Nishith Gupta
Nishith Gupta
Intracellular Parasite Education And Research Labs (iPEARL) @ BITS Hyderabad
Verified email at - Homepage
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Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes
A He, L Zhu, N Gupta, Y Chang, F Fang
Molecular endocrinology 21 (11), 2785-2794, 2007
PGC-1β-Regulated mitochondrial biogenesis and function in myotubes is mediated by NRF-1 and ERRα
D Shao, Y Liu, X Liu, L Zhu, Y Cui, A Cui, A Qiao, X Kong, Y Liu, Q Chen, ...
Mitochondrion 10 (5), 516-527, 2010
Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis
M Blume, D Rodriguez-Contreras, S Landfear, T Fleige, D Soldati-Favre, ...
Proceedings of the National Academy of Sciences 106 (31), 12998-13003, 2009
Selective disruption of phosphatidylcholine metabolism of the intracellular parasite Toxoplasma gondii arrests its growth
N Gupta, MM Zahn, I Coppens, KA Joiner, DR Voelker
Journal of Biological Chemistry 280 (16), 16345-16353, 2005
A Toxoplasma gondii gluconeogenic enzyme contributes to robust central carbon metabolism and is essential for replication and virulence
M Blume, R Nitzsche, U Sternberg, M Gerlic, SL Masters, N Gupta, ...
Cell host & microbe 18 (2), 210-220, 2015
Metabolic cooperation of glucose and glutamine is essential for the lytic cycle of obligate intracellular parasite Toxoplasma gondii
R Nitzsche, V Zagoriy, R Lucius, N Gupta
Journal of Biological Chemistry 291 (1), 126-141, 2016
Phosphatidylthreonine and lipid-mediated control of parasite virulence
RD Arroyo-Olarte, JF Brouwers, A Kuchipudi, JB Helms, A Biswas, ...
PLoS biology 13 (11), e1002288, 2015
Cell surface display of functionally active lipases from Yarrowia lipolytica in Pichia pastoris
ZB Jiang, HT Song, N Gupta, LX Ma, ZB Wu
Protein expression and purification 56 (1), 35-39, 2007
Proteomics-based identification of differentially-expressed proteins including galectin-1 in the blood plasma of type 2 diabetic patients
XJ Liu, QP Feng, Y Chen, J Zuo, N Gupta, YS Chang, FD Fang
Journal of Proteome Research 8 (3), 1255-1262, 2009
Toxoplasma gondii cyclic AMP-dependent protein kinase subunit 3 is involved in the switch from tachyzoite to bradyzoite development
T Sugi, YF Ma, T Tomita, F Murakoshi, MS Eaton, R Yakubu, B Han, V Tu, ...
MBio 7 (3), 10.1128/mbio. 00755-16, 2016
A constitutive pan-hexose permease for the Plasmodium life cycle and transgenic models for screening of antimalarial sugar analogs
M Blume, M Hliscs, D Rodriguez-Contreras, M Sanchez, S Landfear, ...
The FASEB Journal 25 (4), 1218, 2011
Pyruvate homeostasis as a determinant of parasite growth and metabolic plasticity in Toxoplasma gondii
N Xia, S Ye, X Liang, P Chen, Y Zhou, R Fang, J Zhao, N Gupta, S Yang, ...
MBio 10 (3), 10.1128/mbio. 00898-19, 2019
Influence of Eimeria falciformis infection on gut microbiota and metabolic pathways in mice
G Huang, S Zhang, C Zhou, X Tang, C Li, C Wang, X Tang, J Suo, Y Jia, ...
Infection and immunity 86 (5), 10.1128/iai. 00073-18, 2018
Phosphatidylethanolamine synthesis in the parasite mitochondrion is required for efficient growth but dispensable for survival of Toxoplasma gondii
A Hartmann, M Hellmund, R Lucius, DR Voelker, N Gupta
Journal of Biological Chemistry 289 (10), 6809-6824, 2014
The obligate intracellular parasite Toxoplasma gondii secretes a soluble phosphatidylserine decarboxylase
N Gupta, A Hartmann, R Lucius, DR Voelker
Journal of Biological Chemistry 287 (27), 22938-22947, 2012
Optogenetic modulation of an adenylate cyclase in Toxoplasma gondii demonstrates a requirement of the parasite cAMP for host-cell invasion and stage differentiation
A Hartmann, RD Arroyo-Olarte, K Imkeller, P Hegemann, R Lucius, ...
Journal of Biological Chemistry, 2013
Acquisition of exogenous fatty acids renders apicoplast-based biosynthesis dispensable in tachyzoites of Toxoplasma
X Liang, J Cui, X Yang, N Xia, Y Li, J Zhao, N Gupta, B Shen
Journal of Biological Chemistry 295 (22), 7743-7752, 2020
Eimeria falciformis infection of the mouse caecum identifies opposing roles of IFNγ-regulated host pathways for the parasite development
M Schmid, E Heitlinger, S Spork, HJ Mollenkopf, R Lucius, N Gupta
Mucosal Immunology 7 (4), 969-982, 2014
The intracellular parasite Toxoplasma gondii harbors three druggable FNT-type formate and l-lactate transporters in the plasma membrane
H Erler, B Ren, N Gupta, E Beitz
Journal of Biological Chemistry 293 (45), 17622-17630, 2018
Apicomplexan parasite, Eimeria falciformis, co-opts host tryptophan catabolism for life cycle progression in mouse
M Schmid, MJ Lehmann, R Lucius, N Gupta
Journal of Biological Chemistry 287 (24), 20197-20207, 2012
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