| Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells RF Hoffmann, S Zarrintan, SM Brandenburg, A Kol, HG de Bruin, S Jafari, ... Respiratory research 14, 1-13, 2013 | 299 | 2013 |
| Cigarette smoke-induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis M van der Toorn, DJ Slebos, HG de Bruin, HG Leuvenink, SJL Bakker, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (5 …, 2007 | 188 | 2007 |
| Cigarette smoke irreversibly modifies glutathione in airway epithelial cells M van der Toorn, MP Smit-de Vries, DJ Slebos, HG de Bruin, N Abello, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 293 (5 …, 2007 | 163 | 2007 |
| Cigarette smoke–induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release IH Heijink, SD Pouwels, C Leijendekker, HG de Bruin, GJ Zijlstra, ... American journal of respiratory cell and molecular biology 52 (5), 554-562, 2015 | 105 | 2015 |
| Role of aberrant WNT signalling in the airway epithelial response to cigarette smoke in chronic obstructive pulmonary disease IH Heijink, HG de Bruin, M van den Berge, LJC Bennink, SM Brandenburg, ... Thorax 68 (8), 709-716, 2013 | 105 | 2013 |
| Caveolin-1 controls airway epithelial barrier function. Implications for asthma TL Hackett, HG de Bruin, F Shaheen, M van den Berge, ... American journal of respiratory cell and molecular biology 49 (4), 662-671, 2013 | 101 | 2013 |
| Cigarette smoke-induced epithelial expression of WNT-5B: implications for COPD IH Heijink, HG de Bruin, R Dennebos, MR Jonker, JA Noordhoek, ... European Respiratory Journal 48 (2), 504-515, 2016 | 72 | 2016 |
| A-kinase anchoring proteins contribute to loss of E-cadherin and bronchial epithelial barrier by cigarette smoke A Oldenburger, WJ Poppinga, F Kos, HG de Bruin, WF Rijks, IH Heijink, ... American Journal of Physiology-Cell Physiology 306 (6), C585-C597, 2014 | 71 | 2014 |
| Critical role of aldehydes in cigarette smoke-induced acute airway inflammation M van der Toorn, DJ Slebos, HG de Bruin, R Gras, D Rezayat, L Jorge, ... Respiratory research 14, 1-12, 2013 | 62 | 2013 |
| Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice S Post, IH Heijink, AH Petersen, HG de Bruin, AJM van Oosterhout, ... PloS one 9 (3), e91206, 2014 | 51 | 2014 |
| Mitochondrial dysfunction increases pro-inflammatory cytokine production and impairs repair and corticosteroid responsiveness in lung epithelium RF Hoffmann, MR Jonker, SM Brandenburg, HG De Bruin, ... Scientific reports 9 (1), 15047, 2019 | 48 | 2019 |
| Pellino-1 selectively regulates epithelial cell responses to rhinovirus JA Bennett, LR Prince, LC Parker, CA Stokes, HG de Bruin, ... Journal of virology 86 (12), 6595-6604, 2012 | 42 | 2012 |
| Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression IM Boudewijn, A Faiz, K Steiling, E van der Wiel, ED Telenga, ... Respiratory research 18, 1-10, 2017 | 40 | 2017 |
| Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD A Ngkelo, RF Hoffmann, AL Durham, JA Marwick, SM Brandenburg, ... American journal of physiology-lung cellular and molecular physiology 309 …, 2015 | 33 | 2015 |
| Cigarette smoke induced DAMP release from necrotic neutrophils triggers pro-inflammatory mediator release IH Heijink, SD Pouwels, C Leijendekker, HG de Bruin, GJ Zijlstra, ... Am J Respir Cell Mol Biol 52 (5), 554-562, 2015 | 21 | 2015 |
| Abnormalities in reparative function of lung-derived mesenchymal stromal cells in emphysema DMLW Kruk, M Wisman, HG Bruin, ME Lodewijk, DJ Hof, T Borghuis, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 320 (5 …, 2021 | 18 | 2021 |
| Paracrine regulation of alveolar epithelial damage and repair responses by human lung-resident mesenchymal stromal cells DMLW Kruk, M Wisman, JA Noordhoek, M Nizamoglu, MR Jonker, ... Cells 10 (11), 2860, 2021 | 16 | 2021 |
| Viral mimic poly-(I: C) attenuates airway epithelial T-cell suppressive capacity: implications for asthma J Schwarze, PM Fitch, J Heimweg, C Errington, R Matsuda, HG de Bruin, ... European Respiratory Journal 48 (6), 1785-1788, 2016 | 11 | 2016 |
| Inhibition of β‐catenin/CBP signalling improves airway epithelial barrier function and suppresses CCL20 release VNS Kuchibhotla, MR Jonker, HG de Bruin, JA Noordhoek, DA Knight, ... Allergy 75 (7), 1786, 2020 | 7 | 2020 |
| A role for WNT-5B in airway remodeling in COPD by activation of TGF-β/Smad3 signaling? I Heijink, H de Bruin, R Dennebos, M van den Berge, R Gosens, ... European Respiratory Journal 42 (Suppl 57), 2013 | 3 | 2013 |
Nick ten HackenAssociate Professor, University Medical Center Groningen (UMCG), University Groningen (RUG)Verified email at umcg.nl
