Erik Procko
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Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2
KK Chan, D Dorosky, P Sharma, SA Abbasi, JM Dye, DM Kranz, ...
Science 369 (6508), 1261-1265, 2020
The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity
PV Lishko, E Procko, X Jin, CB Phelps, R Gaudet
Neuron 54 (6), 905-918, 2007
Chromatin remodeling, measured by a novel real-time polymerase chain reaction assay, across the proximal promoter region of the IL-2 gene
S Rao, E Procko, MF Shannon
The Journal of Immunology 167 (8), 4494-4503, 2001
The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter
E Procko, ML O'Mara, WFD Bennett, DP Tieleman, R Gaudet
The FASEB Journal 23 (5), 1287-1302, 2009
Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter
E Procko, I Ferrin-O'Connell, SL Ng, R Gaudet
Molecular cell 24 (1), 51-62, 2006
A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells
E Procko, GY Berguig, BW Shen, Y Song, S Frayo, AJ Convertine, ...
Cell 157 (7), 1644-1656, 2014
An engineered decoy receptor for SARS-CoV-2 broadly binds protein S sequence variants
KK Chan, TJC Tan, KK Narayanan, E Procko
Science Advances 7 (8), eabf1738, 2021
Distinct properties of Ca2+–calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel
SY Lau, E Procko, R Gaudet
Journal of General Physiology 140 (5), 541-555, 2012
Computational design of a protein-based enzyme inhibitor
E Procko, R Hedman, K Hamilton, J Seetharaman, SJ Fleishman, M Su, ...
Journal of molecular biology 425 (18), 3563-3575, 2013
Structural and energetic basis of folded-protein transport by the FimD usher
S Geibel, E Procko, SJ Hultgren, D Baker, G Waksman
Nature 496 (7444), 243-246, 2013
Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel
H Inada, E Procko, M Sotomayor, R Gaudet
Biochemistry 51 (31), 6195-6206, 2012
Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer
S Berger, E Procko, D Margineantu, EF Lee, BW Shen, A Zelter, DA Silva, ...
elife 5, e20352, 2016
The sequence of human ACE2 is suboptimal for binding the S spike protein of SARS coronavirus 2
E Procko
BioRxiv, 2020
Identification of domain boundaries within the N‐termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin‐mediated increase in peptide loading of MHC class I
E Procko, G Raghuraman, DC Wiley, M Raghavan, R Gaudet
Immunology and cell biology 83 (5), 475-482, 2005
Engineered ACE2 decoy mitigates lung injury and death induced by SARS-CoV-2 variants
L Zhang, S Dutta, S Xiong, M Chan, KK Chan, TM Fan, KL Bailey, ...
Nature chemical biology 18 (3), 342-351, 2022
Mapping interaction sites on human chemokine receptors by deep mutational scanning
JD Heredia, J Park, RJ Brubaker, SK Szymanski, KS Gill, E Procko
The Journal of Immunology 200 (11), 3825-3839, 2018
Antigen processing and presentation: TAPping into ABC transporters
E Procko, R Gaudet
Current opinion in immunology 21 (1), 84-91, 2009
Leukocytes on the move with phosphoinositide 3‐kinase and its downstream effectors
E Procko, SR McColl
Bioessays 27 (2), 153-163, 2005
Structural architecture of a dimeric class C GPCR based on co-trafficking of sweet taste receptor subunits
J Park, B Selvam, K Sanematsu, N Shigemura, D Shukla, E Procko
Journal of Biological Chemistry 294 (13), 4759-4774, 2019
Identifying mutation hotspots reveals pathogenetic mechanisms of KCNQ2 epileptic encephalopathy
J Zhang, EC Kim, C Chen, E Procko, S Pant, K Lam, J Patel, R Choi, ...
Scientific reports 10 (1), 4756, 2020
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