| Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides BA Anderson, GC Freestone, A Low, CL De-Hoyos, WJD Iii, ... Nucleic Acids Research 49 (16), 9026-9041, 2021 | 68 | 2021 |
| Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins M Hyjek-Składanowska, TA Vickers, A Napiórkowska, BA Anderson, ... Journal of the American Chemical Society 142 (16), 7456-7468, 2020 | 63 | 2020 |
| Optimization of replication, transcription, and translation in a semi-synthetic organism AW Feldman, VT Dien, RJ Karadeema, EC Fischer, Y You, BA Anderson, ... Journal of the American Chemical Society 141 (27), 10644-10653, 2019 | 58 | 2019 |
| High-affinity DNA targeting using readily accessible mimics of N2′-functionalized 2′-Amino-α-L-LNA S Karmakar, BA Anderson, RL Rathje, S Andersen, TB Jensen, P Nielsen, ... The Journal of organic chemistry 76 (17), 7119-7131, 2011 | 38 | 2011 |
| Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA SP Sau, AS Madsen, P Podbevsek, NK Andersen, TS Kumar, S Andersen, ... The Journal of organic chemistry 78 (19), 9560-9570, 2013 | 37 | 2013 |
| C5‐Functionalized DNA, LNA, and α‐L‐LNA: Positional Control of Polarity‐Sensitive Fluorophores Leads to Improved SNP‐Typing ME Østergaard, P Kumar, B Baral, DC Guenther, BA Anderson, ... Chemistry–A European Journal 17 (11), 3157-3165, 2011 | 37 | 2011 |
| Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid) P Kumar, ME Østergaard, B Baral, BA Anderson, DC Guenther, M Kaura, ... The Journal of Organic Chemistry 79 (11), 5047-5061, 2014 | 33 | 2014 |
| Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes S Geny, PMD Moreno, T Krzywkowski, O Gissberg, NK Andersen, AJ Isse, ... Nucleic acids research 44 (5), 2007-2019, 2016 | 32 | 2016 |
| Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications DC Guenther, GH Anderson, S Karmakar, BA Anderson, BA Didion, ... Chemical science 6 (8), 5006-5015, 2015 | 27 | 2015 |
| Nanopore sequencing of an expanded genetic alphabet reveals high-fidelity replication of a predominantly hydrophobic unnatural base pair MP Ledbetter, JM Craig, RJ Karadeema, MT Noakes, HC Kim, SJ Abell, ... Journal of the American Chemical Society 142 (5), 2110-2114, 2020 | 23 | 2020 |
| C5-functionalized LNA: unparalleled hybridization properties and enzymatic stability ME Ostergaard, P Kumar, B Baral, DJ Raible, T Santhosh Kumar, ... ChemBioChem 10 (17), 2740, 2009 | 21 | 2009 |
| Recognition of Double-Stranded DNA Using Energetically Activated Duplexes Modified with N2′-Pyrene-, Perylene-, or Coronene-Functionalized 2′-N-Methyl-2 … BA Anderson, JJ Onley, PJ Hrdlicka The Journal of organic chemistry 80 (11), 5395-5406, 2015 | 16 | 2015 |
| Optimized DNA-targeting using triplex forming C5-alkynyl functionalized LNA SP Sau, P Kumar, BA Anderson, ME Østergaard, L Deobald, ... Chemical communications, 6756-6758, 2009 | 16 | 2009 |
| C5-amino acid functionalized LNA: positively poised for antisense applications DC Guenther, P Kumar, BA Anderson, PJ Hrdlicka Chemical communications 50 (64), 9007-9009, 2014 | 15 | 2014 |
| Synthesis and Characterization of Oligodeoxyribonucleotides Modified with 2′-Amino-α-l-LNA Adenine Monomers: High-Affinity Targeting of Single-Stranded DNA NK Andersen, BA Anderson, J Wengel, PJ Hrdlicka The Journal of organic chemistry 78 (24), 12690-12702, 2013 | 15 | 2013 |
| The Unexpected Base‐Pairing Behavior of Cyanuric Acid in RNA and Ribose versus Cyanuric Acid Induced Helicene Assembly of Nucleic Acids: Implications for the Pre‐RNA Paradigm BA Anderson, K Fauché, SC Karunakaran, JR Yerabolu, NV Hud, ... Chemistry–A European Journal 27 (12), 4033-4042, 2021 | 13 | 2021 |
| Heterogeneous Pyrophosphate‐Linked DNA–Oligonucleotides: Aversion to DNA but Affinity for RNA BA Anderson, R Krishnamurthy Chemistry–A European Journal 24 (26), 6837-6842, 2018 | 13 | 2018 |
| Merging two strategies for mixed-sequence recognition of double-stranded DNA: Pseudocomplementary Invader probes BA Anderson, PJ Hrdlicka The Journal of Organic Chemistry 81 (8), 3335-3346, 2016 | 12 | 2016 |
| Optimized synthesis of [3-15N]-labeled uridine phosphoramidites B Baral, P Kumar, BA Anderson, ME Østergaard, PK Sharma, PJ Hrdlicka Tetrahedron Letters 50 (42), 5850-5852, 2009 | 11 | 2009 |
| Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeutics BT Finicle, KH Eckenstein, AS Revenko, BA Anderson, WB Wan, ... Nucleic acids research 51 (4), 1583-1599, 2023 | 8 | 2023 |
