CDK7 inhibition suppresses castration-resistant prostate cancer through MED1 inactivation R Rasool, R Natesan, Q Deng, S Aras, P Lal, S Sander Effron, ... Cancer discovery 9 (11), 1538-1555, 2019 | 93 | 2019 |
PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells B Rah, R Rasool, D Nayak, SK Yousuf, D Mukherjee, LD Kumar, ... Autophagy 11 (2), 314-331, 2015 | 88 | 2015 |
Targeting androgen regulation of TMPRSS2 and ACE2 as a therapeutic strategy to combat COVID-19 Q Deng, R ur Rasool, RM Russell, R Natesan, IA Asangani IScience 24 (3), 2021 | 67 | 2021 |
Design and synthesis of antitumor heck-coupled Sclareol analogues: modulation of BH3 family members by SS-12 in autophagy and apoptotic cell death B Rah, SH Lone, RU Rasool, S Farooq, D Nayak, NA Chikan, ... Journal of Medicinal Chemistry 58 (8), 3432-3444, 2015 | 47 | 2015 |
Par‐4 dependent modulation of cellular β‐catenin by medicinal plant natural product derivative 3‐azido Withaferin A H Amin, D Nayak, R ur Rasool, S Chakraborty, A Kumar, K Yousuf, ... Molecular Carcinogenesis 55 (5), 864-881, 2016 | 44 | 2016 |
Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cells D Nayak, A Kumar, S Chakraborty, H Amin, A Katoch, V Gopinath, ... Cell Death & Differentiation 24 (7), 1275-1287, 2017 | 40 | 2017 |
Convergence of therapy-induced senescence (TIS) and EMT in multistep carcinogenesis: current opinions and emerging perspectives MM Faheem, ND Seligson, SM Ahmad, RU Rasool, SG Gandhi, M Bhagat, ... Cell death discovery 6 (1), 51, 2020 | 39 | 2020 |
Dual role of Par‐4 in abrogation of EMT and switching on mesenchymal to epithelial transition (MET) in metastatic pancreatic cancer cells A Katoch, S Suklabaidya, S Chakraborty, D Nayak, RU Rasool, D Sharma, ... Molecular carcinogenesis 57 (9), 1102-1115, 2018 | 37 | 2018 |
Vimentin activation in early apoptotic cancer cells errands survival pathways during DNA damage inducer CPT treatment in colon carcinoma model S Chakraborty, A Kumar, MM Faheem, A Katoch, A Kumar, VL Jamwal, ... Cell Death & Disease 10 (6), 467, 2019 | 31 | 2019 |
Cristacarpin promotes ER stress-mediated ROS generation leading to premature senescence by activation of p21waf-1 S Chakraborty, RU Rasool, S Kumar, D Nayak, B Rah, A Katoch, H Amin, ... Age 38, 1-14, 2016 | 28 | 2016 |
Preparation, characterization and toxicological investigation of copper loaded chitosan nanoparticles in human embryonic kidney HEK-293 cells D Arora, V Dhanwal, D Nayak, A Saneja, H Amin, R ur Rasool, PN Gupta, ... Materials Science and Engineering: C 61, 227-234, 2016 | 28 | 2016 |
Inhibition of Invasion in Pancreatic Cancer Cells by Conjugate of EPA with β3,3-Pip-OH via PI3K/Akt/NF-kB Pathway H Amin, NA Wani, S Farooq, D Nayak, S Chakraborty, S Shankar, ... ACS Medicinal Chemistry Letters 6 (10), 1071-1074, 2015 | 25 | 2015 |
Dual modulation of Ras-Mnk and PI3K-AKT-mTOR pathways: a novel c-FLIP inhibitory mechanism of 3-AWA mediated translational attenuation through dephosphorylation of eIF4E R Ur Rasool, B Rah, H Amin, D Nayak, S Chakraborty, A Rawoof, ... Scientific Reports 6 (1), 18800, 2016 | 24 | 2016 |
AKT is indispensable for coordinating Par-4/JNK cross talk in p21 downmodulation during ER stress RU Rasool, D Nayak, S Chakraborty, MM Faheem, B Rah, P Mahajan, ... Oncogenesis 6 (5), e341-e341, 2017 | 21 | 2017 |
Differential regulation of NM23-H1 under hypoxic and serum starvation conditions in metastatic cancer cells and its implication in EMT RU Rasool, D Nayak, S Chakraborty, VL Jamwal, V Mahajan, A Katoch, ... European Journal of Cell Biology 96 (2), 164-171, 2017 | 21 | 2017 |
A therapeutically relevant, 3, 3′-diindolylmethane derivative NGD16 attenuates angiogenesis by targeting glucose regulated protein, 78 kDa (GRP78) D Nayak, H Amin, B Rah, R ur Rasool, D Sharma, AP Gupta, M Kushwaha, ... Chemico-Biological Interactions 232, 58-67, 2015 | 21 | 2015 |
A new class of bactericidal agents against S. aureus, MRSA and VRE derived from bisindolylmethane DK Sharma, AK Tripathi, R Sharma, R Chib, R ur Rasool, A Hussain, ... Medicinal Chemistry Research 23, 1643-1653, 2014 | 21 | 2014 |
Par-4 mediated Smad4 induction in PDAC cells restores canonical TGF-β/Smad4 axis driving the cells towards lethal EMT MM Faheem, R ur Rasool, SM Ahmad, VL Jamwal, S Chakraborty, ... European Journal of Cell Biology 99 (4), 151076, 2020 | 20 | 2020 |
Alkyne–azide cycloaddition analogues of dehydrozingerone as potential anti-prostate cancer inhibitors via the PI3K/Akt/NF-kB pathway C Kumar, RU Rasool, Z Iqra, Y Nalli, P Dutt, NK Satti, N Sharma, ... MedChemComm 8 (11), 2115-2124, 2017 | 18 | 2017 |
Reprogramming of molecular switching events in upr driven er stress: Scope for development of anticancer therapeutics B Rah, D Nayak, R Rasool, S Chakraborty, A Katoch, H Amin, A Goswami Current Molecular Medicine 16 (8), 690-701, 2016 | 15 | 2016 |