Design, synthesis, molecular docking and cytotoxic evaluation of novel 2-furybenzimidazoles as VEGFR-2 inhibitors MA Abdullaziz, HT Abdel-Mohsen, AM El Kerdawy, FAF Ragab, MM Ali, ... European journal of medicinal chemistry 136, 315-329, 2017 | 93 | 2017 |
Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1 … W Eldehna, S Abou-Seri, AM El Kerdawy, RR Ayyad, AM Hamdy, ... European Journal of Medicinal Chemistry 113, 50-62, 2016 | 79 | 2016 |
New thiazol-hydrazono-coumarin hybrids targeting human cervical cancer cells: Synthesis, CDK2 inhibition, QSAR and molecular docking studies SS Abd El-Karim, YM Syam, AM El Kerdawy, TM Abdelghany Bioorganic chemistry 86, 80-96, 2019 | 68 | 2019 |
Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors EM Gedawy, AE Kassab, AM El Kerdawy European Journal of Medicinal Chemistry 189, 112066, 2020 | 67 | 2020 |
Directional noncovalent interactions: repulsion and dispersion A El Kerdawy, JS Murray, P Politzer, P Bleiziffer, A Hesselmann, ... Journal of Chemical Theory and Computation 9 (5), 2264-2275, 2013 | 67 | 2013 |
Design and Synthesis of some new 2, 4, 6-trisubstituted quinazoline EGFR inhibitors as targeted anticancer agents HA Allam, EE Aly, AK Farouk, AM El Kerdawy, E Rashwan, SES Abbass Bioorganic Chemistry 98, 103726, 2020 | 56 | 2020 |
Type IIA-Type IIB protein tyrosine kinase inhibitors hybridization as an efficient approach for potent multikinase inhibitor development: Design, synthesis, anti-proliferative … WM Eldehna, AM El Kerdawy, GH Al-Ansary, ST Al-Rashood, MM Ali, ... European Journal of Medicinal Chemistry 163, 37-53, 2019 | 56 | 2019 |
Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer: design, synthesis, biological evaluation, and in silico studies WM Eldehna, ST Al-Rashood, T Al-Warhi, RO Eskandrani, A Alharbi, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 271-286, 2021 | 55 | 2021 |
Synthesis and anticonvulsant activity of certain substituted furochromone, benzofuran and flavone derivatives FAF Ragab, NAM El-Sayed, AAHM Eissa, AM El Kerdawy Chemical and Pharmaceutical Bulletin 58 (9), 1148-1156, 2010 | 46 | 2010 |
Synthesis, biological evaluation and in silico studies of certain oxindole–indole conjugates as anticancer CDK inhibitors T Al-Warhi, AM El Kerdawy, N Aljaeed, OE Ismael, RR Ayyad, ... Molecules 25 (9), 2031, 2020 | 42 | 2020 |
Novel potent substituted 4-amino-2-thiopyrimidines as dual VEGFR-2 and BRAF kinase inhibitors HT Abdel-Mohsen, MA Omar, AM El Kerdawy, AEE Mahmoud, MM Ali, ... European Journal of Medicinal Chemistry 179, 707-722, 2019 | 40 | 2019 |
Targeting receptor tyrosine kinase VEGFR-2 in hepatocellular cancer: rational design, synthesis and biological evaluation of 1, 2-disubstituted benzimidazoles HT Abdel-Mohsen, MA Abdullaziz, AM El Kerdawy, FAF Ragab, ... Molecules 25 (4), 770, 2020 | 39 | 2020 |
Anticancer activities, molecular docking and structure–activity relationship of novel synthesized 4H-chromene, and 5H-chromeno[2,3-d]pyrimidine candidates AH Halawa, MM Elaasser, AM El Kerdawy, AMAI Abd El-Hady, HA Emam, ... Medicinal Chemistry Research 26, 2624-2638, 2017 | 36 | 2017 |
Identification of the beer component hordenine as food-derived dopamine D2 receptor agonist by virtual screening a 3D compound database T Sommer, H Hübner, A El Kerdawy, P Gmeiner, M Pischetsrieder, T Clark Scientific reports 7 (1), 44201, 2017 | 35 | 2017 |
Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights MM Al-Sanea, A Elkamhawy, S Paik, K Lee, AM El Kerdawy, BSN Abbas, ... Bioorganic & medicinal chemistry 28 (13), 115525, 2020 | 31 | 2020 |
Design, synthesis, and molecular docking of novel 2‐arylbenzothiazole multiangiokinase inhibitors targeting breast cancer HT Abdel‐Mohsen, EA Abd El‐Meguid, AM El Kerdawy, AEE Mahmoud, ... Archiv der Pharmazie 353 (4), 1900340, 2020 | 29 | 2020 |
Novel benzothiazole-based dual VEGFR-2/EGFR inhibitors targeting breast and liver cancers: Synthesis, cytotoxic activity, QSAR and molecular docking studies EA Abd El-Meguid, AM Naglah, GO Moustafa, HM Awad, AM El Kerdawy Bioorganic & Medicinal Chemistry Letters 58, 128529, 2022 | 27 | 2022 |
Some 1, 3, 5-trisubstituted pyrazoline derivatives targeting breast cancer: Design, synthesis, cytotoxic activity, EGFR inhibition and molecular docking RF George, M Kandeel, DY El-Ansary, AM El Kerdawy Bioorganic Chemistry 99, 103780, 2020 | 27 | 2020 |
Receptor-based pharmacophore modeling, virtual screening, and molecular docking studies for the discovery of novel GSK-3β inhibitors AM El Kerdawy, AA Osman, MA Zaater Journal of Molecular Modeling 25, 1-21, 2019 | 26 | 2019 |
Quantum mechanics-based properties for 3D-QSAR A El Kerdawy, S Güssregen, H Matter, M Hennemann, T Clark Journal of chemical information and modeling 53 (6), 1486-1502, 2013 | 24 | 2013 |