The Genome of the African Trypanosome Trypanosoma brucei M Berriman, E Ghedin, C Hertz-Fowler, G Blandin, H Renauld, ... science 309 (5733), 416-422, 2005 | 1971 | 2005 |
A novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies N Aboulaich, WK Chung, JH Thompson, C Larkin, D Robbins, M Zhu Biotechnology progress 30 (5), 1114-1124, 2014 | 133 | 2014 |
Structural insights into single-stranded DNA binding and cleavage by F factor TraI S Datta, C Larkin, JF Schildbach Structure 11 (11), 1369-1379, 2003 | 121 | 2003 |
Using fluorophore-labeled oligonucleotides to measure affinities of protein–DNA interactions BJ Anderson, C Larkin, K Guja, JF Schildbach Methods in enzymology 450, 253-272, 2008 | 117 | 2008 |
Inter-and intramolecular determinants of the specificity of single-stranded DNA binding and cleavage by the F factor relaxase C Larkin, S Datta, MJ Harley, BJ Anderson, A Ebie, V Hargreaves, ... Structure 13 (10), 1533-1544, 2005 | 107 | 2005 |
The sequence and analysis of Trypanosoma brucei chromosome II NMA El‐Sayed, E Ghedin, J Song, A MacLeod, F Bringaud, C Larkin, ... Nucleic acids research 31 (16), 4856-4863, 2003 | 87 | 2003 |
The hybrid search: a mass spectral library search method for discovery of modifications in proteomics MC Burke, YA Mirokhin, DV Tchekhovskoi, SP Markey, ... Journal of proteome research 16 (5), 1924-1935, 2017 | 68 | 2017 |
Subdomain organization and catalytic residues of the F factor TraI relaxase domain LM Street, MJ Harley, JC Stern, C Larkin, SL Williams, DL Miller, JA Dohm, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1646 (1-2), 86-99, 2003 | 54 | 2003 |
Recombinant HA1 produced in E. coli forms functional oligomers and generates strain-specific SRID potency antibodies for pandemic influenza vaccines S Khurana, C Larkin, S Verma, MB Joshi, J Fontana, AC Steven, LR King, ... Vaccine 29 (34), 5657-5665, 2011 | 49 | 2011 |
Rapid identification of biotherapeutics with label-free Raman spectroscopy SK Paidi, S Siddhanta, R Strouse, JB McGivney, C Larkin, I Barman Analytical chemistry 88 (8), 4361-4368, 2016 | 39 | 2016 |
Capillary zone electrophoresis tandem mass spectrometry detects low concentration host cell impurities in monoclonal antibodies G Zhu, L Sun, J Heidbrink‐Thompson, S Kuntumalla, H Lin, CJ Larkin, ... Electrophoresis 37 (4), 616-622, 2016 | 34 | 2016 |
Roles of active site residues and the HUH motif of the F plasmid TraI relaxase C Larkin, RJF Haft, MJ Harley, B Traxler, JF Schildbach Journal of biological chemistry 282 (46), 33707-33713, 2007 | 30 | 2007 |
Comprehensive analysis of host cell impurities in monoclonal antibodies with improved sensitivity by capillary zone electrophoresis mass spectrometry Z Zhang, T Albanetti, T Linkous, CJ Larkin, R Schoner, JB McGivney IV, ... Electrophoresis 38 (3-4), 401-407, 2017 | 27 | 2017 |
An intrastrand three-DNA-base interaction is a key specificity determinant of F transfer initiation and of F TraI relaxase DNA recognition and cleavage K Hekman, K Guja, C Larkin, JF Schildbach Nucleic acids research 36 (14), 4565-4572, 2008 | 23 | 2008 |
Storage conditions of conjugated reagents can impact results of immunogenicity assays RJ Kubiak, N Lee, Y Zhu, WR Franch, SV Levitskaya, SR Krishnan, ... Journal of Immunology Research 2016, 2016 | 22 | 2016 |
Crystallization and preliminary X-ray characterization of the relaxase domain of F factor TraI C Larkin, S Datta, A Nezami, JA Dohm, JF Schildbach Acta Crystallographica Section D: Biological Crystallography 59 (8), 1514-1516, 2003 | 15 | 2003 |
Quantitative analysis of the supernatant from host and transfected CHO cells using iTRAQ 8‐plex technique G Zhu, L Sun, T Albanetti, T Linkous, C Larkin, R Schoner, ... Biotechnology and Bioengineering 113 (10), 2140-2148, 2016 | 13 | 2016 |
A rapid lateral flow immunoassay for identity testing of biotherapeutics LA Machiesky, O Côté, LH Kirkegaard, SC Mefferd, C Larkin Journal of immunological methods 474, 112666, 2019 | 8 | 2019 |
Strategy for generating sequence-defined aptamer reagent sets for detecting protein contaminants in biotherapeutics JB McGivney IV, AT Csordas, FM Walker, ER Bagley, EM Gruber, ... Analytical chemistry 90 (5), 3262-3269, 2018 | 8 | 2018 |
Evaluation of continuous nonaffinity capture chromatography for a recombinant enzyme—optimization for a changing perfusion feedstream and comparison to batch processing C Thompson, K Wilson, C Larkin, J Lee, WK Wang, M Wendeler Biotechnology Progress 34 (5), 1195-1204, 2018 | 2 | 2018 |