Ghassan Abu Sheikha
Ghassan Abu Sheikha
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Synthesis, structure, and antiproliferative activity of selenophenfurin, an inosine 5 ‘-monophosphate dehydrogenase inhibitor analogue of selenazofurin
P Franchetti, L Cappellacci, GA Sheikha, HN Jayaram, VV Gurudutt, T Sint, ...
Journal of medicinal chemistry 40 (11), 1731-1737, 1997
Elaborate ligand-based pharmacophore exploration and QSAR analysis guide the synthesis of novel pyridinium-based potent β-secretase inhibitory leads
A Al-Nadaf, GA Sheikha, MO Taha
Bioorganic & medicinal chemistry 18 (9), 3088-3115, 2010
Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration
RA Khalaf, GA Sheikha, Y Bustanji, MO Taha
European journal of medicinal chemistry 45 (4), 1598-1617, 2010
Pharmacophore and QSAR modeling of estrogen receptor β ligands and subsequent validation and in silico search for new hits
MO Taha, M Tarairah, H Zalloum, G Abu-Sheikha
Journal of Molecular Graphics and Modelling 28 (5), 383-400, 2010
Synthesis and evaluation of the anti-HIV activity of aza and deaza analogs of isoddA and their phosphates as prodrugs
P Franchetti, L Cappellacci, M Grifantini, L Messini, GA Sheikha, AG Loi, ...
Journal of medicinal chemistry 37 (21), 3534-3541, 1994
Preparation of mucoadhesive oral patches containing tetracycline hydrochloride and carvacrol for treatment of local mouth bacterial infections and candidiasis
RM Obaidat, A Bader, W Al-Rajab, G ABU SHEIKHA, AA Obaidat
Scientia pharmaceutica 79 (1), 197-212, 2011
Synthesis and antiviral activity of 8-aza analogs of chiral [2-(phosphonomethoxy) propyl] guanines
P Franchetti, G Abu Sheikha, L Cappellacci, M Grifantini, A De Montis, ...
Journal of medicinal chemistry 38 (20), 4007-4013, 1995
A new acyclic heterodinucleotide active against human immunodeficiency virus and herpes simplex virus
P Franchetti, GA Sheikha, L Cappellacci, S Marchetti, M Grifantini, ...
Antiviral research 47 (3), 149-158, 2000
8-Aza-analogues of PMEA and PMEG: Synthesis and in vitro anti-HIV activity
P Franchetti, GA Sheikha, L Cappellacci, L Messini, M Grifantini, AG Loi, ...
Nucleosides, Nucleotides & Nucleic Acids 13 (8), 1707-1719, 1994
Computer-aided design, synthesis, and biological evaluation of new indole-2-carboxamide derivatives as PI3Kα/EGFR inhibitors
K Sweidan, DA Sabbah, S Bardaweel, KA Dush, GA Sheikha, ...
Bioorganic & medicinal chemistry letters 26 (11), 2685-2690, 2016
Synthesis and Anti-Hyperlipidemic Evaluation of N‑(Benzoylphenyl)-5-fluoro-1H-indole-2-carboxamide Derivatives in Triton WR-1339-Induced Hyperlipidemic Rats
G Shattat, R Al-Qirim, Y Al-Hiari, GA Sheikha, T Al-Qirim, W El-Huneidi, ...
Molecules 15 (9), 5840-5849, 2010
A new class of acyclic nucleoside phosphonates: synthesis and biological activity of 9-{[(phosphonomethyl) aziridin-1-yl] methyl} guanine (pmamg) and analogues
GA Sheikha, P La Colla, AG Loi
Nucleosides, Nucleotides and Nucleic Acids 21 (10), 619-635, 2002
In Vivo Antihyperlipidemic Activity of a New Series of N‐(Benzoylphenyl) and N‐(Acetylphenyl)‐1‐benzofuran‐2‐carboxamides in Rats
T Al‐Qirim, G Shattat, K Sweidan, W El‐Huneidi, GA Sheikha, RA Khalaf, ...
Archiv der Pharmazie 345 (5), 401-406, 2012
Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα)
DA Sabbah, M Saada, RA Khalaf, S Bardaweel, K Sweidan, T Al-Qirim, ...
Bioorganic & medicinal chemistry letters 25 (16), 3120-3124, 2015
Antihyperlipidemic properties of novel N-(benzoylphenyl)-5-substituted-1H-indole-2-carboxamides in Triton WR-1339-induced hyperlipidemic rats
Y Al-Hiari, G Shattat, T Al-Qirim, W El-Huneidi, GA Sheikha, S Hikmat
Molecules 16 (10), 8292-8304, 2011
Synthesis and preliminary biological evaluation of new heterocyclic carboxamide models
K Sweidan, J Engelmann, W Abu Rayyan, D Sabbah, M Abu Zarga, ...
Letters in Drug Design & Discovery 12 (5), 417-429, 2015
Homology modeling of MCH1 receptor and validation by docking/scoring and protein-aligned CoMFA
A Abu-Hammad, WA Zalloum, H Zalloum, G Abu-Sheikha, MO Taha
European journal of medicinal chemistry 44 (6), 2583-2596, 2009
The Pharmacological effects of novel 5-fluoro-N-(9, 10-dihydro-9, 10-dioxoanthracen-8-yl)-1 H-indole-2-carboxamide derivatives on plasma lipid profile of Triton-WR-1339-inducedá…
G Shattat, T Al-Qirim, GA Sheikha, Y Al-Hiari, K Sweidan, R Al-Qirim, ...
Journal of enzyme inhibition and medicinal chemistry 28 (4), 863-869, 2013
Acyclic nucleotides related to clitocine: Synthesis and anti-HIV activity
P Franchetti, L Cappellacci, GA Sheikha, M Grifantini, AG Loi, AD Montis, ...
Nucleosides, Nucleotides & Nucleic Acids 14 (3-5), 607-610, 1995
Synthesis and pharmacological evaluation of novel unsubstituted indole-anthraquinone carboxamide derivatives as potent antihyperlipidemic agents
M Al-Najdawi, Y Hiari, T Qirim, G Shattat, M Al-Zweri, GA Sheikha
Zeitschrift FŘr Naturforschung C 69 (1-2), 21-28, 2014
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