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Chander Singh Digwal
Chander Singh Digwal
Verified email at mskcc.org
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Year
VOSO4 catalyzed highly efficient synthesis of benzimidazoles, benzothiazoles, and quinoxalines
CS Digwal, U Yadav, AP Sakla, PVS Ramya, S Aaghaz, A Kamal
Tetrahedron Letters 57 (36), 4012-4016, 2016
702016
Synthesis and biological evaluation of curcumin inspired indole analogues as tubulin polymerization inhibitors
PVS Ramya, S Angapelly, L Guntuku, CS Digwal, BN Babu, VGM Naidu, ...
European Journal of Medicinal Chemistry 127, 100-114, 2017
692017
Curcumin inspired 2-chloro/phenoxy quinoline analogues: Synthesis and biological evaluation as potential anticancer agents
AK P. V. Sri Ramya, Lalita Guntuku, Srinivas Angapelly, Shailaja Karri ...
Bioorganic & Medicinal Chemistry Letters, 2018
482018
Synthesis and biological evaluation of curcumin inspired imidazo [1, 2-a] pyridine analogues as tubulin polymerization inhibitors
PVS Ramya, L Guntuku, S Angapelly, CS Digwal, UJ Lakshmi, ...
European journal of medicinal chemistry 143, 216-231, 2018
482018
PET molecular imaging in drug development: the imaging and chemistry perspective
SG Nerella, P Singh, T Sanam, CS Digwal
Frontiers in Medicine 9, 812270, 2022
462022
A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond
T Taldone, T Wang, A Rodina, NVK Pillarsetty, CS Digwal, S Sharma, ...
Cold Spring Harbor perspectives in biology, a034116, 2019
362019
Discovery of curcumin inspired sulfonamide derivatives as a new class of carbonic anhydrase isoforms I, II, IX, and XII inhibitors
PVS Ramya, S Angapelly, A Angeli, CS Digwal, M Arifuddin, BN Babu, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 32 (1), 1274-1281, 2017
322017
Vanadium-Catalyzed Oxidative C (CO)–C (CO) Bond Cleavage for C–N Bond Formation: One-Pot Domino Transformation of 1, 2-Diketones and Amidines into Imides and Amides
CS Digwal, U Yadav, PVS Ramya, S Sana, B Swain, A Kamal
The Journal of Organic Chemistry 82 (14), 7332-7345, 2017
292017
Structural and functional complexity of HSP90 in cellular homeostasis and disease
G Chiosis, CS Digwal, JB Trepel, L Neckers
Nature Reviews Molecular Cell Biology 24 (11), 797-815, 2023
272023
Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system
A Bolaender, D Zatorska, H He, S Joshi, S Sharma, CS Digwal, HJ Patel, ...
Nature Communications 12 (1), 4669, 2021
202021
Hypervalent iodine (III) catalyzed rapid and efficient access to benzimidazoles, benzothiazoles and quinoxalines: Biological evaluation of some new benzimidazole-imidazo [1, 2 …
PVS Ramya, S Angapelly, RS Rani, CS Digwal, CG Kumar, BN Babu, ...
Arabian Journal of Chemistry 13 (1), 120-133, 2020
182020
Imidazo[1,2-a]pyridines linked with thiazoles/thiophene motif through keto spacer as potential cytotoxic agents and NF-κB inhibitors
MA Kamala K. Vasu, Chander Singh Digwal, Amit N. Pandya, Dhaivat H. Pandya ...
Bioorganic & Medicinal Chemistry Letters, 2017
182017
Disease‐specific interactome alterations via epichaperomics: the case for Alzheimer’s disease
SD Ginsberg, TA Neubert, S Sharma, CS Digwal, P Yan, C Timbus, ...
The FEBS journal 289 (8), 2047-2066, 2022
172022
Synthesis and exploration of 2-morpholino-4-phenylthiazol-5-yl acrylamide derivatives for their effects against carbonic anhydrase I, II, IX and XII isoforms as a non …
B Swain, CS Digwal, A Angeli, M Alvala, P Singh, CT Supuran, ...
Bioorganic & Medicinal Chemistry 27 (21), 115090, 2019
142019
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
S Joshi, EDG Gomes, T Wang, A Corben, T Taldone, S Gandu, C Xu, ...
Communications Biology 4 (1), 1333, 2021
122021
Design and synthesis of 5‐Morpholino‐Thiophene‐Indole/Oxindole hybrids as cytotoxic agents
U Yadav, AP Sakla, R Tokala, ST Nyalam, A Khurana, CS Digwal, V Talla, ...
ChemistrySelect 5 (14), 4356-4363, 2020
112020
Chemical probes and methods for single-cell detection and quantification of epichaperomes in hematologic malignancies
S Merugu, S Sharma, J Kaner, C Digwal, M Sugita, S Joshi, T Taldone, ...
Methods in enzymology 639, 289-311, 2020
92020
How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view
M Castelli, P Yan, A Rodina, CS Digwal, P Panchal, G Chiosis, E Moroni, ...
Structure 31 (8), 987-1004. e8, 2023
82023
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
A Rodina, C Xu, CS Digwal, S Joshi, Y Patel, AR Santhaseela, S Bay, ...
Nature communications 14 (1), 3742, 2023
82023
An efficient RuCl3· H2O/I2 catalytic system: A facile access to 3-aroylimidazo [1, 2-a] pyridines from 2-aminopyridines and chalcones
PVS Ramya, S Angapelly, CS Digwal, U Yadav, BN Babu, A Kamal
Journal of Saudi Chemical Society 22 (1), 90-100, 2018
72018
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