2008
|Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds|
D Huangfu, R Maehr, W Guo, A Eijkelenboom, M Snitow, AE Chen, ...
Nature biotechnology 26 (7), 795-797, 2008
|Integrin signalling during tumour progression|
W Guo, FG Giancotti
Nature reviews Molecular cell biology 5 (10), 816-826, 2004
|Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2|
D Huangfu, K Osafune, R Maehr, W Guo, A Eijkelenboom, S Chen, ...
Nature biotechnology 26 (11), 1269, 2008
|Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast|
C Scheel, EN Eaton, SHJ Li, CL Chaffer, F Reinhardt, KJ Kah, G Bell, ...
Cell 145 (6), 926-940, 2011
|Slug and Sox9 cooperatively determine the mammary stem cell state|
W Guo, Z Keckesova, JL Donaher, T Shibue, V Tischler, F Reinhardt, ...
Cell 148 (5), 1015-1028, 2012
|β4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis|
W Guo, Y Pylayeva, A Pepe, T Yoshioka, WJ Muller, G Inghirami, ...
Cell 126 (3), 489-502, 2006
|Integrin-specific activation of Rac controls progression through the G1 phase of the cell cycle|
A Mettouchi, S Klein, W Guo, M Lopez-Lago, E Lemichez, JK Westwick, ...
Molecular cell 8 (1), 115-127, 2001
|Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression|
CD May, N Sphyris, KW Evans, SJ Werden, W Guo, SA Mani
Breast Cancer Research 13 (1), 202, 2011
|Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells|
WL Tam, H Lu, J Buikhuisen, BS Soh, E Lim, F Reinhardt, ZJ Wu, JA Krall, ...
Cancer cell 24 (3), 347-364, 2013
|Integrin β4 signaling promotes tumor angiogenesis|
SN Nikolopoulos, P Blaikie, T Yoshioka, W Guo, FG Giancotti
Cancer cell 6 (5), 471-483, 2004
|Oncogene-dependent apoptosis is mediated by caspase-9|
HO Fearnhead, J Rodriguez, EE Govek, W Guo, R Kobayashi, G Hannon, ...
Proceedings of the National Academy of Sciences 95 (23), 13664-13669, 1998
|Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity|
MJ Liao, CC Zhang, B Zhou, DB Zimonjic, SA Mani, M Kaba, A Gifford, ...
Cancer research 67 (17), 8131-8138, 2007
|Targeted deletion of the integrin β4 signaling domain suppresses laminin-5-dependent nuclear entry of mitogen-activated protein kinases and NF-κB, causing defects in epidermal …|
SN Nikolopoulos, P Blaikie, T Yoshioka, W Guo, C Puri, C Tacchetti, ...
Molecular and cellular biology 25 (14), 6090-6102, 2005
|CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment|
P Wang, M Lin, E Pedrosa, A Hrabovsky, Z Zhang, W Guo, HM Lachman, ...
Molecular autism 6 (1), 55, 2015
|Prolyl isomerase Pin1 acts downstream of miR200c to promote cancer stem–like cell traits in breast cancer|
ML Luo, C Gong, CH Chen, DY Lee, H Hu, P Huang, Y Yao, W Guo, ...
Cancer research 74 (13), 3603-3616, 2014
|Lineage-biased stem cells maintain estrogen-receptor-positive and-negative mouse mammary luminal lineages|
C Wang, JR Christin, MH Oktay, W Guo
Cell reports 18 (12), 2825-2835, 2017
|Concise review: breast cancer stem cells: regulatory networks, stem cell niches, and disease relevance|
Stem cells translational medicine 3 (8), 942-948, 2014
|Alternative CD44 splicing in intestinal stem cells and tumorigenesis|
W Guo, PS Frenette
Oncogene 33 (5), 537-538, 2014
|Mammary-stem-cell-based somatic mouse models reveal breast cancer drivers causing cell fate dysregulation|
Z Zhang, JR Christin, C Wang, K Ge, MH Oktay, W Guo
Cell reports 16 (12), 3146-3156, 2016