| The α2δ-1-NMDA receptor complex is critically involved in neuropathic pain development and gabapentin therapeutic actions J Chen, L Li, SR Chen, H Chen, JD Xie, RE Sirrieh, DM MacLean, ... Cell reports 22 (9), 2307-2321, 2018 | 244 | 2018 |
| Dynamic membrane protein topological switching upon changes in phospholipid environment H Vitrac, DM MacLean, V Jayaraman, M Bogdanov, W Dowhan Proceedings of the National Academy of Sciences 112 (45), 13874-13879, 2015 | 89 | 2015 |
| Stargazin modulation of AMPA receptors SA Shaikh, DM Dolino, G Lee, S Chatterjee, DM MacLean, C Flatebo, ... Cell reports 17 (2), 328-335, 2016 | 62 | 2016 |
| Role of conformational dynamics in α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor partial agonism S Ramaswamy, D Cooper, N Poddar, DM MacLean, A Rambhadran, ... Journal of Biological Chemistry 287 (52), 43557-43564, 2012 | 58 | 2012 |
| Stargazin promotes closure of the AMPA receptor ligand-binding domain DM MacLean, SS Ramaswamy, M Du, JR Howe, V Jayaraman Journal of General Physiology 144 (6), 503-512, 2014 | 57 | 2014 |
| Ancestral reconstruction of the ligand-binding pocket of Family CG protein-coupled receptors D Kuang, Y Yao, D MacLean, M Wang, DR Hampson, BSW Chang Proceedings of the National Academy of Sciences 103 (38), 14050-14055, 2006 | 57 | 2006 |
| The structure–energy landscape of NMDA receptor gating DM Dolino, S Chatterjee, DM MacLean, C Flatebo, LDC Bishop, ... Nature chemical biology 13 (12), 1232-1238, 2017 | 51 | 2017 |
| Amino-terminal domain tetramer organization and structural effects of zinc binding in the N-methyl-D-aspartate (NMDA) receptor RE Sirrieh, DM MacLean, V Jayaraman Journal of Biological Chemistry 288 (31), 22555-22564, 2013 | 50 | 2013 |
| Coupling structure with function in acid‐sensing ion channels: challenges in pursuit of proton sensors ML Rook, M Musgaard, DM MacLean The Journal of physiology 599 (2), 417-430, 2021 | 44 | 2021 |
| Na+/Cl− dipole couples agonist binding to kainate receptor activation AYC Wong, DM MacLean, D Bowie Journal of Neuroscience 27 (25), 6800-6809, 2007 | 41 | 2007 |
| Proton-mediated conformational changes in an acid-sensing ion channel SS Ramaswamy, DM MacLean, AA Gorfe, V Jayaraman Journal of Biological Chemistry 288 (50), 35896-35903, 2013 | 40 | 2013 |
| Subtype-dependent N-methyl-D-aspartate receptor amino-terminal domain conformations and modulation by spermine RE Sirrieh, DM MacLean, V Jayaraman Journal of Biological Chemistry 290 (20), 12812-12820, 2015 | 37 | 2015 |
| A conserved structural mechanism of NMDA receptor inhibition: A comparison of ifenprodil and zinc RE Sirrieh, DM MacLean, V Jayaraman Journal of General Physiology 146 (2), 173-181, 2015 | 35 | 2015 |
| Comparing the performance of mScarlet-I, mRuby3, and mCherry as FRET acceptors for mNeonGreen TW McCullock, DM MacLean, PJ Kammermeier PloS one 15 (2), e0219886, 2020 | 33 | 2020 |
| β11-12 linker isomerization governs acid-sensing ion channel desensitization and recovery ML Rook, A Williamson, JD Lueck, M Musgaard, DM Maclean Elife 9, e51111, 2020 | 32 | 2020 |
| Conformational spread and dynamics in allostery of NMDA receptors RJ Durham, N Paudyal, E Carrillo, NK Bhatia, DM Maclean, V Berka, ... Proceedings of the National Academy of Sciences 117 (7), 3839-3847, 2020 | 31 | 2020 |
| Transmembrane AMPA receptor regulatory protein regulation of competitive antagonism: a problem of interpretation DM MacLean, D Bowie The Journal of physiology 589 (22), 5383-5390, 2011 | 31 | 2011 |
| Mechanism of Modulation of AMPA Receptors by TARPγ8 E Carrillo, SA Shaikh, V Berka, LM Nowak, V Jayaraman Biophysical Journal 118 (3), 191a, 2020 | 29 | 2020 |
| Dual effects of TARP γ-2 on glutamate efficacy can account for AMPA receptor autoinactivation ID Coombs, DM MacLean, V Jayaraman, M Farrant, SG Cull-Candy Cell reports 20 (5), 1123-1135, 2017 | 29 | 2017 |
| Dynamic lipid-dependent modulation of protein topology by post-translational phosphorylation H Vitrac, DM MacLean, A Karlstaedt, H Taegtmeyer, V Jayaraman, ... Journal of Biological Chemistry 292 (5), 1613-1624, 2017 | 28 | 2017 |
Derek BowieMcGill UniversityVerified email at mcgill.ca
Derek BowieMcGill UniversityVerified email at mcgill.ca