Structural characterization of IgG1 mAb aggregates and particles generated under various stress conditions SN Telikepalli, OS Kumru, C Kalonia, R Esfandiary, SB Joshi, ... Journal of pharmaceutical sciences 103 (3), 796-809, 2014 | 125 | 2014 |
Evaluating the role of the air-solution interface on the mechanism of subvisible particle formation caused by mechanical agitation for an IgG1 mAb S Ghazvini, C Kalonia, DB Volkin, P Dhar Journal of pharmaceutical sciences 105 (5), 1643-1656, 2016 | 72 | 2016 |
Comparison of polysorbate 80 hydrolysis and oxidation on the aggregation of a monoclonal antibody NR Larson, Y Wei, I Prajapati, A Chakraborty, B Peters, C Kalonia, ... Journal of Pharmaceutical Sciences 109 (1), 633-639, 2020 | 70 | 2020 |
Effects of protein conformation, apparent solubility, and protein–protein interactions on the rates and mechanisms of aggregation for an IgG1Monoclonal antibody C Kalonia, V Toprani, R Toth, N Wahome, I Gabel, CR Middaugh, ... The Journal of Physical Chemistry B 120 (29), 7062-7075, 2016 | 60 | 2016 |
Protein adsorption and layer formation at the stainless steel–solution interface mediates shear-induced particle formation for an IgG1 monoclonal antibody CK Kalonia, F Heinrich, JE Curtis, S Raman, MA Miller, SD Hudson Molecular pharmaceutics 15 (3), 1319-1331, 2018 | 59 | 2018 |
Calculating the mass of subvisible protein particles with improved accuracy using microflow imaging data C Kalonia, OS Kumru, VI Prajapati, R Mathaes, J Engert, S Zhou, ... Journal of pharmaceutical sciences 104 (2), 536-547, 2015 | 51 | 2015 |
Radar chart array analysis to visualize effects of formulation variables on IgG1 particle formation as measured by multiple analytical techniques C Kalonia, OS Kumru, JH Kim, CR Middaugh, DB Volkin Journal of pharmaceutical sciences 102 (12), 4256-4267, 2013 | 41 | 2013 |
Recent advances in studying interfacial adsorption of bioengineered monoclonal antibodies P Hollowell, Z Li, X Hu, S Ruane, C Kalonia, CF van der Walle, JR Lu Molecules 25 (9), 2047, 2020 | 23 | 2020 |
Understanding the stabilizing effect of histidine on mAb aggregation: a molecular dynamics study S Saurabh, C Kalonia, Z Li, P Hollowell, T Waigh, P Li, J Webster, ... Molecular Pharmaceutics 19 (9), 3288-3303, 2022 | 21 | 2022 |
The impact of the metal interface on the stability and quality of a therapeutic fusion protein AP Defante, CK Kalonia, E Keegan, SM Bishop, HA Satish, SD Hudson, ... Molecular Pharmaceutics 17 (2), 569-578, 2020 | 15 | 2020 |
Interfacial adsorption of a monoclonal antibody and its fab and fc fragments at the oil/water interface S Ruane, Z Li, M Campana, X Hu, H Gong, JRP Webster, F Uddin, ... Langmuir 35 (42), 13543-13552, 2019 | 15 | 2019 |
Cis/trans isomerization of unsaturated fatty acids in polysorbate 80 during light exposure of a monoclonal antibody–containing formulation I Prajapati, BH Peters, NR Larson, Y Wei, S Choudhary, C Kalonia, ... Journal of Pharmaceutical Sciences 109 (1), 603-613, 2020 | 14 | 2020 |
Investigating the Orientation of an Interfacially Adsorbed Monoclonal Antibody and Its Fragments Using Neutron Reflection S Ruane, Z Li, P Hollowell, A Hughes, J Warwicker, JRP Webster, ... Molecular Pharmaceutics 20 (3), 1643-1656, 2023 | 3 | 2023 |
Structure and interaction of therapeutic proteins in solution: a combined simulation and experimental study S Saurabh, Z Li, P Hollowell, T Waigh, P Li, J Webster, JM Seddon, ... Molecular Physics 121 (19-20), e2236248, 2023 | 2 | 2023 |
Competitive Adsorption of a Monoclonal Antibody and Nonionic Surfactant at the PDMS/Water Interface K Shen, X Hu, Z Li, M Liao, Z Zhuang, S Ruane, Z Wang, P Li, S Micciulla, ... Molecular Pharmaceutics 20 (5), 2502-2512, 2023 | 2 | 2023 |
Mechanistic Insights into the Adsorption of Monoclonal Antibodies at the Water/Vapor Interface S Saurabh, Q Zhang, Z Li, JM Seddon, C Kalonia, JR Lu, F Bresme Molecular Pharmaceutics 21 (2), 704-717, 2024 | 1 | 2024 |
Conformational changes and drivers of monoclonal antibody liquid-liquid phase separation NR Larson, Y Wei, TA Cruz, R Esfandiary, CK Kalonia, ML Forrest, ... Journal of pharmaceutical sciences 112 (3), 680-690, 2023 | 1 | 2023 |
Visible Light Degradation of a Monoclonal Antibody in a High-Concentration Formulation: Characterization of a Tryptophan-Derived Chromophoric Photo-product by Comparison to … I Prajapati, NR Larson, S Choudhary, C Kalonia, S Hudak, R Esfandiary, ... Molecular Pharmaceutics 18 (9), 3223-3234, 2021 | 1 | 2021 |
Unraveling the Microscopic Mechanism of Molecular Ion Interaction with Monoclonal Antibodies: Impact on Protein Aggregation S Saurabh, Q Zhang, JM Seddon, JR Lu, C Kalonia, F Bresme Molecular Pharmaceutics, 2024 | | 2024 |
The impact of the metal interface on the AP Defante, CK Kalonia, E Keegan, SM Bishop, HA Satish, SD Hudson | | |