| Human reduced folate carrier: translation of basic biology to cancer etiology and therapy LH Matherly, Z Hou, Y Deng Cancer and metastasis reviews 26, 111-128, 2007 | 346 | 2007 |
| The human proton-coupled folate transporter: Biology and therapeutic applications to cancer SK Desmoulin, Z Hou, A Gangjee, LH Matherly Cancer biology & therapy 13 (14), 1355-1373, 2012 | 208 | 2012 |
| Biology of the major facilitative folate transporters SLC19A1 and SLC46A1 Z Hou, LH Matherly Current topics in membranes 73, 175-204, 2014 | 151 | 2014 |
| Synthesis and Biological Activity of a Novel Series of 6-Substituted Thieno[2,3-d]pyrimidine Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate … Y Deng, X Zhou, S Kugel Desmoulin, J Wu, C Cherian, Z Hou, ... Journal of medicinal chemistry 52 (9), 2940-2951, 2009 | 120 | 2009 |
| The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer LH Matherly, MR Wilson, Z Hou Drug Metabolism and Disposition 42 (4), 632-649, 2014 | 104 | 2014 |
| Synthesis and discovery of high affinity folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity Y Deng, Y Wang, C Cherian, Z Hou, SA Buck, LH Matherly, A Gangjee Journal of medicinal chemistry 51 (16), 5052-5063, 2008 | 103 | 2008 |
| Structure and function of the reduced folate carrier: a paradigm of a major facilitator superfamily mammalian nutrient transporter LH Matherly, Z Hou Vitamins & hormones 79, 145-184, 2008 | 102 | 2008 |
| Synthesis and Antitumor Activity of a Novel Series of 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolate Inhibitors of Purine Biosynthesis with Selectivity for … L Wang, C Cherian, S Kugel Desmoulin, L Polin, Y Deng, J Wu, Z Hou, ... Journal of medicinal chemistry 53 (3), 1306-1318, 2010 | 92 | 2010 |
| Synthesis, Biological, and Antitumor Activity of a Highly Potent 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolate Inhibitor with Proton-Coupled Folate … L Wang, SK Desmoulin, C Cherian, L Polin, K White, J Kushner, A Fulterer, ... Journal of medicinal chemistry 54 (20), 7150-7164, 2011 | 90 | 2011 |
| Therapeutic targeting of a novel 6-substituted pyrrolo [2, 3-d] pyrimidine thienoyl antifolate to human solid tumors based on selective uptake by the proton-coupled folate … SK Desmoulin, L Wang, E Hales, L Polin, K White, J Kushner, M Stout, ... Molecular pharmacology 80 (6), 1096-1107, 2011 | 80 | 2011 |
| Synthesis and Biological Activity of 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Inhibitors of de Novo Purine Biosynthesis with Selectivity for … L Wang, C Cherian, S Kugel Desmoulin, S Mitchell-Ryan, Z Hou, ... Journal of medicinal chemistry 55 (4), 1758-1770, 2012 | 70 | 2012 |
| Targeting the proton-coupled folate transporter for selective delivery of 6-substituted pyrrolo [2, 3-d] pyrimidine antifolate inhibitors of de novo purine biosynthesis in the … SK Desmoulin, Y Wang, J Wu, M Stout, Z Hou, A Fulterer, MH Chang, ... Molecular pharmacology 78 (4), 577-587, 2010 | 65 | 2010 |
| Functional Analysis of Chimeric Proteins of the Wilson Cu (I)-ATPase (ATP7B) and ZntA, a Pb (II)/Zn (II)/Cd (II)-ATPase fromEscherichia coli Z Hou, S Narindrasorasak, B Bhushan, B Sarkar, B Mitra Journal of Biological Chemistry 276 (44), 40858-40863, 2001 | 64 | 2001 |
| The metal specificity and selectivity of ZntA from Escherichia coli using the acylphosphate intermediate Z Hou, B Mitra Journal of Biological Chemistry 278 (31), 28455-28461, 2003 | 60 | 2003 |
| 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human … L Wang, A Wallace, S Raghavan, SM Deis, MR Wilson, S Yang, L Polin, ... Journal of medicinal chemistry 58 (17), 6938-6959, 2015 | 55 | 2015 |
| Dual Targeting of Epithelial Ovarian Cancer Via Folate Receptor α and the Proton-Coupled Folate Transporter with 6-Substituted Pyrrolo[2,3-d]pyrimidine Antifolates Z Hou, L Gattoc, C O'Connor, S Yang, A Wallace-Povirk, C George, S Orr, ... Molecular cancer therapeutics 16 (5), 819-830, 2017 | 54 | 2017 |
| Discovery of 5-Substituted Pyrrolo[2,3-d]pyrimidine Antifolates as Dual-Acting Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4 … S Mitchell-Ryan, Y Wang, S Raghavan, MP Ravindra, E Hales, S Orr, ... Journal of medicinal chemistry 56 (24), 10016-10032, 2013 | 51 | 2013 |
| Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy AS Dekhne, K Shah, GS Ducker, JM Katinas, J Wong-Roushar, ... Molecular cancer therapeutics 18 (10), 1787-1799, 2019 | 47 | 2019 |
| Conserved Aspartic Acid 714 in Transmembrane Segment 8 of the ZntA Subgroup of P1B-Type ATPases Is a Metal-Binding Residue SJ Dutta, J Liu, Z Hou, B Mitra Biochemistry 45 (18), 5923-5931, 2006 | 47 | 2006 |
| Therapeutic targeting of mitochondrial one-carbon metabolism in cancer AS Dekhne, Z Hou, A Gangjee, LH Matherly Molecular cancer therapeutics 19 (11), 2245-2255, 2020 | 44 | 2020 |
Larry MatherlyKarmanos Cancer Institute/Wayne State UniversityVerified email at karmanos.org
