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Brooke A. Anderson
Brooke A. Anderson
Ionis Pharmaceuticals
Verified email at ionisph.com
Title
Cited by
Cited by
Year
Optimization of replication, transcription, and translation in a semi-synthetic organism
AW Feldman, VT Dien, RJ Karadeema, EC Fischer, Y You, BA Anderson, ...
Journal of the American Chemical Society 141 (27), 10644-10653, 2019
402019
Origins of the increased affinity of phosphorothioate-modified therapeutic nucleic acids for proteins
M Hyjek-Składanowska, TA Vickers, A Napiórkowska, BA Anderson, ...
Journal of the American Chemical Society 142 (16), 7456-7468, 2020
362020
C5‐Functionalized DNA, LNA, and α‐L‐LNA: Positional Control of Polarity‐Sensitive Fluorophores Leads to Improved SNP‐Typing
ME Østergaard, P Kumar, B Baral, DC Guenther, BA Anderson, ...
Chemistry–A European Journal 17 (11), 3157-3165, 2011
332011
Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA
SP Sau, AS Madsen, P Podbevsek, NK Andersen, TS Kumar, S Andersen, ...
The Journal of organic chemistry 78 (19), 9560-9570, 2013
312013
High-Affinity DNA Targeting Using Readily Accessible Mimics of N2′-Functionalized 2′-Amino-α-L-LNA
S Karmakar, BA Anderson, RL Rathje, S Andersen, TB Jensen, P Nielsen, ...
The Journal of organic chemistry 76 (17), 7119-7131, 2011
292011
Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid)
P Kumar, ME Østergaard, B Baral, BA Anderson, DC Guenther, M Kaura, ...
The Journal of organic chemistry 79 (11), 5047-5061, 2014
272014
Next-generation bis-locked nucleic acids with stacking linker and 2′-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes
S Geny, PMD Moreno, T Krzywkowski, O Gissberg, NK Andersen, AJ Isse, ...
Nucleic acids research 44 (5), 2007-2019, 2016
262016
Invader probes: Harnessing the energy of intercalation to facilitate recognition of chromosomal DNA for diagnostic applications
DC Guenther, GH Anderson, S Karmakar, BA Anderson, BA Didion, ...
Chemical science 6 (8), 5006-5015, 2015
222015
Towards next generation antisense oligonucleotides: mesylphosphoramidate modification improves therapeutic index and duration of effect of gapmer antisense oligonucleotides
BA Anderson, GC Freestone, A Low, CL De-Hoyos, WJD Iii, ...
Nucleic Acids Research 49 (16), 9026-9041, 2021
212021
C5‐Functionalized LNA: Unparalleled hybridization properties and enzymatic stability
ME Østergaard, P Kumar, B Baral, DJ Raible, T Santhosh Kumar, ...
ChemBioChem 10 (17), 2740-2743, 2009
192009
Optimized DNA-targeting using triplex forming C5-alkynyl functionalized LNA
SP Sau, P Kumar, BA Anderson, ME Østergaard, L Deobald, ...
Chemical communications, 6756-6758, 2009
162009
C5-amino acid functionalized LNA: positively poised for antisense applications
DC Guenther, P Kumar, BA Anderson, PJ Hrdlicka
Chemical Communications 50 (64), 9007-9009, 2014
132014
Synthesis and Characterization of Oligodeoxyribonucleotides Modified with 2′-Amino-α-l-LNA Adenine Monomers: High-Affinity Targeting of Single-Stranded DNA
NK Andersen, BA Anderson, J Wengel, PJ Hrdlicka
The Journal of organic chemistry 78 (24), 12690-12702, 2013
132013
Merging two strategies for mixed-sequence recognition of double-stranded DNA: Pseudocomplementary Invader probes
BA Anderson, PJ Hrdlicka
The Journal of organic chemistry 81 (8), 3335-3346, 2016
122016
Recognition of Double-Stranded DNA Using Energetically Activated Duplexes Modified with N2′-Pyrene-, Perylene-, or Coronene-Functionalized 2′-N-Methyl-2 …
BA Anderson, JJ Onley, PJ Hrdlicka
The Journal of Organic Chemistry 80 (11), 5395-5406, 2015
122015
Nanopore sequencing of an expanded genetic alphabet reveals high-fidelity replication of a predominantly hydrophobic unnatural base pair
MP Ledbetter, JM Craig, RJ Karadeema, MT Noakes, HC Kim, SJ Abell, ...
Journal of the American Chemical Society 142 (5), 2110-2114, 2020
102020
Heterogeneous Pyrophosphate‐Linked DNA–Oligonucleotides: Aversion to DNA but Affinity for RNA
BA Anderson, R Krishnamurthy
Chemistry–A European Journal 24 (26), 6837-6842, 2018
92018
Optimized synthesis of [3-15N]-labeled uridine phosphoramidites
B Baral, P Kumar, BA Anderson, ME Østergaard, PK Sharma, PJ Hrdlicka
Tetrahedron Letters 50 (42), 5850-5852, 2009
92009
The Unexpected Base‐Pairing Behavior of Cyanuric Acid in RNA and Ribose versus Cyanuric Acid Induced Helicene Assembly of Nucleic Acids: Implications for the Pre‐RNA Paradigm
BA Anderson, K Fauché, SC Karunakaran, JR Yerabolu, NV Hud, ...
Chemistry–A European Journal 27 (12), 4033-4042, 2021
72021
C5-alkynyl-functionalized α-L-LNA: Synthesis, thermal denaturation experiments and enzymatic stability
P Kumar, B Baral, BA Anderson, DC Guenther, ME Østergaard, ...
The Journal of organic chemistry 79 (11), 5062-5073, 2014
72014
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