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C Larkin
C Larkin
Unknown affiliation
Verified email at medimmune.com
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Cited by
Year
The Genome of the African Trypanosome Trypanosoma brucei
M Berriman, E Ghedin, C Hertz-Fowler, G Blandin, H Renauld, ...
science 309 (5733), 416-422, 2005
19062005
A novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies
N Aboulaich, WK Chung, JH Thompson, C Larkin, D Robbins, M Zhu
Biotechnology Progress 30 (5), 1114-1124, 2014
1122014
Structural insights into single-stranded DNA binding and cleavage by F factor TraI
S Datta, C Larkin, JF Schildbach
Structure 11 (11), 1369-1379, 2003
1112003
Using fluorophore-labeled oligonucleotides to measure affinities of protein–DNA interactions
BJ Anderson, C Larkin, K Guja, JF Schildbach
Methods in enzymology 450, 253-272, 2008
1032008
Inter-and intramolecular determinants of the specificity of single-stranded DNA binding and cleavage by the F factor relaxase
C Larkin, S Datta, MJ Harley, BJ Anderson, A Ebie, V Hargreaves, ...
Structure 13 (10), 1533-1544, 2005
1012005
The sequence and analysis of Trypanosoma brucei chromosome II
NMA El‐Sayed, E Ghedin, J Song, A MacLeod, F Bringaud, C Larkin, ...
Nucleic acids research 31 (16), 4856-4863, 2003
872003
The hybrid search: a mass spectral library search method for discovery of modifications in proteomics
MC Burke, YA Mirokhin, DV Tchekhovskoi, SP Markey, ...
Journal of proteome research 16 (5), 1924-1935, 2017
532017
Recombinant HA1 produced in E. coli forms functional oligomers and generates strain-specific SRID potency antibodies for pandemic influenza vaccines
S Khurana, C Larkin, S Verma, MB Joshi, J Fontana, AC Steven, LR King, ...
Vaccine 29 (34), 5657-5665, 2011
502011
Subdomain organization and catalytic residues of the F factor TraI relaxase domain
LM Street, MJ Harley, JC Stern, C Larkin, SL Williams, DL Miller, JA Dohm, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1646 (1-2), 86-99, 2003
492003
Capillary zone electrophoresis tandem mass spectrometry detects low concentration host cell impurities in monoclonal antibodies
G Zhu, L Sun, J Heidbrink‐Thompson, S Kuntumalla, H Lin, CJ Larkin, ...
Electrophoresis 37 (4), 616-622, 2016
352016
Rapid identification of biotherapeutics with label-free Raman spectroscopy
SK Paidi, S Siddhanta, R Strouse, JB McGivney, C Larkin, I Barman
Analytical chemistry 88 (8), 4361-4368, 2016
332016
Roles of active site residues and the HUH motif of the F plasmid TraI relaxase
C Larkin, RJF Haft, MJ Harley, B Traxler, JF Schildbach
Journal of Biological Chemistry 282 (46), 33707-33713, 2007
292007
Comprehensive analysis of host cell impurities in monoclonal antibodies with improved sensitivity by capillary zone electrophoresis mass spectrometry
Z Zhang, T Albanetti, T Linkous, CJ Larkin, R Schoner, JB McGivney IV, ...
Electrophoresis 38 (3-4), 401-407, 2017
232017
An intrastrand three-DNA-base interaction is a key specificity determinant of F transfer initiation and of F TraI relaxase DNA recognition and cleavage
K Hekman, K Guja, C Larkin, JF Schildbach
Nucleic acids research 36 (14), 4565-4572, 2008
232008
Storage conditions of conjugated reagents can impact results of immunogenicity assays
RJ Kubiak, N Lee, Y Zhu, WR Franch, SV Levitskaya, SR Krishnan, ...
Journal of Immunology Research 2016, 2016
172016
Crystallization and preliminary X-ray characterization of the relaxase domain of F factor TraI
C Larkin, S Datta, A Nezami, JA Dohm, JF Schildbach
Acta Crystallographica Section D: Biological Crystallography 59 (8), 1514-1516, 2003
142003
Quantitative analysis of the supernatant from host and transfected CHO cells using iTRAQ 8‐plex technique
G Zhu, L Sun, T Albanetti, T Linkous, C Larkin, R Schoner, ...
Biotechnology and Bioengineering 113 (10), 2140-2148, 2016
92016
Strategy for generating sequence-defined aptamer reagent sets for detecting protein contaminants in biotherapeutics
JB McGivney IV, AT Csordas, FM Walker, ER Bagley, EM Gruber, ...
Analytical chemistry 90 (5), 3262-3269, 2018
72018
A rapid lateral flow immunoassay for identity testing of biotherapeutics
LA Machiesky, O Côté, LH Kirkegaard, SC Mefferd, C Larkin
Journal of immunological methods 474, 112666, 2019
62019
Evaluation of continuous nonaffinity capture chromatography for a recombinant enzyme—optimization for a changing perfusion feedstream and comparison to batch processing
C Thompson, K Wilson, C Larkin, J Lee, WK Wang, M Wendeler
Biotechnology Progress 34 (5), 1195-1204, 2018
22018
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