Jun-ichi Hanai
Jun-ichi Hanai
Instructor in Medicine, Harvard Medical School
Verified email at mgh.harvard.edu - Homepage
Cited by
Cited by
Soluble endoglin contributes to the pathogenesis of preeclampsia
S Venkatesha, M Toporsian, C Lam, J Hanai, T Mammoto, YM Kim, ...
Nature medicine 12 (6), 642-649, 2006
BMP-7 counteracts TGF-β1–induced epithelial-to-mesenchymal transition and reverses chronic renal injury
M Zeisberg, J Hanai, H Sugimoto, T Mammoto, D Charytan, F Strutz, ...
Nature medicine 9 (7), 964-968, 2003
Smad6 inhibits signalling by the TGF-β superfamily
T Imamura, M Takase, A Nishihara, E Oeda, J Hanai, M Kawabata, ...
Nature 389 (6651), 622-626, 1997
TGF‐β receptor‐mediated signalling through Smad2, Smad3 and Smad4
A Nakao, T Imamura, S Souchelnytskyi, M Kawabata, A Ishisaki, E Oeda, ...
The EMBO journal 16 (17), 5353-5362, 1997
Interaction and functional cooperation of PEBP2/CBF with smads synergistic induction of the immunoglobulin germline Cα promoter
J Hanai, LF Chen, T Kanno, N Ohtani-Fujita, WY Kim, WH Guo, T Imamura, ...
Journal of Biological Chemistry 274 (44), 31577-31582, 1999
c-Ski acts as a transcriptional co-repressor in transforming growth factor-β signaling through interaction with Smads
S Akiyoshi, H Inoue, J Hanai, K Kusanagi, N Nemoto, K Miyazono, ...
Journal of Biological Chemistry 274 (49), 35269-35277, 1999
A RUNX2/PEBP2αA/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia
YW Zhang, N Yasui, K Ito, G Huang, M Fujii, J Hanai, H Nogami, T Ochi, ...
Proceedings of the National Academy of Sciences 97 (19), 10549-10554, 2000
Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1
J Hanai, M Dhanabal, SA Karumanchi, C Albanese, M Waterman, B Chan, ...
Journal of biological chemistry 277 (19), 16464-16469, 2002
Cell surface glypicans are low-affinity endostatin receptors
SA Karumanchi, V Jha, R Ramchandran, A Karihaloo, L Tsiokas, B Chan, ...
Molecular cell 7 (4), 811-822, 2001
Targeting lactate dehydrogenase-a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells
H Xie, J Hanai, JG Ren, L Kats, K Burgess, P Bhargava, S Signoretti, ...
Cell metabolism 19 (5), 795-809, 2014
The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity
J Hanai, P Cao, P Tanksale, S Imamura, E Koshimizu, J Zhao, S Kishi, ...
The Journal of clinical investigation 117 (12), 3940-3951, 2007
Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA
S Miura, T Takeshita, H Asao, Y Kimura, K Murata, Y Sasaki, JI Hanai, ...
Molecular and cellular biology 20 (24), 9346-9355, 2000
Endostatin is a potential inhibitor of Wnt signaling
J Hanai, J Gloy, SA Karumanchi, S Kale, J Tang, G Hu, B Chan, ...
The Journal of cell biology 158 (3), 529-539, 2002
Role of p300, a transcriptional coactivator, in signalling of TGF‐β
A Nishihara, J Hanai, N Okamoto, J Yanagisawa, S Kato, K Miyazono, ...
Genes to Cells 3 (9), 613-623, 1998
Parathyroid hormone directs bone marrow mesenchymal cell fate
Y Fan, J Hanai, PT Le, R Bi, D Maridas, V DeMambro, CA Figueroa, S Kir, ...
Cell metabolism 25 (3), 661-672, 2017
Lipocalin 2 diminishes invasiveness and metastasis of Ras-transformed cells
J Hanai, T Mammoto, P Seth, K Mori, SA Karumanchi, J Barasch, ...
Journal of Biological Chemistry 280 (14), 13641-13647, 2005
Magic roundabout, a tumor endothelial marker: expression and signaling
P Seth, Y Lin, J Hanai, V Shivalingappa, MP Duyao, VP Sukhatme
Biochemical and biophysical research communications 332 (2), 533-541, 2005
E1A inhibits transforming growth factor-β signaling through binding to Smad proteins
A Nishihara, J Hanai, T Imamura, K Miyazono, M Kawabata
Journal of Biological Chemistry 274 (40), 28716-28723, 1999
Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen‐activated protein Kinase (MAPK) and Phosphatidylinositol‐3 …
J Hanai, N Doro, AT Sasaki, S Kobayashi, LC Cantley, P Seth, ...
Journal of cellular physiology 227 (4), 1709-1720, 2012
Statin‐induced muscle damage and atrogin‐1 induction is the result of a geranylgeranylation defect
P Cao, J Hanai, P Tanksale, S Imamura, VP Sukhatme, SH Lecker
The FASEB Journal 23 (9), 2844-2854, 2009
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