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Avital Beig
Avital Beig
Visiting Scholar, University of Michigan
Verified email at umich.edu
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Cited by
Year
A win–win solution in oral delivery of lipophilic drugs: supersaturation via amorphous solid dispersions increases apparent solubility without sacrifice of intestinal membrane …
JM Miller, A Beig, RA Carr, JK Spence, A Dahan
Molecular pharmaceutics 9 (7), 2009-2016, 2012
2682012
The solubility–permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation
JM Miller, A Beig, BJ Krieg, RA Carr, TB Borchardt, GE Amidon, ...
Molecular pharmaceutics 8 (5), 1848-1856, 2011
2062011
The solubility–permeability interplay and oral drug formulation design: Two heads are better than one
A Dahan, A Beig, D Lindley, JM Miller
Advanced drug delivery reviews 101, 99-107, 2016
1722016
The solubility–permeability interplay when using cosolvents for solubilization: revising the way we use solubility-enabling formulations
JM Miller, A Beig, RA Carr, GK Webster, A Dahan
Molecular pharmaceutics 9 (3), 581-590, 2012
1422012
Oral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulations
A Beig, R Agbaria, A Dahan
PLoS One 8 (7), e68237, 2013
1192013
Accounting for the solubility–permeability interplay in oral formulation development for poor water solubility drugs: the effect of PEG-400 on carbamazepine absorption
A Beig, JM Miller, A Dahan
European journal of pharmaceutics and biopharmaceutics 81 (2), 386-391, 2012
1162012
Head-to-head comparison of different solubility-enabling formulations of etoposide and their consequent solubility–permeability interplay
A Beig, JM Miller, D Lindley, RA Carr, P Zocharski, R Agbaria, A Dahan
Journal of pharmaceutical sciences 104 (9), 2941-2947, 2015
822015
In-situ intestinal rat perfusions for human Fabs prediction and BCS permeability class determination: Investigation of the single-pass vs. the Doluisio experimental approaches
I Lozoya-Agullo, M Zur, O Wolk, A Beig, I González-Álvarez, ...
International journal of pharmaceutics 480 (1-2), 1-7, 2015
812015
The twofold advantage of the amorphous form as an oral drug delivery practice for lipophilic compounds: increased apparent solubility and drug flux through the intestinal membrane
A Dahan, A Beig, V Ioffe-Dahan, R Agbaria, JM Miller
The AAPS journal 15, 347-353, 2013
802013
The use of captisol (SBE7-β-CD) in oral solubility-enabling formulations: Comparison to HPβCD and the solubility–permeability interplay
A Beig, R Agbaria, A Dahan
European Journal of Pharmaceutical Sciences 77, 73-78, 2015
612015
The interaction of nifedipine with selected cyclodextrins and the subsequent solubility–permeability trade-off
A Beig, JM Miller, A Dahan
European Journal of Pharmaceutics and Biopharmaceutics 85 (3), 1293-1299, 2013
602013
Hydrotropic solubilization of lipophilic drugs for oral delivery: the effects of urea and nicotinamide on carbamazepine solubility–permeability interplay
A Beig, D Lindley, JM Miller, R Agbaria, A Dahan
Frontiers in Pharmacology 7, 379, 2016
582016
Advantageous solubility-permeability interplay when using amorphous solid dispersion (ASD) formulation for the BCS class IV P-gp substrate rifaximin: simultaneous increase of …
A Beig, N Fine-Shamir, D Lindley, JM Miller, A Dahan
The AAPS journal 19, 806-813, 2017
572017
Segmental-dependent permeability throughout the small intestine following oral drug administration: Single-pass vs. Doluisio approach to in-situ rat perfusion
I Lozoya-Agullo, M Zur, A Beig, N Fine, Y Cohen, M González-Álvarez, ...
International journal of pharmaceutics 515 (1-2), 201-208, 2016
562016
Concomitant solubility-permeability increase: vitamin E TPGS vs. amorphous solid dispersion as oral delivery systems for etoposide
A Beig, N Fine-Shamir, D Porat, D Lindley, JM Miller, A Dahan
European Journal of Pharmaceutics and Biopharmaceutics 121, 97-103, 2017
492017
Toward successful cyclodextrin based solubility-enabling formulations for oral delivery of lipophilic drugs: solubility–permeability trade-off, biorelevant dissolution, and the …
N Fine-Shamir, A Beig, M Zur, D Lindley, JM Miller, A Dahan
Molecular pharmaceutics 14 (6), 2138-2146, 2017
472017
Striking the optimal solubility–permeability balance in oral formulation development for lipophilic drugs: maximizing carbamazepine blood levels
A Beig, JM Miller, D Lindley, A Dahan
Molecular pharmaceutics 14 (1), 319-327, 2017
382017
Characterization of attributes and in vitro performance of exenatide-loaded PLGA long-acting release microspheres
T Li, A Chandrashekar, A Beig, J Walker, JKY Hong, A Benet, J Kang, ...
European Journal of Pharmaceutics and Biopharmaceutics 158, 401-409, 2021
272021
Physical–chemical characterization of octreotide encapsulated in commercial glucose-star PLGA microspheres
A Beig, L Feng, J Walker, R Ackermann, JKY Hong, T Li, Y Wang, B Qin, ...
Molecular Pharmaceutics 17 (11), 4141-4151, 2020
242020
Segmental-dependent intestinal drug permeability: Development and model validation of in silico predictions guided by in vivo permeability values
O Wolk, M Markovic, D Porat, N Fine-Shamir, M Zur, A Beig, A Dahan
Journal of Pharmaceutical Sciences 108 (1), 316-325, 2019
202019
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