Nirav Dhanesha
Nirav Dhanesha
Assistant Professor, LSUHS, Shreveport
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Endothelial cell–derived von Willebrand factor is the major determinant that mediates von Willebrand factor–dependent acute ischemic stroke by promoting postischemic thrombo …
N Dhanesha, P Prakash, P Doddapattar, I Khanna, MJ Pollpeter, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (9), 1829-1837, 2016
Fibronectin splicing variants containing extra domain a promote atherosclerosis in mice through toll-like receptor 4
P Doddapattar, C Gandhi, P Prakash, N Dhanesha, IM Grumbach, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (11), 2391-2400, 2015
Inhibition of the methionine aminopeptidase 2 enzyme for the treatment of obesity
AA Joharapurkar, NA Dhanesha, MR Jain
Diabetes, metabolic syndrome and obesity: targets and therapy, 73-84, 2014
Discovery of potent, selective and orally bioavailable triaryl-sulfonamide based PTP1B inhibitors
D Patel, M Jain, SR Shah, R Bahekar, P Jadav, A Joharapurkar, ...
Bioorganic & medicinal chemistry letters 22 (2), 1111-1117, 2012
PKM2 promotes neutrophil activation and cerebral thromboinflammation: therapeutic implications for ischemic stroke
N Dhanesha, RB Patel, P Doddapattar, M Ghatge, GD Flora, M Jain, ...
Blood, The Journal of the American Society of Hematology 139 (8), 1234-1245, 2022
Smooth muscle cell–specific fibronectin-EDA mediates phenotypic switching and neointimal hyperplasia
M Jain, N Dhanesha, P Doddapattar, MR Chorawala, MK Nayak, ...
The Journal of clinical investigation 130 (1), 295-314, 2020
Endothelial cell–derived von Willebrand factor, but not platelet-derived, promotes atherosclerosis in apolipoprotein E–deficient mice
P Doddapattar, N Dhanesha, MR Chorawala, C Tinsman, M Jain, ...
Arteriosclerosis, thrombosis, and vascular biology 38 (3), 520-528, 2018
Myeloid cell PKM2 deletion enhances efferocytosis and reduces atherosclerosis
P Doddapattar, R Dev, M Ghatge, RB Patel, M Jain, N Dhanesha, ...
Circulation research 130 (9), 1289-1305, 2022
11 β-Hydroxysteroid dehydrogenase type 1: potential therapeutic target for metabolic syndrome
A Joharapurkar, N Dhanesha, G Shah, R Kharul, M Jain
Pharmacological reports 64 (5), 1055-1065, 2012
Deletion of a neuronal Drp1 activator protects against cerebral ischemia
KH Flippo, Z Lin, AS Dickey, X Zhou, NA Dhanesha, GC Walters, Y Liu, ...
Journal of Neuroscience 40 (15), 3119-3129, 2020
Dichloroacetate, an inhibitor of pyruvate dehydrogenase kinases, inhibits platelet aggregation and arterial thrombosis
MK Nayak, N Dhanesha, P Doddapattar, O Rodriguez, VK Sonkar, ...
Blood advances 2 (15), 2029-2038, 2018
Genetic ablation of extra domain A of fibronectin in hypercholesterolemic mice improves stroke outcome by reducing thrombo-inflammation
N Dhanesha, A Ahmad, P Prakash, P Doddapattar, SR Lentz, ...
Circulation 132 (23), 2237-2247, 2015
Exendin-4 reduces glycemia by increasing liver glucokinase activity: an insulin independent effect
N Dhanesha, A Joharapurkar, G Shah, V Dhote, S Kshirsagar, R Bahekar, ...
Pharmacological Reports 64 (1), 140-149, 2012
Exendin‐4 ameliorates diabetic symptoms through activation of glucokinase
N Dhanesha, A Joharapurkar, G Shah, V Dhote, S Kshirsagar, R Bahekar, ...
Journal of diabetes 4 (4), 369-377, 2012
Co-agonist of glucagon and GLP-1 reduces cholesterol and improves insulin sensitivity independent of its effect on appetite and body weight in diet-induced obese C57 mice
V Patel, A Joharapurkar, N Dhanesha, S Kshirsagar, K Patel, R Bahekar, ...
Canadian Journal of Physiology and Pharmacology 91 (12), 1009-1015, 2013
Targeting myeloid-specific integrin α9β1 improves short-and long-term stroke outcomes in murine models with preexisting comorbidities by limiting thrombosis and inflammation
N Dhanesha, M Jain, AK Tripathi, P Doddapattar, M Chorawala, G Bathla, ...
Circulation research 126 (12), 1779-1794, 2020
Protein methionine oxidation augments reperfusion injury in acute ischemic stroke
SX Gu, IO Blokhin, KM Wilson, N Dhanesha, P Doddapattar, IM Grumbach, ...
JCI insight 1 (7), 2016
Orally active osteoanabolic agent GTDF binds to adiponectin receptors, with a preference for AdipoR1, induces adiponectin-associated signaling, and improves metabolic health in …
AK Singh, AA Joharapurkar, MP Khan, JS Mishra, N Singh, M Yadav, ...
Diabetes 63 (10), 3530-3544, 2014
Inhibition of microsomal triglyceride transfer protein improves insulin sensitivity and reduces atherogenic risk in Zucker fatty rats
V Dhote, A Joharapurkar, S Kshirsagar, N Dhanesha, V Patel, A Patel, ...
Clinical and Experimental Pharmacology and Physiology 38 (5), 338-344, 2011
Targeting myeloid-cell specific integrin α9β1 inhibits arterial thrombosis in mice
N Dhanesha, MK Nayak, P Doddapattar, M Jain, GD Flora, S Kon, ...
Blood, The Journal of the American Society of Hematology 135 (11), 857-861, 2020
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